A Rare Case of Primary Pancreatic Hodgkin Lymphoma

Parikh, Jignesh; Bilal, Mohammad; Tombazzi, Claudio; Jackson, Barbara K.; Dong, Huijun

doi:10.1007/s12029-013-9521-7

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…Patients with primary thyroid lymphoma show a strong female predominance (2-8:1), typically present in the sixth or seventh decade of life, and commonly have a background of lymphocytic thyroiditis [8,16]. Demographic characteristics that are more similar to those of primary thyroid lymphoma than NLPHL are noted in both this case and the one other report of thyroidal NLPHL.…”

Section: Discussionmentioning

confidence: 56%

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Primary Extranodal Nodular Lymphocyte Predominant Hodgkin Lymphoma Involving the Thyroid

Williams

Raess

Braziel

et al. 2019

Head and Neck Pathol

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Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is an uncommon lymphoma that accounts for 3-8% of all Hodgkin lymphomas. NLPHL typically presents as early stage disease with localized peripheral lymphadenopathy. Involvement of extranodal sites at the time of presentation occurs in 6% of cases and most commonly involves the spleen, liver, bone marrow, and Waldeyer ring. Primary extranodal NLPHL is exceedingly rare. We describe the first reported case involving the thyroid and review the six other previously described cases of primary extranodal NLPHL.

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Section: Discussionmentioning

confidence: 56%

“…Several reports and series retrospectively reviewed FNA or core biopsy material following the diagnosis of NLPHL on excisional biopsy or surgical resection. All were non-diagnostic, likely due to the factors previously mentioned [6][7][8][9][10].…”

Section: Discussionmentioning

confidence: 99%

Primary Extranodal Nodular Lymphocyte Predominant Hodgkin Lymphoma Involving the Thyroid

Williams

Raess

Braziel

et al. 2019

Head and Neck Pathol

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“…Data from the European Task Force on Lymphoma found a low incidence of extranodal organ involvement by NLPHL, including liver (3%), bone marrow (1%), lung (1%), skeleton (1%), and other organs (2%) [ 4 ]. Parikh et al have reported a case of NLPHL involving the pancreas [ 5 ], but true gastrointestinal tract involvement is exceedingly rare. Bohn-Sarmiento et al have reported a case of primary NLPHL involving the appendix in a 62-year-old male who presented with acute appendicitis [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Nodular Lymphocyte Predominant Hodgkin Lymphoma of the Ileum

Rangan

Grahn

Feldman

2017

Case Reports in Pathology

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Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is a rare lymphoma derived from germinal center B lymphocytes that typically presents with localized lymph node involvement and can mimic a variety of both reactive and other neoplastic conditions. Extranodal involvement is uncommon in NLPHL and typically occurs in the context of previously documented or synchronous nodal disease. Involvement of the gastrointestinal tract is exceedingly rare. Here, we present the first case to our knowledge of NLPHL involving the ileum that was discovered incidentally on routine screening colonoscopy in an asymptomatic patient. An awareness of the spectrum of clinical presentations, careful morphologic evaluation, and a comprehensive panel of immunohistochemical stains are essential for correct diagnosis of NLPHL presenting in unusual anatomic sites.

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