A rare solitary fibrous tumour of the lacrimal sac presenting as acquired nasolacrimal duct obstruction

Abstract

may reflect the high protein content in the amorphous centre of the lesion, whereas the decreased signal intensity may indicate regions of fibrous tissue and crystals, haemosiderin deposition, or protein immobility. Although inconsistent, the majority of reports state a marked enhancement post-injection of i.v. gadolinium. Our patient did not show this.This case has a very unusual and unexpected diagnosis. The patient was otherwise healthy, with no precipitating cause of hyperuricaemia. His serum urate and renal function were within the normal range and the case was discussed with the physicians.To our knowledge there is no report in the literature of uric acid deposition presenting as a mass in the orbital region.

Solitary Fibrous Tumor of the Conjunctiva

“…5 These include SFTs of the lacrimal gland 6 and the lacrimal sac. 7 Our case is the first reported case, to our knowledge, of SFT of the conjunctiva.…”

Solitary fibrous tumours of the lacrimal sac: A case study and comparison

“…To the best of our knowledge, we have found 4 case reports of solitary fibrous tumour in the lacrimal sac between 1999 and 2017 [2][3][4]. Table 1…”

“…The diagnosis of SFTs is challenging as it does not have distinct histopathological features [2]. Microscopically, SFTs typically consist of ovoid to spindle cells that are haphazardly arranged with varying cellular densities in admixture with stromal collagen bundles [1].…”

Solitary Fibrous Tumor of the Auditory Canal

“…Immunohistochemically, SFT cells are positive for vimentin, CD34, Bcl-2, and CD99. 1,13,14 Smooth muscle actin may be negative or show focal variable staining. 1,13,14 They are negative for S100 protein, epithelial membrane antigen, cytokeratin, CD31, and neurofilament.…”

“…1,13,14 Smooth muscle actin may be negative or show focal variable staining. 1,13,14 They are negative for S100 protein, epithelial membrane antigen, cytokeratin, CD31, and neurofilament. 1,13,14 The broad range of morphologic features shared with other spindle cell neoplasms, along with the unusual extrapleural locations of the tumor, can make the diagnosis of SFT at times challenging.…”