A prototype beam delivery system for the proton medical accelerator at Loma Linda

Coutrakon, G.; Bauman, Margaret L.; Lesyna, David; Miller, Daniel W.; Nusbaum, J.; Slater, J.W.; Johanning, J.; Miranda, J.A. Santos; DeLuca, P.M.; Siebers, Jeffrey V.; Ludewigt, B.

doi:10.1118/1.596617

Cited by 41 publications

(26 citation statements)

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“…In a device developed at LLUMC, the beam is stopped in a scintillator block and the output of light as a function of depth is viewed by a CCD camera. 143 The light output is related to the energy loss of the beam, but is not exactly proportional to dose. Therefore, a calibration procedure is required to map the light output into a dose distribution.…”

Section: Iias Range Verificationmentioning

confidence: 99%

“…20 • 304 This type of propeller has been used at the HCL with proton beams, 18 • 305 for helium ions at LBL,2 99 and recently at LLUMC for proton beams. 143 A small propeller for beams less than 2 em in diameter was produced, 306 and used for ocular treatments. In an application outside of radiotherapy, a rangemodulating propeller was developed to deposit primary particles in a predetermined fashion in order to produce a constant yield of radioisotopes with depth.…”

Section: Iib2 Range-modulating Propellersmentioning

confidence: 99%

“…383 A similar multi wire ionization proflle monitor has been used at PARMS 267 and LLU. 143 ( 1 1 reconstruction of the two dimensional image relies on the "filtered back projection" algoritlun. 434 To increase the spatial resolution of MEDUSA without constructing more data channels, another wire chamber has been constructed and the MEDUSA electronics reconfigured.…”

Section: Wire Chambersmentioning

confidence: 99%

“…1 40- 143 The accelerator was designed and built by the Fermi National Accelerator 0 Laboratory. 144 • 145 It is the first dedicated proton accelerator facility built for a hospital.…”

Section: Ibl On-going Proton and Helium-ion Trialsmentioning

confidence: 99%

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Instrumentation for treatment of cancer using proton and light-ion beams

Chu

Ludewigt

Renner

1993

Review of Scientific Instruments

287

186

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Clinical trials using accelerated heavy charged-particle beams for treating cancer and other diseases have been performed for nearly four decades. Recently there have been worldwide efforts to construct hospital-based medically dedicated proton or light-ion accelerator facilities. To make such accelerated heavy charged-particle beams clinically useful, specialized instruments must be developed to modify the physical characteristics of the particle beams in order to optimize their biological and clinical effects. This article reviews the beam modifying devices and associated dosimetric equipment developed specifically for controlling and monitoring the clinical beams.

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Section: Iias Range Verificationmentioning

confidence: 99%

Section: Iib2 Range-modulating Propellersmentioning

confidence: 99%

Section: Wire Chambersmentioning

confidence: 99%

“…1 40- 143 The accelerator was designed and built by the Fermi National Accelerator 0 Laboratory. 144 • 145 It is the first dedicated proton accelerator facility built for a hospital.…”

Section: Ibl On-going Proton and Helium-ion Trialsmentioning

confidence: 99%

See 2 more Smart Citations

Instrumentation for treatment of cancer using proton and light-ion beams

Chu

Ludewigt

Renner

1993

Review of Scientific Instruments

287

186

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“…In this study, the DMG was tested in a pulsed proton therapy environment provided by a synchrotron with a 0.4 s pulse duration and a 2.2 s duty cycle 25. Average dose rates of up to 12 Gy/min, corresponding to an instantaneous dose rate of 66 Gy/min, were tested with stable results.…”

Section: Discussionmentioning

confidence: 99%

Initial testing of a pixelated silicon detector prototype in proton therapy

Wroe

McAuley

Teran

et al. 2017

J Applied Clin Med Phys

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As technology continues to develop, external beam radiation therapy is being employed, with increased conformity, to treat smaller targets. As this occurs, the dosimetry methods and tools employed to quantify these fields for treatment also have to evolve to provide increased spatial resolution. The team at the University of Wollongong has developed a pixelated silicon detector prototype known as the dose magnifying glass (DMG) for real‐time small‐field metrology. This device has been tested in photon fields and IMRT. The purpose of this work was to conduct the initial performance tests with proton radiation, using beam energies and modulations typically associated with proton radiosurgery. Depth dose and lateral beam profiles were measured and compared with those collected using a PTW parallel‐plate ionization chamber, a PTW proton‐specific dosimetry diode, EBT3 Gafchromic film, and Monte Carlo simulations. Measurements of the depth dose profile yielded good agreement when compared with Monte Carlo, diode and ionization chamber. Bragg peak location was measured accurately by the DMG by scanning along the depth dose profile, and the relative response of the DMG at the center of modulation was within 2.5% of that for the PTW dosimetry diode for all energy and modulation combinations tested. Real‐time beam profile measurements of a 5 mm 127 MeV proton beam also yielded FWHM and FW90 within ±1 channel (0.1 mm) of the Monte Carlo and EBT3 film data across all depths tested. The DMG tested here proved to be a useful device at measuring depth dose profiles in proton therapy with a stable response across the entire proton spread‐out Bragg peak. In addition, the linear array of small sensitive volumes allowed for accurate point and high spatial resolution one‐dimensional profile measurements of small radiation fields in real time to be completed with minimal impact from partial volume averaging.

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Radiotherapy: Particle Beams

Becchetti

2006

Encyclopedia of Medical Devices and Instrumentation

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An overview, including historical developments, of various types of particle‐beam radiotherapies is given. This overview also includes electron, proton, neutron, and heavy‐ion radiotherapy. The types of particle accelerators and related apparatus for these are described together with the radiological aspects of each type of particle beam. Possible future developments in the field are outlined.

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A prototype beam delivery system for the proton medical accelerator at Loma Linda

Cited by 41 publications

References 0 publications

Instrumentation for treatment of cancer using proton and light-ion beams

Instrumentation for treatment of cancer using proton and light-ion beams

Initial testing of a pixelated silicon detector prototype in proton therapy

Radiotherapy: Particle Beams

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