The reactions Ca + Ca and Nb 4-Nb at 400 MeV/nucleon have been studied at the Bevalac using the "Plastic Ball" spectrometer. A global analysis of the events shows two nontrivial collective flow effects: the bounceoff of the projectile fragments, and the side-splash of the intermediate-rapidity fragments for the higher-multiplicity Nb + Nb events. Neither effect is seen in a knockon cascade calculation. A simulation with an event-generating statistical model has been done in order to extract the magnitudes of the effects.

Clinical trials using accelerated heavy charged-particle beams for treating cancer and other diseases have been performed for nearly four decades. Recently there have been worldwide efforts to construct hospital-based medically dedicated proton or light-ion accelerator facilities. To make such accelerated heavy charged-particle beams clinically useful, specialized instruments must be developed to modify the physical characteristics of the particle beams in order to optimize their biological and clinical effects. This article reviews the beam modifying devices and associated dosimetric equipment developed specifically for controlling and monitoring the clinical beams.

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