A Rare Presentation of Retiform Hemangioendothelioma in the External Auditory Canal

Jothi, Ezhil Arasan; Sundaram, M; Namasivayam, Jeyalakshmidevi; Jothi, Mathivanan

doi:10.1155/2014/715035

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…RH lesions are usually located on the limbs and occasionally on the trunk, with other reports on the back, scalp, perineal area, medial canthus, earlobe, pleura, and jejunum. 4 , 7–10 This is the first report of a lesion arising in the labium majus pudenda.…”

Section: Discussionmentioning

confidence: 82%

Retiform hemangioendothelioma: a rare lesion of the vulva

et al. 2021

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Retiform hemangioendothelioma (RH) is a rare borderline-malignant vascular tumor with specific histological characteristics, usually occurring in the limbs and trunk. We report the case of a 63-year-old woman who presented with a painless, oval nodule that had been growing slowly on her left vulva for 3 years. Magnetic resonance imaging of the pelvic cavity revealed a 4.4- × 2.7- × 1.8-cm cystic lesion in the subcutaneous fat of the left vulva. Resection beyond the macroscopic border was performed. Pathology revealed vascular structures with elongated and narrow arborizing vascular channels that were arranged in a retiform pattern resembling rete testis tissue. Immunohistochemical endothelial staining was positive for CD31, CD34, and Friend leukemia integration-1 (FLI-1). The above features confirmed a diagnosis of RH. There was no local recurrence or metastasis during the 26-month follow-up. RH of the vulva is rare, and its diagnosis is supported by specific histological characteristics and immunohistochemical staining for CD31, CD34, and FLI-1. Wide surgical resection with tumor-free margins is important for a favorable prognosis.

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Section: Discussionmentioning

confidence: 82%

Retiform hemangioendothelioma: a rare lesion of the vulva

et al. 2021

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“…Moreover, it was < 1% in resection specimens. RH has been reported to have low mitotic activity and a low MIB-1 proliferation rate [ 1 , 13 , 14 ]. Our findings indicate that there is heterogeneity in MIB-1 proliferation rates in RH.…”

Section: Discussionmentioning

confidence: 99%

Retiform hemangioendothelioma of the breast in a man with 18F-flurodeoxyglucose accumulation on positron emission tomography: a case report

et al. 2023

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Background Retiform hemangioendothelioma (RH) is a rare, intermediate-grade vascular tumor that often arises in the trunk and extremities. The clinical and radiological features of RH remain largely unknown. Case presentation A male patient in his 70s presented with shortness of breath on exertion, and computed tomography incidentally revealed a tumor in his right breast. Positron emission tomography (PET) revealed moderate 18F-fluorodeoxyglucose (FDG) uptake in the tumor. RH was observed in the resected specimens. Three months after surgery, the patient was free of local recurrence and distant metastasis. Conclusions RH was found in the male breast and was accompanied by FDG uptake on PET. PET may be useful in diagnosing RH. Although metastasis is rare in RH, local recurrence may occur, and careful follow-up is required.

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“…[6] The tumor mainly presents as a slow-growing, ill-defined mass, nodule or plaque involving the skin and subcutaneous tissue of the extremities, with rarer sites being the scalp, pinna, neck, trunk and penis. [278] The patient in this case report was an elderly female presenting with an ill-defined swelling in the gluteal region.…”

Section: Discussionmentioning

confidence: 99%

Retiform hemangioendothelioma of the gluteal region: A case report

Quadri

Saeed

Vasenwala

et al. 2018

Saudi J Med Med Sci

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Retiform hemangioendothelioma is a locally aggressive, rarely metastasizing, low-grade angiosarcoma characterized by intercommunicating vascular channels lined by hobnail or cuboidal endothelial cells, flanked by lymphocyte and hyaline sclerosis. Neoplastic endothelial cells usually express von Willebrand factor, CD31 and CD34, while the lymphocytic infiltrate shows a mixture of CD3+, T and CD20+ B cells. The authors describe a case of a 76-year-old female who presented with a soft, painless, ill-defined mass measuring 9 cm in her right gluteal region for the past 15 years, clinically suggestive of a lipoma. There was no regional lymphadenopathy. The mass was resected and sent for histopathological examination. The slow-growing lesion and the typical histomorphology led to the diagnosis of retiform hemangioendothelioma. The diagnosis was confirmed by immunohistochemistry using CD34 antibody, which strongly stained the endothelial cells. The patient was followed up for 6 months after the surgery and no recurrence was noted.

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A Rare Presentation of Retiform Hemangioendothelioma in the External Auditory Canal

Cited by 3 publications

References 19 publications

Retiform hemangioendothelioma: a rare lesion of the vulva

Retiform hemangioendothelioma: a rare lesion of the vulva

Retiform hemangioendothelioma of the breast in a man with 18F-flurodeoxyglucose accumulation on positron emission tomography: a case report

Retiform hemangioendothelioma of the gluteal region: A case report

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