A Randomized Controlled Study of Prophylactic Use of Umbilical Vein Oxytocin in The Management of Third Stage of Labor.

Manhas, Aranjana

doi:10.9790/0853-0162730

Cited by 4 publications

(6 citation statements)

References 6 publications

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“…(Table 5) Kore et al [12] found significant less blood loss and duration of third stage of labour with intraumblical injection of 10 units of oxytocin than 10 units of IV oxytocin [12]. Manhas et al [13] also found significant less blood loss and duration of third stage of labour with intraumblical injection of 20 units of oxytocin than 2 mg of methylergometrine IV [13]. While Ojha et al [14] found almost no difference in duration of third stage of labour with intraumblical injection of 10 units of oxytocin than 10 units of IM oxytocin and blood loss in third stage was more with intraumblical oxytocin [14].…”

Section: Discussionmentioning

confidence: 99%

Effect of Different Concentration of Intraumblical Injection of Oxytocin and Saline on Third Stage of Labor

Godha¹

2016

OGIJ

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Objectives: The aim of study is to study the different concentration of intraumblical oxytocin saline injection on duration and blood loss of third stage of labor and other parameter. Methods: After considering inclusion and exclusion criteria, cases were divided in to 5 groups. All Women were injected 50 ml of normal saline into umbilical vein immediately after clamping and cutting the cord, in group A without oxytocin, in Group B with 10 units of oxytocin, in group C with 20 unit oxytocin and in group D with 30 unit oxytocin. In group E (control) women were managed conservatively. Duration and amount of blood loss of third stage was noted. Results: There were total 250 women enrolled in the study. A statistically significant reduction in the duration and amount of blood loss of third stage of labor was found in group B compared to group A. On increasing the concentration of oxytocin from 10 IU to 20 IU a slight reduction in mean duration and amount of blood loss of third stage was noted. On further increasing the concentration of oxytocin to 30 IU a statistical significant reduction was present. Conclusion: For active management of third stage intraumblical injection of oxytocin with saline should be promoted.

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Section: Discussionmentioning

confidence: 99%

Effect of Different Concentration of Intraumblical Injection of Oxytocin and Saline on Third Stage of Labor

Godha¹

2016

OGIJ

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“…A period between birth of fetus and delivery of the placenta along with membranes is known as third-stage of labor. [1][2][3] Many times third stage may cause serious complication for both mother and newborn. [4,5] If duration of the third stage exceeds 30 min, it may result in serious risk of postpartum hemorrhage, puerperal infection, and retained placenta.…”

Section: Introductionmentioning

confidence: 99%

“…[4,5] If duration of the third stage exceeds 30 min, it may result in serious risk of postpartum hemorrhage, puerperal infection, and retained placenta. [2] In developing countries, about 25% of maternal mortality is caused by postpartum hemorrhage. [2,6] Retention of the placenta complicates approximately 0.1-3.3% of cases © 2019 IJNR | Published by Innovational Publishers globally, and the risk of recurrence may be as high as 16-23%.…”

Section: Introductionmentioning

confidence: 99%

“…[2] In developing countries, about 25% of maternal mortality is caused by postpartum hemorrhage. [2,6] Retention of the placenta complicates approximately 0.1-3.3% of cases © 2019 IJNR | Published by Innovational Publishers globally, and the risk of recurrence may be as high as 16-23%. [5] The most common causes of these complications are uterine atony, retained placental pieces, coagulation disorders, tears of birth canal, multiple pregnancy, large baby, and age of mother <18 or >40 years.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Intra Umbilical Vein (IUV) Injection of Oxytocic Agents on Outcome of the Third Stage of Labor: A Meta-analysis

Bishnoi¹,

Devi²,

Desai³

2019

IJNR

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Background: Active management of the third stage of labor can easily prevent life-threatening complications of the third stage such as retention of the placenta or its parts, prolonged duration, or postpartum hemorrhage due to atonicity of the uterus. Intraumbilical vein (IUV) injection of oxytocic agents is recommended by some guidelines. Unfortunately, intravenous (IV) oxytocin, although common practice, has not been compared with IUV oxytocic agents in reviews and meta-analysis. Therefore, the main objective of this meta-analysis was to compare the effects of IUV oxytocic agents with intramuscular (IM) and Intravenous (IV) oxytocics on outcomes of the third stage. Materials and Methods: The authors searched randomized and non-randomized control trials through electronic databases which include PubMed, Cochrane Library, and CINAHL and gray literature. The search terms were "umbilical vein injection," "intraumbilical vein injection," "umbilical vein oxytocin," oxytocin, uterotonic, placenta, "retained placenta," labor, "third stage of labor," and "postpartum hemorrhage." Five hundred and ninety-four articles were identified and nine met the inclusion criteria. Data were analyzed by Review Manager 5.3. Results: The pooled results reported that duration of the third stage was 1.23 minutes (95% confidence interval [CI]: 0.41-2.04) shorter, amount of blood loss was 79.09 ml. (95% CI: 46.90-111.28) lesser, and placental separation time was 37.69 seconds (95% CI: 0.58-74.80) shorter in the IUV oxytocin group than the IV oxytocin group. Comparison of IUV oxytocin and IV carbetocin shows no statistically significant differences. In comparison with IM oxytocin, IUV oxytocin also results in 1.13 min (95% CI: 0.28-1.97) shorter duration of the third stage of labor but not shows any significant difference for amount of blood loss. Conclusion: IUV oxytocin is more beneficial for reduction of duration of the third stage of labor, amount of blood loss, and placental separation time than the IV and IM oxytocin.

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“…Manhas A et al conducted a study in which Group 1 received umbilical vein injection of oxytocin. 10 Group 2 received intraumbilical vein saline injection while subjects in group 3 were managed with systemic methylergometrine, 0.2mg intravenous at the delivery of anterior shoulder. …”

mentioning

confidence: 99%

The third stage of labour: to bleed or not to bleed - revised role of intra-umbilical oxytocin in management of third stage of labour

Devi¹,

Bhatnagar²

2017

Int J Reprod Contracept Obstet Gynecol

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Background: Background and Objectives: Postpartum haemorrhage is a single largest and leading cause of maternal morbidity and mortality not only in developing countries but also in developed countries. Every 4 minutes one woman dies from pregnancy or child birth related complications. The present study is an attempt to evaluate the scope of using intraumbilical vs intravenous vs intramuscular injection oxytocin for the active management of third stage of labour.Methods: Six hundred pregnant women at term of a singleton pregnancy with spontaneous onset of labour were included in the study and were randomly divided into 3 groups of 200 women each. Group 1, intraumbilical oxytocin 10U diluted in 10ml of saline, Group 2, intravenous oxytocin 10U and Group 3, intramuscular oxytocin 10U were given after the delivery of baby. The outcome criteria’s with respect to third stage of labour were: duration of the 3rd stage of labour, blood loss by volume, difference in haemoglobin. A significant reduction in duration of third stage (p = 0.001) and blood loss in third stage (p =0.0001) in intraumbilical oxytocin group was found when compared with intravenous oxytocin and intramuscular oxytocin.Conclusions: Intraumbilical oxytocin is better alternative to intramuscular oxytocin and intravenous oxytocinin active management of third stage of labour.

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A Randomized Controlled Study of Prophylactic Use of Umbilical Vein Oxytocin in The Management of Third Stage of Labor.

Abstract: Abstract-The

Cited by 4 publications

References 6 publications

Effect of Different Concentration of Intraumblical Injection of Oxytocin and Saline on Third Stage of Labor

Effect of Different Concentration of Intraumblical Injection of Oxytocin and Saline on Third Stage of Labor

Effect of Intra Umbilical Vein (IUV) Injection of Oxytocic Agents on Outcome of the Third Stage of Labor: A Meta-analysis

The third stage of labour: to bleed or not to bleed - revised role of intra-umbilical oxytocin in management of third stage of labour

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