A prospective study on comparative efficacy between two combinational therapies for hypertension

Sumathy, P; Shanmugasundaram, P.; Monika, Manukonda

doi:10.5958/0974-360x.2016.00409.1

Cited by 3 publications

(2 citation statements)

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“…Telah diketahui secara luas bahwa faktor-faktor yang dapat dimodifikasi seperti gaya hidup dan faktor-faktor yang tidak dapat dimodifikasi seperti usia dan jenis kelamin terkait erat dengan tingginya prevalensi hipertensi (Siagian et al, 2021;Gurnita et al, 2020;Dosoo et al, 2019). Obat anti hipertensi digunakan secara luas, namun karena efek samping dan intoleransi obat anti hipertensi oleh pasien hipertensi, kesadaran, manajemen, dan kontrol hipertensi tetap tidak memadai (Wang et al, 2020;Nishad et al, 2019;Sumathy et al, 2018). Pengobatan tekanan darah tinggi dengan menggunakan obat-obatan dapat memberikan efek samping (Andri et al, 2019).…”

Section: Pendahuluanunclassified

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Analisis Bibliometrik Penelitian Pengobatan Herbal Penderita Hipertensi di Indonesia Menggunakan VOS-Viewer

Alifariki

Susanty

Sukurni

2022

JKS

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This study aims to analyze the scope of research on the treatment of hypertension with herbs using a bibliometric approach. The method used is to search the database using the Publish-of-Perish application and then extract the search results using the VOS-viewer. The results show that the minimum number of terms associated with using the VOS-viewer is set to 2 times. After being analyzed, 5 clusters (purple, red, green, blue, and orange) show the relationship between one topic and another. VOS-viewer can display bibliometric mappings in three different visualizations: network, overlay, and density. The keywords that appear the most are hypertension, blood pressure, and the elderly. Through the VOS-Viewer, we analyzed how many articles had been published on herbal remedies for people with hypertension and found that marine herbal ingredients had not been used to treat hypertension in Indonesia for that period. In conclusion, this bibliometric approach is essential to determine novelty in conducting further research by identifying basic themes in each study, the field of knowledge, or research that has been carried out so far. Keywords: Bibliometrics, Herbs, Hypertension, Vos-Viewer

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Section: Pendahuluanunclassified

“…Obat anti hipertensi digunakan secara luas, namun karena efek samping dan intoleransi obat anti hipertensi oleh pasien hipertensi, kesadaran, manajemen, dan kontrol hipertensi tetap tidak memadai (Nishad et al, 2019;Sumathy et al, 2018;Wang et al, 2020). Pengobatan tekanan darah tinggi dengan menggunakan obat-obatan dapat memberikan efek samping.…”

Section: Pembahasanunclassified

Analisis Bibliometrik Penelitian Pengobatan Herbal Penderita Hipertensi di Indonesia Menggunakan VOS-Viewer

Alifariki

Susanty

Sukurni

2022

JKS

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Effectivity Evaluation of Bisoprolol as Additional Hypertension Therapy in Geriatrics with Type 2 Diabetes Mellitus while ongoing with Dual Oral Anti-Hypertension Agent: A Cohort Study

Jaya

Veryanti

Kartika

2021

RJPT

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Background: Bisoprolol is a beta-blocker agent that is widely used as an antihypertensive agent, cardiac rate control, and agent to improve the cardiac ejection fraction. Bisoprolol is commonly added to hypertension therapy in patients with a high risk of heart disease such as hypertension with diabetes. The effectiveness of beta-blocker agents in the treatment of hypertension in geriatrics with diabetes without a history of CVD who are currently using dual therapy is still minimal. Evaluation of this matter needs to be done to complement scientific evidence in the use of bisoprolol in the treatment of hypertension in geriatrics with type 2 diabetes mellitus. Objective: This study aims to compare the effectiveness of bisoprolol as additional therapy in geriatric patients who have diabetes hypertension without CVD history while they are ongoing dual oral antihypertension therapy. Method: A cohort study involving 82 geriatrics was prospectively observed for four weeks. The exposure in this study was the bisoprolol agent. Subjects were divided into two groups, where all patients would undergo dual antihypertensive agents, namely Angiotensin-Receptor-Blocker (ARB) and Calcium-Channel-Blocker (CCB). Reductions in systolic and diastolic blood pressure were observed as primary outcomes, and success in achieving blood pressure goals was observed as a secondary outcome in the study. Result: There was no difference in the decrease in systolic and diastolic blood pressure in the exposure and non-exposure groups (p> 0.05). Judging from the large number of patients who successfully achieved the therapeutic target also showed no significant difference between the exposure and non-exposure groups with systolic and diastolic risk difference (RD) values of 1,091 (CI95%: 0.545-2.184) and 1,222 (CI95%: 0.781-1.913). Conclusion: The addition of bisoprolol agents in geriatric patients with hypertension and diabetes without a history of CVD is not required.

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Medication Adherence and Characteristics of Hypertensive Patients: A Study in Rural Areas

Husnawati

Sukandar

Anggadiredja

2022

RJPT

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Hypertension is a risk factor for cardiovascular disease. Several studies have shown that control of hypertension is still low, and the main reason is the low medication adherence to taking medication for patients, especially in rural areas. It can lead to treatment failure, consequently increasing morbidity and mortality. The purpose of this study is to describe the adherence to medication and observance the characteristics of hypertensive patients in rural areas. A cross-sectional design is used in this study. It was adopted to facilitate the survey of hypertensive patients in rural areas. This research was conducted in several districts in the city of Pekanbaru which is a rural area. The sample consisted of 220 patients with hypertension using the quota sampling technique. The characteristics of patients were measured using a validated questionnaire, and patient adherence was measured by the MGL (Morisky, Green and Levine) adherence scale. The results of the study involving 220 respondents showed that the majority of respondents were women, with an age range of 45-59 years (middle age) and with a low level of education (elementary school graduates). The duration of illnesses was >1-5 years with the majority (50.9%) of patients having a low level of medication adherence. There is no association between patient’s characteristics and adherence. Adherence to taking medication for hypertensive patients in rural areas is low. Pharmacists need to give full attention and think of appropriate interventions to increase patient adherence with medication in rural areas.

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A prospective study on comparative efficacy between two combinational therapies for hypertension

Cited by 3 publications

References 0 publications

Analisis Bibliometrik Penelitian Pengobatan Herbal Penderita Hipertensi di Indonesia Menggunakan VOS-Viewer

Analisis Bibliometrik Penelitian Pengobatan Herbal Penderita Hipertensi di Indonesia Menggunakan VOS-Viewer

Effectivity Evaluation of Bisoprolol as Additional Hypertension Therapy in Geriatrics with Type 2 Diabetes Mellitus while ongoing with Dual Oral Anti-Hypertension Agent: A Cohort Study

Medication Adherence and Characteristics of Hypertensive Patients: A Study in Rural Areas

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