A putative novel strain of Ehrlichia infecting Amblyomma tigrinum associated with Pampas fox (Lycalopex gymnocercus) in Esteros del Iberá ecoregion, Argentina

“…strain La Dormida, and a Ehrlichia sp.) were detected in ticks of the genus Amblyomma [13,[33][34][35][36][37][38][39]. Recently, new Ehrlichia genotypes were described in Ixodes uriae from Chile and Ixodes auritulus from Uruguay [2,14].…”

Section: Discussionmentioning

confidence: 99%

Characterization of “Candidatus Ehrlichia Pampeana” in Haemaphysalis juxtakochi Ticks and Gray Brocket Deer (Mazama gouazoubira) from Uruguay

et al. 2021

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Human ehrlichiosis are scantily documented in Uruguay. The aim of this study was to investigate the presence of Ehrlichia spp. in Haemaphysalis juxtakochi and in a gray brocket deer (Mazama gouazoubira) from Uruguay. The presence of Ehrlichia DNA was investigated in free-living H. juxtakochi in five localities of southeast and northeast Uruguay, as well as blood, spleen, and ticks retrieved from a M. gouazoubira. Ehrlichia spp. DNA was detected in six out of 99 tick pools from vegetation, in the spleen of M. gouazoubira, and in one out of five pools of ticks feeding on this cervid. Bayesian inference analyses for three loci (16S rRNA, dsb, and groEL) revealed the presence of a new rickettsial organism, named herein as “Candidatus Ehrlichia pampeana”. This new detected Ehrlichia is phylogenetically related to those found in ticks from Asia, as well as Ehrlichia ewingii from USA and Cameroon. Although the potential pathogenicity of “Ca. E. pampeana” for humans is currently unknown, some eco-epidemiological factors may be relevant to its possible pathogenic role, namely: (i) the phylogenetic closeness with the zoonotic agent E. ewingii, (ii) the evidence of H. juxtakochi parasitizing humans, and (iii) the importance of cervids as reservoirs for zoonotic Ehrlichia spp. The molecular detection of “Ca. E. pampeana” represents the third Ehrlichia genotype described in Uruguay.

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“…Besides, E. ruminantium as well as several closely related Ehrlichia species, E. ewingii, E. canis and E. muris-like agent have also been proved to infect human [10][11][12][13][14]40]. Although some Ehrlichia species were characterized from ticks or vertebrate animals in recent years [6,[41][42][43][44][45], few studies have been carried out on their pathogenicity to human beings. In this study, due to the far relationship between Candidatus E. hainanensis and other Ehrlichia species, it is di cult to speculate whether it may infect human or not.…”

Section: Discussionmentioning

confidence: 99%

“…Ehrlichia is a genus of obligatory intracellular bacteria belonging to family Anaplasmataceae, order Rickettsiales. Until today, six formally recognized Ehrlichia species [1] and some Candidatus species have been reported [2][3][4][5][6]. They are mainly vectored by ticks and many of them are pathogenic to human or animals.…”

Section: Introductionmentioning

confidence: 99%

Molecular Detection and Identification of “Candidatus Ehrlichia hainanensis”, A novel Ehrlichia Species in Rodents from Hainan Province, China

Zhao

Xue

et al. 2020

Preprint

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Background: Ehrlichia is a genus of Rickettsiales bacteria closely related to human/animal disease and it plays an important role in public health. Naturally they are hosted by mammals such as canines, bovines, wild rodents and vectored by ticks. Results: In this study, we collected 121 rodent samples including 67 Niviventer fulvescens, 27 Rattus tanezumi, 24 Chiromyscus sp., 2 Rattus nitidus and 1 Leopoldamys edwardsi from Hainan province, which consists of the second largest island in China. The presence and genetic diversity of Ehrlichia was evaluated and characterized by amplifying and sequencing the 16S rRNA, groEL and gltA genes. An Ehrlichia was detected in 5 of the 67 Niviventer fulvescens samples (7.46%). The 16S rRNA, groEL and gltA genes show highest 99.20%, 89.87% and 83.86% identity to known Ehrlichia sequences. In the phylogenetic trees they form a distinct cluster from any other species.Conclusions: We propose that this Ehrlichia present a putative novel species nominated as ‘Candidatus Ehrlichia hainanensis’. Its pathogenicity to human is still to be further researched and molecular surveillance in local populations is needed.

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A putative novel strain of Ehrlichia infecting Amblyomma tigrinum associated with Pampas fox (Lycalopex gymnocercus) in Esteros del Iberá ecoregion, Argentina

Cited by 19 publications

References 31 publications

Molecular characterization of novel Ehrlichia genotypes in Ixodes auritulus from Uruguay

Molecular characterization of novel Ehrlichia genotypes in Ixodes auritulus from Uruguay

Characterization of “Candidatus Ehrlichia Pampeana” in Haemaphysalis juxtakochi Ticks and Gray Brocket Deer (Mazama gouazoubira) from Uruguay

Molecular Detection and Identification of “Candidatus Ehrlichia hainanensis”, A novel Ehrlichia Species in Rodents from Hainan Province, China

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