A prospective study of 1152 hospital autopsies: I. Inaccuracies in death certification

Cameron, Helen; McGoogan, E

doi:10.1002/path.1711330402

Cited by 271 publications

(90 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Death cert ificate diagnosis has been demonstrated to decrea se in accuracy with age at death (2). Given the fact that mesothelioma generally appears late in life (47 070 of the mesotheliomas in this series caused death at the age of 65 years or over), the disease may have been particularly prone to underreporting in the earlier years of the Register.…”

Section: Discussionmentioning

confidence: 83%

Mesothelioma in Great Britain in 1968-1983.

Jones¹,

Smith²,

Thomas³

1988

Scand J Work Environ Health

View full text Add to dashboard Cite

JONES RD, SMITH DM, THOMAS PG. Mesothelioma in Great Britain in 1968-1983. Scand J Work En viron Health 14 (1988 145-152. The British mesothelioma register records deaths in Great Britain when the word " mesothelioma" is on the death certificate. In 1968-1983 the mesotheliomadeaths among men increased from 114 to 467, while those among women increased from 38 to 90. In 1983 the crude mesothelioma death rates were 17.5 per millionand 3.2 per million for the men and women, respectively . The Northern region had the highest crude rates. At the county level, the highest crude deaths rates in 1976-1983 were recorded for the men in Devon and for the women in Lancashire. Marked differences occurred in the ratio of deaths among men to deaths among women for mesothelioma of the pleura (4.6 : I) and for mesothelioma of the peritoneum (2: I). The age-specific death rates for men and women diverged markedly for pleural mesothelioma but not for peritoneal mesothelioma. Trends in the use of asbestos and in age-and sex-specific death rates suggest that the annual number of mesothelioma deaths will continue to increase, possibly until the turn of the century. This increase will be concentrated among the men as the main asbestos exposure of women occurred during the war and the annual deaths due to this exposure may have already peaked.

show abstract

Section: Discussionmentioning

confidence: 83%

Mesothelioma in Great Britain in 1968-1983.

Jones¹,

Smith²,

Thomas³

1988

Scand J Work Environ Health

View full text Add to dashboard Cite

show abstract

“…The post mortem series may be enriched for atypical cases since the Mayo Clinic medical centre is a tertiary referral institution. Clinical selection of diagnostically challenging cases may have skewed the data although clinicians appear to have little ability in identifying cases that might yield diagnostic surprises [16][17][18][19]. Comfortcare services would be appropriate for patients dying of progressive respiratory failure in the setting of advanced pulmonary fibrosis and these patients may be under represented in a post mortem study.…”

Section: Causes Of Death In Ipf Ce Daniels Et Almentioning

confidence: 99%

Autopsy findings in 42 consecutive patients with idiopathic pulmonary fibrosis

Daniels¹,

Yi²,

Ryu³

2008

Eur Respir J

108

View full text Add to dashboard Cite

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive lung disease that commonly results in respiratory failure and death. However, the cause of death in these patients has not previously been fully defined.The current study reviews the clinical records and pathological findings of 42 consecutive patients with IPF who underwent a post mortem at the Mayo Clinic (Rochester, MN, USA) over a 9-yr period, from January 1996 to December 2004.The median (range) age at post mortem for the patients was 74 (46-98 yrs) yrs, which included 25 (60%) males. A total of 31 (74%) patients died in the hospital. The immediate causes of death were reported as: respiratory (64%), cardiovascular (21%), or noncardiopulmonary (14%). Acute exacerbation of IPF was the most common immediate cause of death (29%). Pneumonia, aspiration and drug-induced lung disease were identified as other causes of respiratory death. Evidence of pulmonary hypertension was present in the post mortem of 19 (45%) patients and was the immediate cause of death in two of these patients. The immediate cause of death was clinically unsuspected in five (12%) patients and IPF was diagnosed post mortem in nine (21%) patients.The majority of patients with idiopathic pulmonary fibrosis who had undergone a post mortem were found to have died from respiratory causes. Acute exacerbation of idiopathic pulmonary fibrosis was found to be the most common cause of death whilst death from the gradual progression of idiopathic pulmonary fibrosis was found to be less common.

show abstract

“…Tem-se demonstrado, no entanto, que mesmo quando essa certeza possa existir, a necrópsia leva a alterações significativas nos diagnósticos anteriormente formulados 8,10,23,28 .…”

Section: Introductionunclassified

“…Como possíveis causas dessa queda temse apontado a excessiva confiança nos diagnós-ticos obtidos pelos sofisticados equipamentos e técnicas laboratoriais, atualmente disponí-veis 8,10,13,20,23 . Outras causas observadas são: a dificuldade de obter-se autorização junto à família, custos elevados e a não implantação sistemática da necrópsia obrigatória, mesmo nos meios universitários****.…”

unclassified

Correlação diagnóstica anatomoclínica. Aferição retrospectiva do diagnóstico clínico em necrópsias

et al. 1989

View full text Add to dashboard Cite

. Aferição retrospectiva do diagnóstico clínico em necrópsias. Rev. Saúde públ., S. Paulo, 23:285-91, 1989. RESUMO:Analisaram-se retrospectivamente 200 necrópsias, correlacionando-se os diagnósticos clí-nicos e anatomopatológicos. Foram consideradas 20 entidades nosológicas para confronto. Os diagnósti-cos não formulados em vida, embora observados na necrópsia (falso negativo), e que apresentaram os maiores percentuais em relação aos respectivos totais de achados necroscópicos, foram: pielonefrite aguda (100%), embolia pulmonar (87,50%), aneurisma dissecante da aorta (66,66%) e broncopneumonia (58,16%). Os diagnósticos formulados em vida que não tiveram confirmação pela necrópsia (falso positivo), e que apresentaram os maiores percentuais em relação aos respectivos totais dos diagnósticos clíni-cos, foram: tuberculose (69,50%), paracoccidioidomicose (57,14%), septicemia (53,13%) e doença de Chagas (44,44%). Houve concordância diagnóstica em 97 (48,50%) dos 200 casos. Em 19 (9,50%) deles o desacordo diagnóstico, se antes verificado, poderia ter implicado alterações do prognóstico. Enfatiza-se a importância da necrópsia para uma adequada correlação anatomoclínica e discute-se os achados em relação a estudos prévios. DESCRITORES: INTRODUÇÃOA necrópsia permite a clínicos e patologistas avaliar, por método direto, os diagnósticos formulados em vida, relacionar os testes clínicos e laboratoriais com os achados anatômicos e avaliar o grau de sucesso do emprego de técnicas cirúrgicas e da utilização de drogas 13,33 .É evidente que o termo "diagnóstico" pode comportar diferentes graus de probabilidade quanto a estar ou não correto, embora tal graduação não seja feita rotineiramente 15 . Tem-se demonstrado, no entanto, que mesmo quando essa certeza possa existir, a necrópsia leva a alterações significativas nos diagnósticos anteriormente formulados 8,10,23,28 .Nos últimos anos, tem-se observado acentuada e progressiva queda do número de necróp-sias que não sejam de interesse médico-legal 40 . Numerosos trabalhos vieram reafirmar a importância da necrópsia como meio de aferição do dignóstico clínico 5

show abstract

A prospective study of 1152 hospital autopsies: I. Inaccuracies in death certification

Cited by 271 publications

References 5 publications

Mesothelioma in Great Britain in 1968-1983.

Mesothelioma in Great Britain in 1968-1983.

Autopsy findings in 42 consecutive patients with idiopathic pulmonary fibrosis

Correlação diagnóstica anatomoclínica. Aferição retrospectiva do diagnóstico clínico em necrópsias

Contact Info

Product

Resources

About