A randomized controlled trial on the impact of moderate-intensity continuous aerobic exercise on the depression status of middle-aged patients with congestive heart failure

Abdelbasset, Walid Kamal; Alqahtani, Bader A.

doi:10.1097/md.0000000000015344

Cited by 31 publications

(26 citation statements)

References 15 publications

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“…However, these studies observed the high measure of maximal oxygen uptake (VO 2peak ) in mild NAFLD, confirming the vital function of exercise training in the management of this type of patients [12]. Also, other studies provided that physical exercise and dietary control reduce steatosis [13][14][15], liver fat content [16][17][18], depression status [19,20], ventilatory marker dysfunctions [21], and slow down progression of T2DM [22].…”

Section: Introductionmentioning

confidence: 68%

[Retracted] Effect of Moderate‐Intensity Aerobic Exercise on Hepatic Fat Content and Visceral Lipids in Hepatic Patients with Diabesity: A Single‐Blinded Randomised Controlled Trial

Abdelbasset

Elsayed

Nambi

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Objective. Limited studies have assessed the effect of moderate-intensity continuous aerobic exercise on hepatic fat content and visceral lipids in hepatic patients with diabesity. is study was designed to evaluate hepatic fat content and visceral lipids following moderate-intensity continuous aerobic exercise in hepatic patients with diabesity. Design. A single-blinded randomised controlled trial. Methods. irty-one diabetic obese patients with nonalcoholic fatty liver disease were recruited into this study. e patients were randomly classified into exercise and control groups, fifteen patients in the exercise group and sixteen patients in the control group. e exercise group received an 8-week moderate-intensity continuous aerobic exercise program with standard medical treatment, while the control group received standard medical treatment without any exercise program. Hepatic fat content and visceral lipids were assessed before and after intervention at the end of the study. Results. Baseline and clinical characteristics showed a nonsignificant difference between the two groups (p > 0.05). At the end of the intervention, the aerobic exercise showed significant improvements (serum triglycerides and low-density lipoproteins (LDLs), p ≤ 0.002, total cholesterol, p � 0.004, visceral fats, p � 0.016, glycated hemoglobin (HbA1C), p � 0.022, high-density lipoproteins (HDLs), p � 0.038, alanine transaminases (AL), p � 0.044, intrahepatic triglyceride and HOMA-IR, p � 0.046, and body mass index (BMI), p � 0.047), while the control group showed a nonsignificant difference (p > 0.05). e postintervention analysis showed significant differences in favor of the aerobic exercise group (p < 0.05). Conclusions. Moderate-intensity continuous aerobic exercise reduces the hepatic fat content and visceral lipids in hepatic patients with diabesity. Recommendations should be prescribed for encouraging moderate-intensity aerobic exercise training, particularly hepatic patients with diabesity.

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Section: Introductionmentioning

confidence: 68%

[Retracted] Effect of Moderate‐Intensity Aerobic Exercise on Hepatic Fat Content and Visceral Lipids in Hepatic Patients with Diabesity: A Single‐Blinded Randomised Controlled Trial

Abdelbasset

Elsayed

Nambi

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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“…To address the high incidence of depression among HF patients, exercise training may provide a safe solution, as antidepressant medications usually have undesired outcomes 9. Many studies have assessed the effect of aerobic exercise on cardiac disease 10-12, while few studies have explored the influences of exercise training on HF-related depression. Thus, the current study was designed to explore the impacts of low- to moderate-intensity aerobic exercise on depression status in patients with systolic congestive HF, hypothesizing that aerobic exercise training may have beneficial effects on depression status in HF patients.…”

Section: Introductionmentioning

confidence: 99%

Examining the impacts of 12 weeks of low to moderate-intensity aerobic exercise on depression status in patients with systolic congestive heart failure - A randomized controlled study

Abdelbasset

Alqahtani

Elshehawy

et al. 2019

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OBJECTIVES:Psychiatric depression disorder is common in patients with systolic congestive heart failure (HF), and both conditions share underlying pathophysiological mechanisms. The incidence rate of depression disorder has clearly increased with the increase in HF manifestations in recent decades. Depression disorder is considered an independent predisposing factor for hospitalization, disturbed functional performance, and high rates of morbidity and mortality in HF patients. This randomized controlled study was designed to examine the impacts of low- to moderate-intensity aerobic exercise training on depression status in patients with systolic congestive HF.METHODS:A total of 46 systolic congestive HF patients with depression (40-60 years of age) were randomized to receive twelve weeks of mild- to moderate-intensity aerobic exercise plus standard medical treatment (exercise group) or standard medical treatment without any exercise intervention (control group). Depression status was examined using the validated Patient Health Questionnaire-9 (PHQ9) pre- and post-intervention at the end of the study program.RESULTS:No significant differences were observed between the exercise and control groups in demographic data or clinical characteristics (p>0.05). Both study groups showed a significant reduction in depression status at the end of the 12-week intervention (p<0.05). The comparison between the mean values of the depression scores showed significant differences between the two groups after 6 and 12 weeks of the intervention, indicating a greater reduction in depression scores in the exercise group than in the control group (p<0.05).CONCLUSIONS:Twelve weeks of a low- to moderate-intensity aerobic exercise program was safe and effective for reducing depression severity in patients with systolic congestive HF. Low- to moderate-intensity aerobic training should be recommended for cardiac patients, particularly those with HF-related depression.

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“…Given the mediation effect of the functional status, it is important to improve the functional status in patients with HF and depressive symptoms, especially for those with poor nutritional status. Previous studies have confirmed that exercise training was an effective intervention on promoting functional capacity, (Wang, Peng, Li, & Wu, 2019) and it was also useful in reducing the depressive symptoms in patients with HF (Abdelbasset & Alqahtani, 2019). Hence, interventions combining nutrition support and exercise therapies may be effective to reduce depressive symptoms in patients with HF.…”

Section: Discussionmentioning

confidence: 85%

Functional status mediates the association of nutritional status with depressive symptoms in patients with heart failure

Zhang

Zou

Hou

et al. 2020

Journal of Advanced Nursing

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Aims The decline of nutritional status and depressive symptoms are pandemic in heart failure patients and functional status may play a pivotal role between these. This study aimed to determine whether nutritional status is associated with depressive symptoms and whether functional status mediates this relationship in heart failure patients. Design This was a secondary analysis of a cross‐sectional study. Methods The data were collected from November 2015–April 2016. Heart failure patients (N = 254) being hospitalized were included in this secondary analysis. The Depression Sub‐Scale of the Hospital Anxiety and Depression Scale and the Duke Activity Status Index were used to assess patients' depressive symptoms and functional status. The nutritional status of patients was calculated using the Geriatric Nutritional Risk Index. Results In this study, the average scores of depressive symptoms, nutritional status and functional status were 4.91 (SD 3.12), 102.38 (SD 6.57) and 20.58 (SD 8.96) respectively. Out of the 254 patients, 46 patients (18.1%) had significant depressive symptoms (the score of Depression Sub‐Scale of the Hospital Anxiety and Depression Scale ≥ 8) and 55 (21.7%) suffered from malnutrition (the score of Geriatric Nutritional Risk Index ≤ 98). In the multiple regression analyses, nutritional status was negatively associated with depressive symptoms (β = −0.142, p = .02) and functional status mediated the relationship between nutritional status and depressive symptoms. Conclusions Many patients with heart failure have malnutrition and depressive symptoms. Functional status plays a mediating role in the relationship between nutritional status and depressive symptoms. Impact To relieve depressive symptoms in patients with heart failure, it is of importance to improve the functional status, especially for those with poor nutritional status.

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A randomized controlled trial on the impact of moderate-intensity continuous aerobic exercise on the depression status of middle-aged patients with congestive heart failure

Cited by 31 publications

References 15 publications

[Retracted] Effect of Moderate‐Intensity Aerobic Exercise on Hepatic Fat Content and Visceral Lipids in Hepatic Patients with Diabesity: A Single‐Blinded Randomised Controlled Trial

[Retracted] Effect of Moderate‐Intensity Aerobic Exercise on Hepatic Fat Content and Visceral Lipids in Hepatic Patients with Diabesity: A Single‐Blinded Randomised Controlled Trial

Examining the impacts of 12 weeks of low to moderate-intensity aerobic exercise on depression status in patients with systolic congestive heart failure - A randomized controlled study

Functional status mediates the association of nutritional status with depressive symptoms in patients with heart failure

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