A Rare Case of Spontaneous Tumor Lysis Syndrome in Small Cell Lung Cancer

Spontaneous tumor lysis syndrome in small cell lung cancer

“…2 While TLS is well established in hematologic malignancies, the prevalence of TLS associated with solid tumors, while it may be higher than previously thought, still remains relatively rare, with much evidence based primarily on case reports. 3,4 To this end, spontaneous TLS in solid tumors is an especially rare occurrence and has been reported in the literature in only a few instances. The first reported case of spontaneous TLS in small cell lung cancer was in 2008, and since that time five other cases have been reported.…”

“…The first reported case of spontaneous TLS in small cell lung cancer was in 2008, and since that time five other cases have been reported. 3,[5][6][7][8] TLS is generally not seen in solid tumors because they have such a low proliferative index. However, small cell lung cancer varies from most solid tumors in that it has a higher rate of cell turnover and may present with a higher degree of tumor burden.…”