A proton imaging device: Design and status of realization

Sipala, V.; Bruzzi, M.; Bucciolini, M.; Candiano, G.; Capineri, Lorenzo; Cirrone, G.A.P.; Civinini, C.; Cuttone, G.; Presti, D. Lo; Marrazzo, L.; Mazzaglia, E.; Menichelli, D.; Randazzo, N.; Talamonti, Cinzia; Valentini, Stefano

doi:10.1016/j.nima.2009.08.029

Cited by 31 publications

(22 citation statements)

References 5 publications

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“…1. It is made by a tracker, to measure proton trajectories, and a calorimeter, to determine their residual energy [6][7][8][9].…”

Section: The Pct Detector Systemmentioning

confidence: 99%

“…This technique is based on the measurement of both the trajectory of each proton both upstream and downstream the target and the residual proton kinetic energy [3][4][5][6]. The objective of the PRIMA (PRoton IMAging) project, funded by INFN CSN5, has been to prove feasibility of proton CT (pCT), by manufacturing and testing a prototype based on single-proton tracking with microstrip silicon detectors and residual energy evaluation with scintillating crystals [7][8][9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

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The PRIMA (Proton Imaging) collaboration: Status of the development of a proton Computed Tomography Scanner

Bruzzi¹,

Brianzi²,

Bucciolini

et al. 2012

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)

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Abstract-The PRIMA (Proton IMAging) experiment is aimed at developing a proton Computed Tomography (pCT) prototype based on tracking single protons. Approaches to the pCT consist in the use of silicon microstrip detectors to measure the position and direction of individual protons before and after they traverse the phantom, in view to reconstruct the trajectory of each proton, and a calorimeter for measuring particle residual energy. A small prototype was tested, under 62 MeV proton beam at Laboratory Nazionali del Sud, (Catania Italy) and under 180 MeV proton beam at Svedberg Laboratories, Uppsala Universitet, (Uppsala Sweden). Several experiments concerning proton imaging, tomography and radiography, were carried out during these beam tests. Radiographies have been reconstructed with different methods: results show the good performances of the device, with spatial resolution fulfilling the stringent requirements of a pCT device.

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“…1. It is made by a tracker, to measure proton trajectories, and a calorimeter, to determine their residual energy [6][7][8][9].…”

Section: The Pct Detector Systemmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The PRIMA (Proton Imaging) collaboration: Status of the development of a proton Computed Tomography Scanner

Bruzzi¹,

Brianzi²,

Bucciolini

et al. 2012

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)

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“…Noise level can be made negligible if a proper threshold level is chosen. On the basis of electrical front-end board calibration and Monte Carlo simulations about the charge released by protons in silicon, we estimate [12] that it is possible to track protons in the energy range of interest (up to 250MeV) with high efficiency and low noise. In particular, a noise occupancy <10 -6 is obtained as long as (∆V th -V j )>50mV.…”

Section: System Under Testmentioning

confidence: 99%

Development of the Silicon Tracker and of a YAG:Ce Calorimeter for Proton Computed Radiography

Menichelli¹,

Bruzzi²,

Bucciolini³

et al. 2010

Proceedings of 9th International Conference on Large Scale Applications and Radiation Hardness of Semiconductor Detectors — PoS

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The Italian PRoton IMAging (PRIMA) collaboration is developing a Proton Computed Radiography (pCR) apparatus. It should be considered a first step toward Proton Computed Tomography (pCT), which is expected to be a valuable tool to directly measure stopping power distribution of tissues and to improve the quality of treatment planning in proton therapy. The pCR apparatus includes a tracker (based on a set of identical tracker modules, each including a silicon microstrip detector) to measure proton trajectory and a calorimeter (made of four YAG:Ce optically separated crystals) to measure residual energy. Two tracker modules can be assembled in a x-y plane, capable to measure the local coordinates of the incoming proton. The first assembled x-y plane has been recently coupled to the calorimeter, and this system was tested with 62MeV protons. Results from this experiment are presented in this contribution.

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“…A first pCT prototype, based on a silicon tracker and a YAG:Ce calorimeter with a 5x5 cm 2 active area and a 10 kHz data rate, has been developed within the PRIMA collaboration [8][9][10][11]. First results on tomographic reconstruction show that a spatial resolution of the order of 1 mm can be achieved [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Development of a Proton Computed Tomography system for pre-clinical tests

Civinini¹,

Brianzi²,

Bruzzi

et al. 2012

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)

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Abstract-Proton Computed Tomography (pCT) is an imaging method under investigation with the aim to improve the accuracy of treatment planning and patient positioning in hadron therapy. A pCT system should be capable to measure tissue electron density with an accuracy better than 1% and with a spatial resolution better than 1mm. A first apparatus based on a silicon tracker and a YAG:Ce crystal calorimeter, with a 5x5 cm 2 active area, has been already developed by the authors in the framework of the PRIMA (Proton Imaging) collaboration and tested with proton beams with promising results. A second prototype with larger area (5x20 cm 2 ) and improved data acquisition system is being designed. The details about this new prototype will be presented in this work.

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A proton imaging device: Design and status of realization

Cited by 31 publications

References 5 publications

The PRIMA (Proton Imaging) collaboration: Status of the development of a proton Computed Tomography Scanner

The PRIMA (Proton Imaging) collaboration: Status of the development of a proton Computed Tomography Scanner

Development of the Silicon Tracker and of a YAG:Ce Calorimeter for Proton Computed Radiography

Development of a Proton Computed Tomography system for pre-clinical tests

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