A quicksand called health literacy

Petti, Stefano; Messano, Giuseppe Alessio; Shahinas, Jorida; Polimeni, Antonella

doi:10.1016/j.jds.2013.10.002

Cited by 1 publication

(1 citation statement)

References 3 publications

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“…32 Nevertheless, independent of the primary location of each microbe, it is known that these bacteria are present in saliva. 33,34 The present study lays the foundation for microbial collection from human subjects using the CandyCollect device, and it is important to evaluate the device in subsequent clinical studies for each pathogen of interest.…”

Section: Analytical Chemistrymentioning

confidence: 99%

At-Home Saliva Sampling in Healthy Adults Using CandyCollect, a Lollipop-Inspired Device

McManamen

et al. 2023

Anal. Chem.

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Respiratory infections are common in children, and there is a need for user-friendly collection methods. Here, we performed the first human subjects study using the CandyCollect device, a lollipop-inspired saliva collection device .We showed that the CandyCollect device can be used to collect salivary bacteria from healthy adults using Streptococcus mutans and Staphylococcus aureus as proof-of-concept commensal bacteria. We enrolled healthy adults in a nationwide (USA) remote study in which participants were sent study packages containing CandyCollect devices and traditional commercially available oral swabs and spit tubes. Participants sampled themselves at home, completed usability and user preference surveys, and mailed the samples back to our laboratory for analysis by qPCR. Our results showed that for participants in which a given bacterium (S. mutans or S. aureus) was detected in one or both of the commercially available methods (oral swab and/or spit tubes), CandyCollect devices had a 100% concordance with the positive result (n = 14 participants). Furthermore, the CandyCollect device was ranked the highest preference sampling method among the three sampling methods by 26 participants surveyed (combining survey results across two enrollment groups). We also showed that the CandyCollect device has a shelf life of up to 1 year at room temperature, a storage period that is convenient for clinics or patients to keep the CandyCollect device and use it any time. Taken together, we have demonstrated that the CandyCollect is a user-friendly saliva collection tool that has the potential to be incorporated into diagnostic assays in clinic visits and telemedicine.

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Section: Analytical Chemistrymentioning

confidence: 99%