A prospective evaluation of glucose reagent teststrips in the prehospital setting

Lavery, Robert F.; Cody, Ronald P.; Zacharias, Daniel; Schreck, David M.

doi:10.1016/0735-6757(91)90046-m

Cited by 18 publications

(4 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is nevertheless possible to find studies that focus on the consistency of glucose values in venous (plasma) and capillary (whole-blood) samples in emergent conditions 8–10. Ullal et al reported that the measurements made by various glucometers in and outside the hospital were well correlated with laboratory results 11.…”

Section: Discussionmentioning

confidence: 99%

Low perfusion index affects the difference in glucose level between capillary and venous blood

Acar

Özçelik

Çevik

et al. 2014

TCRM

View full text Add to dashboard Cite

AimIn emergency cases, finger stick testing is primarily used to check the blood glucose value of patients since it takes longer to obtain the venous value. In critical patients, under conditions that cause an increase in metabolic state and level of stress, there occurs considerable difference in glucose levels between capillary and venous measurements. This study aimed to investigate the comparability of capillary and venous glucose values, according to the perfusion index level obtained with the Masimo Radical-7® device, in critical patients aged 18 years and over.MethodWe conducted this prospective and observational study in the emergency department of the Eskisehir Osmangazi University hospital between November 3, 2008 and February 2, 2009.ResultsThe blood glucose of 300 critical patients was checked by finger stick in the emergency unit. The participants with normal vital signs had perfusion index between 0 and 5; the results obtained by the two methods were more consistent for perfusion index values of 6 and over. The results were most consistent in aged participants with normal vital sign findings and low perfusion index and in young patients with high perfusion index. In the cases where at least one of the vital signs was abnormal, the glucose values obtained by the two methods were more consistent when the perfusion index was 6 or over. In this group, independently from the perfusion index value, the consistency was higher in younger patients compared with aged patients.ConclusionIn the emergency department, perfusion index value measured by Masimo Radical-7 and capillary blood glucose levels can serve in blood sugar management in critically ill patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Low perfusion index affects the difference in glucose level between capillary and venous blood

Acar

Özçelik

Çevik

et al. 2014

TCRM

View full text Add to dashboard Cite

show abstract

“…12,13 Although FSBG testing is known to be safe and accurate in the prehospital setting, obtaining this measurement in actively seizing patients is difficult, likely increases the time required to perform the procedure, and may increase the risk of prehospital personnel exposure to blood-borne pathogens. 14,15 Another potential consequence of getting an early FSBG in actively seizing patients is that it may delay the administration of a benzodiazepine in patients whose seizing is unrelated to blood glucose levels.…”

Section: Introductionmentioning

confidence: 99%

When Should You Test for and Treat Hypoglycemia in Prehospital Seizure Patients?

Beskind

Rhodes

Stolz³

et al. 2014

Prehospital Emergency Care

View full text Add to dashboard Cite

Rates of hypoglycemia were very low in patients treated by EMS for seizure. Glucose testing prior to benzodiazepine administration significantly increased the median time to benzodiazepine administration. Given the importance of rapid treatment of seizure in actively seizing patients, measurement of blood glucose prior to treating a seizure with a benzodiazepine is not supported by our study. EMS seizure protocols should be revisited.

show abstract

“…When using the reagent strips, a cutoff of less than 60 mg/dL fails to detect hypoglycemia in 6-8% of cases. 18,19 To compensate for this, it is recommended that the cutoff should be raised to 120 mg/ dL for administration of dextrose in patients with an altered mental status and a nonfocal neurologic exam. 2 The accuracy of the glucometer has not been validated in the out-of-hospital or ED setting.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Hyperglycemia on Cocaine Neurotoxicity and Death in Mice

Bania¹,

Perez²,

Carey³

et al. 2000

Academic Emergency Medicine

View full text Add to dashboard Cite

Abstract. Objective: Cocaine toxicity frequently manifests as seizures and status epilepticus. Frequently, dextrose is administered to patients with cocaine-induced seizures. The objective of this study was to examine the effect of pre-existing hyperglycemia on cocaine neurotoxicity and death in mice. Methods: Swiss albino mice received intraperitoneal dextrose at a dose of 1 g/kg (12.5%) (hyperglycemic group, n = 98). The euglycemic group (n = 98) received an equal volume of 0.9% saline. After 60 minutes, all the animals received intraperitoneal cocaine at a dose of 90 mg/kg. The times to onset of ataxia, seizure, and death were recorded in seconds. Times to events were compared using a Kaplan-Meier method and results were compared using the logrank test. The overall percentage outcomes were compared using chi-square. Results: The ataxia rates (hyperglycemic 97%, euglycemic 97%, 2 = 0, p = 1), seizure rates (hyperglycemic 85%, euglycemic 82%, 2 = 0.292, p = 0.589), and survival rates (hyperglycemic 62%, euglycemic 51%, 2 = 0.2514, p = 0.113) were similar between the groups. The survival following a seizure was significantly higher in the hyperglycemic group (hyperglycemic 57%, euglycemic 41%, 2 = 4.439, p = 0.035). The median ataxia time was earlier in the hyperglycemic group (190 sec) than in the euglycemic group (166 sec) (p = 0.031). Seizures occurred no earlier in the hyperglycemic group (331 sec) than in the euglycemic group (342 sec) (p = 0.207). Survival times were not different for the hyperglycemic group (9,133 sec) and the euglycemic group (7,593 sec) (p = 0.394). Survival times following seizures were not different for the hyperglycemic group (8,095 sec) and the euglycemic group (5,816 sec) (p = 0.0752). Conclusions: In mice with pre-existing hyperglycemia, ataxia occurred earlier and survival following cocaine-induced seizures was longer than for euglycemic mice. No significant difference in the overall percentage of seizures and death was detected. Pre-existing hyperglycemia had minimal effect on worsening cocaine toxicity in mice. Key words: cocaine; neurotoxicity; hyperglycemia. ACADEMIC EMERGENCY MEDICINE 2000; 7:974-979 C OCAINE is a frequent cause of seizures and status epilepticus treated by emergency physicians and out-of-hospital care providers. The initial management of all seizures includes stabilization of the airway and cervical spine, ensuring adequate oxygenation, and evaluation and treatment of hypoglycemia. Glucose determination is important because hypoglycemia is a common cause of seizures and status epilepticus, and can easily be corrected by the administration of dextrose. 1Many out-of-hospital care protocols administer dextrose without an evaluation of the glucose level. In addition, some physicians recommend the administration of dextrose if the bedside determination is less than 120 mg/dL because these tests may not detect hypoglycemia if a lower level is used. 2Hyperglycemia worsens neurologic outcome and increases mortality in experimental models of cerebral ischemia.3-5 Co...

show abstract

A prospective evaluation of glucose reagent teststrips in the prehospital setting

Cited by 18 publications

References 36 publications

Low perfusion index affects the difference in glucose level between capillary and venous blood

Low perfusion index affects the difference in glucose level between capillary and venous blood

When Should You Test for and Treat Hypoglycemia in Prehospital Seizure Patients?

The Effect of Hyperglycemia on Cocaine Neurotoxicity and Death in Mice

Contact Info

Product

Resources

About