A rare case of accelerated gingival overgrowth with high dose amlodipine therapy

Abstract

Introduction: Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immunosuppressive drugs, and a number of calcium channel blockers have been shown to produce similar gingival overgrowth in susceptible patients.
 Case report: We report a case of accelerated drug-induced gingival overgrowth in a 60-year-old hypertensive patient taking amlodipine at a dose of 10 mg.
 Conclusions: Among the calcium channel blockers, nifedipine is most frequently associated with gingival overgrowth. Whereas, there is limited evidence of amlodipine-induced gingival hyperplasia.

Surgical Intervention on Drug-Influenced Gingival Enlargement using Diode Laser Therapy

“…Therefore, the patient must be informed of this tendency and the importance of maintenance of effective oral hygiene as key factors in preventing and managing GE associated with these drugs. Supportive periodontal therapy is crucial to sustaining gingival/ periodontal health, thus preventing the recurrence of GE in the long run [31].…”