2018
DOI: 10.1590/0037-8682-0304-2017
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A rare case of gastric mucormycosis in an immunocompetent patient

Abstract: We report the case of a 23-year-old immunocompetent patient who presented at the emergency department of a Brazilian hospital with epigastric pain and fever. After an investigation that included a computed tomography scan and upper gastrointestinal endoscopy with biopsy, a diagnosis of mucormycosis was established. The patient exhibited favorable progress after surgery and antifungal therapy. Mucormycosis is a rare condition that usually affects immunocompromised patients, with a high mortality rate of up to 8… Show more

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Cited by 11 publications
(7 citation statements)
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“…Similar to the findings of a case report published by Abreu et al . [ 18 ], our positive patient outcomes suggest that increased reporting and awareness of fungal infections in immunocompetent adults may lead to early administration of antifungal drugs, early surgical treatment, and better outcomes. If fungal infection is suspected according to clinical diagnosis, surgical treatment could be considered to eradicate the primary lesion, which may increase the patient's chance of cure.…”
Section: Discussionmentioning
confidence: 98%
“…Similar to the findings of a case report published by Abreu et al . [ 18 ], our positive patient outcomes suggest that increased reporting and awareness of fungal infections in immunocompetent adults may lead to early administration of antifungal drugs, early surgical treatment, and better outcomes. If fungal infection is suspected according to clinical diagnosis, surgical treatment could be considered to eradicate the primary lesion, which may increase the patient's chance of cure.…”
Section: Discussionmentioning
confidence: 98%
“… 2 Unlike other fungal opportunist infections affecting patients with compromised immunity, cancer, or recipients of organ transplant, mucormycosis can occur in patients with diabetes mellitus, 2 , 3 , 4 renal insufficiency, alcoholism, 5 , 6 , 7 or even with an intact immunity system. 8 , 9 , 10 These underlying conditions not only predispose to the disease but also worsen the outcome of patients. Our first patient had diabetes and renal insufficiency as risk factors of mucormycosis.…”
Section: Discussionmentioning
confidence: 99%
“…Zygomycosis was first described as a cause of human disease in 1885 2 . Unlike other fungal opportunist infections affecting patients with compromised immunity, cancer, or recipients of organ transplant, mucormycosis can occur in patients with diabetes mellitus, 2–4 renal insufficiency, alcoholism, 5–7 or even with an intact immunity system 8–10 . These underlying conditions not only predispose to the disease but also worsen the outcome of patients.…”
Section: Discussionmentioning
confidence: 99%
“…The diagnosis is nearly always made by biopsy of the suspected area during or after surgery or endoscopy, or at autopsy [1,2,5,9,10]. Treatment of mucormycosis involves a combination of antifungal therapy with surgical debridement of infected and necrotic tissues [4][5][6]10]. Additionally, early identification and treatment of an underlying predisposing factors, such as diabetes mellitus, immunosuppressive drugs, and neutropenia, chronic alcoholism, and HIV infection is vital to successfully treat invasive mucormycosis [5,8,11].…”
Section: Discussionmentioning
confidence: 99%
“…While any organ system may be affected, rhino-orbital-cerebral and pulmonary infections dominate the literature [3][4][5]. Very few cases of gastrointestinal mucormycosis in an immunocompetent host have been reported [5,6]. The aim of this case report is to highlight the importance of early detection and aggressive medical management of invasive mucormycosis may result in good outcome.…”
Section: Introductionmentioning
confidence: 95%