A randomized controlled study of immediate versus delayed umbilical cord clamping in infants born by elective caesarean section

Bernardo, Giuseppe De; Giordano, Maurizio; Santis, Rita De; Castelli, Paola; Sordino, Desirée; Trevisanuto, Daniele; Buonocore, Giuseppe; Perrone, Serafina

doi:10.1186/s13052-020-00835-2

Cited by 16 publications

(12 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Table 1 illustrates a summary of neonatal outcomes associated with delayed cord clamping performed at the time of cesarean delivery. 29,[33][34][35][36][37]…”

Section: Umbilical Cord Management After Cesarean Deliverymentioning

confidence: 99%

Management of Placental Transfusion to Neonates After Delivery

McAdams

Lakshminrusimha

2021

Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

This review summarizes high-quality evidence supporting delayed umbilical cord clamping to promote placental transfusion to preterm and term neonates. In preterm neonates, delayed cord clamping may decrease mortality and the need for blood transfusions. Although robust data are lacking to guide cord management strategies in many clinical scenarios, emerging literature is reviewed on numerous topics including delivery mode, twin gestations, maternal comorbidities (eg, gestational diabetes, red blood cell alloimmunization, human immunodeficiency virus [HIV] infection, and severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] infection) and neonatal complications (eg, fetal growth restriction, congenital heart disease, and the depressed neonate). Umbilical cord milking is an alternate method of rapid placental transfusion, but has been associated with severe intraventricular hemorrhage in extremely preterm neonates. Data on long-term outcomes are discussed, as well as potential contraindications to delayed cord clamping. Overall, delayed cord clamping offers potential benefits to the estimated 140 million neonates born globally every year, emphasizing the importance of this simple and no-cost strategy.

show abstract

“…Table 1 illustrates a summary of neonatal outcomes associated with delayed cord clamping performed at the time of cesarean delivery. 29,[33][34][35][36][37]…”

Section: Umbilical Cord Management After Cesarean Deliverymentioning

confidence: 99%

Management of Placental Transfusion to Neonates After Delivery

McAdams

Lakshminrusimha

2021

Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

show abstract

“…A randomized controlled trial shows greater hematocrit level in delayed cord clamping group with statistical significance. 7 In a randomized trial demonstrates increase in mean hematocrit level significantly in DCC group. 14 DCC helps in placental blood transfusion.…”

Section: Discussionmentioning

confidence: 96%

“…In an Italian randomized controlled trial consisting of 132 new born shows increase in haematocrit and bilirubin level in DCC group. 7 Physiologic placental transfusion is increased by DCC and this increases 20-30% blood volume and 50% red cell volume in infants (2).AOGO committee opinion says there is small increase in bilirubin level in DCC cases which requires photo therapy 1 . Studies shows no increase in postpartum hemorrhage in delayed cord clamping.…”

Section: Introductionmentioning

confidence: 99%

Effect of Early versus Delayed Cord Clamping on Hematological Parameters of Term Neonates

Ravishankar

Das

Dalal

et al. 2022

Indones J Obstet Gynecol

View full text Add to dashboard Cite

Objectives : To compare the serum bilirubin, hemoglobin, and hematocrit in term infants undergoing delayed cord clamping with early cord clamping after normal and caesarean delivery.Methods : This is a prospective observational study. The neonates in which cord clamping was done within 15 seconds were considered in early cord clamping (ECC) group and where cord clamping was done after 1 minute was considered in delayed cord clamping (DCC) group. The PCV, Hb, serum bilirubin were observed after 48 hours in both the groups and compared.Results : There was statistically significant difference in means of Hb level (p = 0.001) and PCV level (p = 0.001) between DCC and ECC group whereas no statistically significant difference was present in total serum bilirubin level (p = 0.359).Conclusion: There was no significant increase in risk of polycythaemia and hyperbilirubinemia between delayed cord clamping and early cord clamping group rather has beneficial effects in increasing the haemoglobin and haematocrit in the infants.Keywords : delayed cord clamping, early cord clamping, hematocrit, hemoglobin, serum bilirubin, hyperbilirubinemia. Abstrak Tujuan: Untuk membandingkan bilirubin serum, hemoglobin, dan hematoklit pada bayi aterm yang dilakukan delayed cord clamping dan early cord clamping setelah persalinan normal dan seksio sesarea.Metode: Studi ini merupakan studi prospektif. Neonatus yang dilakukan cord clamping dalam 15 detik dikelompokkan pada delayed cord clamping (DCC). PCV, Hb, bilirubin serum diobservasi dalam 48 jam pada kedua kelompok, kemudian dibandingkan.Hasil: Terdapat perbedaan signifikan antara kadar Hb (p = 0,001) dan PCV (p = 0,0010 antara kelompok DCC dan ECC, sedangkan tidak terdapat perbedaan signifikan pada kadar bilirubin serum total (p = 0,3590Kesimpulan: Tidak terdapat peningkatan signifikan polisitemia dan hyperbilirubinemia antara DCC dan ECC.Kata kunci: delayed cord clamping, early cord clapming, hematokrit, hemoglobin, serum bilirubin, hyperbilirubinemia

show abstract

“…It is to be determined whether delayed umbilical cord clamping (DCC) after elective caesarean section (ECS) is of benefit as after eutocic delivery [ 159 , 160 ]. De Bernardo et al [ 159 ] compared DCC at 1 minute versus immediate cord clamping (ICC) in term infants born by ECS. No difference was reported for SpO2, heart rate, temperature both at 5 min and at 10 minutes and glycemia at 120 minutes.…”

Section: Introductionmentioning

confidence: 99%