A randomised study to compare salivary pH, calcium, phosphate and calculus formation after using anticavity dentifrices containing Recaldent® and functionalized tri‑calcium phosphate

Abstract

Aims:The aim of this study was to estimate the pH of saliva, concentration of calcium and inorganic phosphate, and calculus formation before and after usage of Recaldent® (GC Tooth Mousse Plus™), Functionalized Tricalcium Phosphate (3M ESPE ClinPro™ Tooth Crème) and standard dentifrice (Colgate dental cream).Settings and Design:Randomized double-blind study.Materials and Methods:A total of 50 subjects were recruited, the subjects were assessed at their first visit, on the 21st day and on the 42nd day. At the first visit, scaling was carried out and oral hygiene instructions were given. After 21 days, the subjects were given coded dentifrices where the operator and the subjects both were unaware of the type of dentifrice. Clinical parameters assessed were Plaque index, Gingival index, and Calculus index. Salivary samples were obtained to measure calcium, phosphate levels, and pH at 21st day and 42nd day.Statistical Analysis:ANOVA test, t-test, Mann–Whitney test, Kruskal–Wallis test.Results:The mean salivary calcium level and mean salivary phosphate level were higher in Group III (functionalized tricalcium phosphate (3M ESPE ClinPro™ Tooth Creme) as compared to Group II (Recaldent® GC Tooth Mousse Plus™) and Group I (Colgate dental cream) on the 42nd day after using dentifrices, which was statistically significant. This showed that the usage of remineralizing dentifrices led to an increase in the salivary calcium, phosphate, and pH but it did not reach the level of super saturation of the ions caused by elevated pH which could lead to calculus formation.Conclusions:Thought here was a statistically significant increase in salivary calcium and phosphate level in all three groups from baseline to 42nd day, there was no calculus formation.

Ion release and recharge from a fissure sealant containing amorphous calcium phosphate

“…Phosphate ion re-release following recharge at pH 4.0 was significantly higher compared to pH 5.5 and pH 7.0, whereas ion release was lower and did not differ significantly at pH 5.5 and pH 7.0. This may be due to the presence of higher levels of calcium than phosphate in the composition of Tooth Mousse [ 33 , 34 ]. The greater release of calcium than phosphate ions after recharging in the present study was consistent with previous findings [ 3 , 25 , 26 ].…”

“…Each 5 ml of deionized water was stirred with 1.7 g CPP-ACP in a vortex machine (ZX3 Vortex Mixer, VELP Scientifica, Usmate Velate MB, Italy) at a power setting of 3 for 1 min [ 26 ]. Tooth Mousse contains 10% CPP-ACP with 325 mM calcium and 187 mM phosphate [ 34 , 35 ].…”

Effect of ACP-CPP Chewing Gum and Natural Chewable Products on Plaque pH, Calcium and Phosphate Concentration

“…However, calcium concentration was highest in fennel group than CPP-ACP. RECALDENT™ (CPP-ACP) is a revolutionary ingredient that stabilises and delivers high quantities of calcium and phosphate, which are the essential building blocks for teeth [38]. Santhosh BP et al, observed a significantly increase in the salivary calcium and phosphate concentration after chewing CPP-ACP containing chewing gum [8].…”

Analysis of Calsium of Saliva and Relationship with the Calculus Formation

“…Pada penelitian sebelumnya menyatakan pasien penderita periodontitis yang memiliki kandungan kalsium tinggi dalam salivanya memiliki katrang gigi yang tinggi. 6,13 Dari hasil analisis dapat terlihat bahwa beberapa kelompok studi memiliki kadar kalsium yang kecil dengan konsentrasi 14 Pada tabel kelompok pembanding terdapat beberapa sampel yang memiliki konsentrasi diatas rata-rata padahal kalkulus indeksnya dibawah 0,6. Hal ini bisa disebabkan karena responden merawat giginya dengan baik sehingga tidak ada pelikel yang melekat.…”