A prospective randomized double-blinded controlled study of ropivacaine 0.75% versus bupivacaine 0.5%-mepivacaine 2% for peribulbar anesthesia

A Comparison of Mepivacaine Versus Lidocaine for Episcleral (Sub-Tenon’s) Block for Cataract Surgery in an Ambulatory Setting

“…Lidocaine and mepivacaine are both amide local anesthetics with short onset, intermediate duration, and similar potency. [2][3][4][5] Regardless of the block used, mepivacaine is classically reported to have similar onset time but slightly longer effect than that of lidocaine. [2][3][4][5][6][7][8]12 In a work on epidural anesthesia, mepivacaine had a similar duration to a lidocaine-epinephrine mixture, which is expected to provide longer block duration than does plain lidocaine.…”

“…Mepivacaine is now widely used for eye blocks. 2,3 Lidocaine is classically assumed to provide slightly shorter duration than does mepivacaine, in a multitude of blocks (epidural, peripheral, and even eyelid blocks). [4][5][6][7][8] This point has not been explored by use of episcleral (sub-Tenon's) block for eye surgery.…”

Mepivacaine Alters Vascular Responsiveness to Vasoconstrictors in Aortic Rings from Normal and Aortic‐Banded Rats

“…Local anaesthetics‐induced cardiovascular toxicity is most commonly seen when performing epidural blocks, brachial plexus blocks or major lower limb blocks (Stoelting 1999a). However, there are also few reports for cardiovascular adverse effects following local anaesthesia in dentistry, in ophthalmic and in oral and maxillofacial surgery (Daublander et al 1997; Luchetti et al 2000; Enlund et al 2001).…”