A prospective study of in-hospital mortality and discharge outcome in spontaneous intracerebral hemorrhage

Bhatia, Rohit; Singh, Hariom; Singh, Sumit; Padma, M. V.; Prasad, Kameshwar; Tripathi, Manjari; Kumar, Guresh; Singh, Mamta Bhushan

doi:10.4103/0028-3886.115062

Cited by 66 publications

(89 citation statements)

References 22 publications

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“…Some previous studies found negative results whereas others found a positive association with high serum triglyceride concentrations and risk of stroke 24 . Also we did not find any association of serum blood glucose at the time of presentation with the immediate outcome as shown by other workers also 14,26 . This may be explained by the initial state of stress in such patients leading to high blood sugar levels.…”

Section: Results and Observationssupporting

confidence: 70%

“…The mean age found in our study was 56.1± 2.12 years. Though most studies had found similar mean ages 12,14,15 , European studies have shown higher mean ages in the mid 7 th decades 16 . This discrepancy of age is probably due to lower life expectancy in the Indian population and predisposition to risk factors like diabetes, hypertension etc from a younger age.…”

Section: Results and Observationsmentioning

confidence: 98%

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Prognostic Factors in Intracerebral Hemorrhage: A Hospital Based Prospective Study

Goswami¹,

Sharma²,

Das³

et al. 2016

IJMRP

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Introduction: Intracerebral hemorrhage (ICH), a form of stroke syndrome results from the rupture of an intracerebral vessel leading to the development of a hematoma in the substance of the brain. Incidence rates are particularly high in Asians and Blacks. Attempts are made to prognosticate ICH patients and manage them accordingly. This is particularly important for the socio-economic profile of the patients availing our services. Methods: All together 90 patients of ICH were taken up in this study done in Gauhati Medical College and Hospital during the period from July 2013 to June 2015. Patients were diagnosed on the basis of a thorough medical history, a full neurological examination, standardized blood tests and CT scan of the brain. Prognostication was done on the basis of clinical and radiological findings. Prognosis was assessed as good or bad outcome on the 15th day based on neurological examination. Statistical analysis was done by using the chi-square test, fisher's t-test and student's t-test wherever applicable. Results: In our study 35.55% patients showed bad outcome. Increasing age, low level of consciousness, low GCS score, bilateral limb weakness, high blood pressure, gaze palsies, pupillary abnormalities and CT brain findings of higher volume (>=30 ml) of hematoma, midline shift, intraventricular extension and a high ICH score were associated with bad outcome.

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Section: Results and Observationssupporting

confidence: 70%

Section: Results and Observationsmentioning

confidence: 98%

Prognostic Factors in Intracerebral Hemorrhage: A Hospital Based Prospective Study

Goswami¹,

Sharma²,

Das³

et al. 2016

IJMRP

View full text Add to dashboard Cite

show abstract

“…21 Bhatia et al evaluated 214 patients with ICH and concluded that independent predictors of mortality included a higher hematoma volume, intra ventricular extension, low GCS and ventilatory requirement. 22 Similarly, other variables have been identified such as age, ICH location, mid line shift, blood pressure and pupillary abnormalities. 5,22,23 Review of these studies reveals considerable variability in the factors identified.…”

Section: Outcomementioning

confidence: 99%

“…22 Similarly, other variables have been identified such as age, ICH location, mid line shift, blood pressure and pupillary abnormalities. 5,22,23 Review of these studies reveals considerable variability in the factors identified. This is likely as many factors interact with each other.…”

Section: Outcomementioning

confidence: 99%

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Clinical features and predictors of in hospital mortality in patients with intra cerebral haemorrhage

et al. 2016

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Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population‐based study

et al. 2018

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BackgroundAccurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and identify predictors of severe disability or death following ICH.Materials and methodsRetrospective population‐based study of spontaneous ICH. Clinical and radiological data were obtained from electronic medical records, and functional outcome estimated using the modified Rankin Scale (mRS) before ICH and at 3 and 12 months after ICH.ResultsFour hundred and fifty‐two patients were included (mean age 74.8 years, 45.6% females). Proportion of fatal outcome at 1 week was 22.1%, at 3 months 39.2%, and at 12 months 44.9%. Median mRS score before the ICH was 1 (interquartile range [IQR] 2); for survivors at 3 months, it was 5 (IQR 3); and at 12 months, it was 3 (IQR 2). Independent predictors of severe disability (mRS of 5) or death (mRS of 6) were use of oral antithrombotic drugs (OR 2.2, 95% CI 1.3–3.8, p = 0.04), mRS score before the ICH (OR 1.8, 95% CI 1.4–2.2, p < 0.001), Glasgow Coma Scale (GCS) on admission (OR 8.3, 95% CI 3.5–19.7, p < 0.001), hematoma volume >60 ml (OR 4.5, 05% CI 2.0–10.2, p < 0.001), and intraventricular hematoma extension (OR 1.8, 95% CI 0.8–4.2, p < 0.001).ConclusionIntracerebral hemorrhage is associated with high mortality, and more than one third of survivors end up with severe disability or death 3 months later. Predictors of severe disability or death were use of oral antithrombotic drugs, functional disability prior to ICH, low GCS on admission, larger hematoma volume, and intraventricular hematoma extension.

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A prospective study of in-hospital mortality and discharge outcome in spontaneous intracerebral hemorrhage

Abstract: Low GCS, higher baseline ICH volume, presence of IVH and need for ventilatory assistance are independent predictors of mortality. Most of the patients at discharge were disabled. Surgery did not improve mortality or outcome.

Cited by 66 publications

References 22 publications

Prognostic Factors in Intracerebral Hemorrhage: A Hospital Based Prospective Study

Prognostic Factors in Intracerebral Hemorrhage: A Hospital Based Prospective Study

Clinical features and predictors of in hospital mortality in patients with intra cerebral haemorrhage

Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population‐based study

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