A prospective randomized study of heparin-bonded graft (Propaten) versus standard graft in prosthetic arteriovenous access

Abstract

Heparin-bonded grafts demonstrated a trend to improved patency, but the difference was not statistically significant. Heparin-bonded grafts had a significantly lower early thrombosis rate that was sustained only for the first 5 months of follow-up.

Hemocompatibility of hyaluronan enhanced linear low density polyethylene for blood contacting applications

“…Some examples to enhance hemocompatibility include plasma surface modification, the grafting of oligo and poly(ethylene glycol)s (OEG, PEG), zwitterionic structures, heparin modification, the fabrication of PEGylated terapolymers, and the endothelialization of biomaterial surfaces. 1,3,[7][8][9][10][11][12][13][14][15][16][17][18][19] . Among the many techniques proposed to enhance hemocompatibility, much success has been found through the exploration of hyaluronan (HA) enhanced surfaces which have been shown to placate the hemostatic response.…”

Comparison of standard forearm prosthetic loop grafts to composite semiloop forearm grafts (“semi‐grafts”) in hemodialysis patients: A prospective study

“…First, it is a nonrandomized study and represents the description of a single center/surgeon experience which limits its external generalizability to surgeons less experienced in AVG primary operations and revisions. This may have had a positive impact on our results in contrast to multicenter studies producing overall lower patency rates . Second, the sample size of the SG‐group was rather small for important clinical implications for the unbiased presentation of this new vascular access option.…”

“…This may have had a positive impact on our results in contrast to multicenter studies producing overall lower patency rates. 35 Second, the sample size of the SG-group was rather small for important clinical implications for the unbiased presentation of this new vascular access option. It may be possible that larger SG cohort could bring this close to significance superior patency of SGs to statistically significant level.…”

Equivalent outcomes with standard and heparin-bonded expanded polytetrafluoroethylene grafts used as conduits for hemodialysis access

“…They did note that the HB-PTFE grafts had significantly less thrombosis in first 5 months after implantation than the S-PTFE graft. 15 The cost of HB-PTFE grafts has been reported to be 18% more than that of S-PTFE grafts. 6 One study estimated that the difference was $650 for equivalent graft lengths, and in their hands, if no heparin grafts were used over period of their study, the total institutional cost savings would translate to $39,404 in 2013 dollars (w$938 per month).…”