A prospective comparison of transvaginal, transabdominal ultrasound and diagnostic curettage in the evaluation of endometrial pathology

Sedeq, Media Ghazi; Muhammad, Parez Radham; Mohammed, Samira S. Shekh; Alalaf, Shahla K.

doi:10.15218/zjms.2016.0010

Cited by 4 publications

(4 citation statements)

References 9 publications

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“…22 Another study done in our locality in Erbil showed sensitivity and specificity of vaginal ultrasound in the detection of endometrial pathologies were 100% and 94.7%. 25 Another study done by Showkat et al showed a sensitivity of transvaginal ultrasound in the detection of endometrial carcinoma of 67%, specificity 100%, accuracy 98%, positive predictive value 100% and negative predictive value 97%. 26 Transvaginal sonographic scanning is gold slandered investigation for postmenopausal women with vaginal bleeding.…”

Section: Discussionmentioning

confidence: 97%

Can vaginal ultrasound replace diagnostic curettage in the detection of endometrial pathology in post-menopausal bleeding?

et al. 2019

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Introduction Postmenopausal bleeding refers to vaginal bleeding that occurs after twelve months of amenorrhea in a woman of the age where the menopause can be expected. 1 It can also be defined as the time in a woman's life when the woman stops having a menstrual period permanently and is no longer fertile. 2 However, it can be applied to younger women following premature ovarian failure or premature menopause. 3 Vaginal bleeding is a common post menopausal complaint representing 5% of all gynecology outpatient consultations. 4 The incidence of postmenopausal bleeding is 10% in the general population immediately after menopause. 5 The causes of postmenopausal bleeding include endometrial atrophy (approximately 75% of cases), 3 endometrial polyps, submucosal fibroids, endometrial hyperplasia (simple, complex and atypical), endometrial carcinoma (approximately 10%), and estrogen withdrawal. 6 Non-gynecological causes include trauma, systemic diseases like hypertension, hypothyroidism, and bleeding disorders. 3 Endometrial abnormalities are common diagnostic challenges facing the radiologist and referring specialist gynecologist. Ultrasound is the primary imaging modality in this workup; findings if further investigations done like sonohysterography, hysterosalpingography, magnetic resonance imaging, and computed tomography are often correlated Background and objective: Post-menopausal bleeding due to endometrial abnormalities is a common diagnostic challenge facing the ultrasonogists and referring gynecologists. This study aimed to detect the validity of transvaginal ultrasound to detect endometrial pathologies and its sensitivity and specificity for determining endometrial carcinoma in women with postmenopausal bleeding. Methods: A diagnostic accuracy study of transvaginal ultrasound and diagnostic curettage was conducted for evaluation of endometrial pathology in the College of Medicine, Hawler Medical University from October2016to January 2018. The sample size included 55 women with post-menopausal vaginal bleeding. The ultrasound findings were compared with histopathological results of endometrial biopsy. Results: Out of 55 women, 49.09% had endometrial atrophy, 29.09% had endometrial hyperplasia, 16.36% had endometrial polyp, 3.64% had endometrial carcinoma, and 1.82% had hyperplasia with atypia according to histopathological findings. The sensitivity of ultrasound in detecting cancer was 66.7%, the specificity was 100%, the positive predictive value (PV) was 100%, and the negative predictive value was 98.1%. The total agreement rate was 98.2%. Conclusion: Transvaginal ultrasound is an excellent diagnostic tool to determine whether further investigation with histopathological examination of endometrial biopsy is necessary for postmenopausal vaginal bleeding.

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Section: Discussionmentioning

confidence: 97%

Can vaginal ultrasound replace diagnostic curettage in the detection of endometrial pathology in post-menopausal bleeding?

et al. 2019

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“…In postmenopausal women, because the endometrium undergoes a long period of exposure to risk factors, the etiology of PMB may be due to benign, such as atrophy, endometritis or EH, but these women show a higher percentage of malignancy than perimenopausal women. 19 , 20 , 21 , 22 , 23 Because our study did not involve clinical intervention, only patients with histopathological results were recruited, and these results were compared with the ultrasound results. Participants lacking histopathological results were excluded from the study; therefore, endometrial atrophy and normal endometrium were rare in the present study.…”

Section: Discussionmentioning

confidence: 99%

Assessment of paraclinical characteristics in peri- and postmenopausal bleeding women: is there a correlation between hemoglobin levels and ultrasonic indices?

Nguyen

2023

Journal of Taibah University Medical Sciences

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“…Despite existing difference in study population, generally, menorrhagia is still the common type of bleeding in perimenopausal women with AUB. [ 34 35 36 ] Dilation and curettage by Karman cannula is considered as an adequate method for the hemorrhagic treatment and endometrial sampling biopsy, thus, almost cases underwent this interventional procedure in our study [ Figure 3 ]. [ 37 ] According to Gupta et al ., the use of Karman cannula resulted in less pain and is a much cheaper option in comparison to Pipelle.…”

Section: Discussionmentioning

confidence: 99%

Evaluating Clinical Features in Intracavitary Uterine Pathologies among Vietnamese Women Presenting with Peri-and Postmenopausal Bleeding

Nguyen

Nguyen²

2022

Journal of Mid-Life Health

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Background: Intracavitary uterine pathologies (IUPs) may be resulting in vaginal bleeding in perimenopausal and postmenopausal women. Especially, malignant disease needed to be investigated due to its adverse impact on the quality of mid-life women as well as the burden of health-care costs in low- and middle-income countries such as Vietnam. Objective: Thereby, through this study, we aimed to assess the major clinical features of IUPs in women with perimenopausal and postmenopausal bleeding women. Materials and Methods: This was a cross-sectional observational study at Hue University Hospital and Hue Central Hospital from June 2016 to June 2019. The study enrolled 150 women above 40 years old involving with intrauterine bleeding. Results: The mean age of the study population was 51.51 ± 7.65. The most common symptom in perimenopausal women was menorrhagia, up to 62.2% of cases. In addition to intrauterine bleeding, there were 54.7% of cases had at least one other functional symptom, they were pale skin (35.9%), and lower abdominal pain (31.3). Endometrial hyperplasia (EH) was the most common pathology in both groups with perimenopausal and postmenopausal bleeding (PMB), respectively, 66.7% and 51.7%. In PMB group, endometrial cancer (EC) occupied approximately 38.3% following EH. Our study revealed age, menstrual characteristics, and diabetes in relation to malignant disease. Other factors seemed to be less associated with EC. Conclusions: Menorrhagia was the most common type of abnormal uterine bleeding in perimenopausal women. Besides vaginal bleeding, others symptoms such as pale skin, pelvic pain, and fatigue were also common. Length day and blood loss before hospitalization in perimenopausal women were greater significantly than that in postmenopausal women. Age, menstrual characteristics, and diabetes increased the risk of EC in women with PMB.

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A prospective comparison of transvaginal, transabdominal ultrasound and diagnostic curettage in the evaluation of endometrial pathology

Cited by 4 publications

References 9 publications

Can vaginal ultrasound replace diagnostic curettage in the detection of endometrial pathology in post-menopausal bleeding?

Can vaginal ultrasound replace diagnostic curettage in the detection of endometrial pathology in post-menopausal bleeding?

Assessment of paraclinical characteristics in peri- and postmenopausal bleeding women: is there a correlation between hemoglobin levels and ultrasonic indices?

Evaluating Clinical Features in Intracavitary Uterine Pathologies among Vietnamese Women Presenting with Peri-and Postmenopausal Bleeding

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