Solitary Fibrous Tumor of the Conjunctiva

Pe’er, Jacob; Maly, Alexander; Deckel, Yael; Frenkel, Shahar

doi:10.1001/archopht.125.3.423

Cited by 13 publications

(6 citation statements)

References 9 publications

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“…These lesions are much less frequent that their counterparts affecting the eyelids, orbit, or conjunctiva. Interestingly, and in spite of their rarity, we found one case of solitary fibrous tumour (previously reported), 2 and one case of 'so-called' malignant fibrous histiocytoma in our series.…”

Section: Fibrous and Fibrohistiocytic Tumoursmentioning

confidence: 42%

“…This case was previously reported in a 29-year-old patient. 2 The lesion existed for at least 1 year. On examination, an elliptical pink mobile mass was detected at the lower fornix and caruncle (Figure 9a).…”

Section: Resultsmentioning

confidence: 99%

“…Rare cases of fibroma, 6,7,8,11 fibrolipoma, 8,11 solitary fibrous tumour, 2 and 'so-called' malignant fibrous histiocytoma 89 have been reported in the caruncle. These lesions are much less frequent that their counterparts affecting the eyelids, orbit, or conjunctiva.…”

Section: Fibrous and Fibrohistiocytic Tumoursmentioning

confidence: 99%

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Lesions of the caruncle: a description of 42 cases and a review of the literature

Levy

Ilsar

Deckel

et al. 2008

Eye

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Lesions of the caruncle are uncommon. On account of the histological composition of the caruncle, which includes, in addition to conjunctiva, hair follicles, sebaceous glands, sweat glands, and accessory lacrimal tissue, the caruncle may develop lesions that may be similar to those found in the skin, conjunctiva, or lacrimal gland. Clinical preoperative diagnosis is very difficult and reached only in about half of the cases. The vast majority of lesions of the caruncle are benign, mainly nevi. Reported malignant lesions are very rare but can be potentially fatal. Although malignancy is clinically overestimated, any suspected malignant lesion should be excised and examined histopathologically by an experienced pathologist. This study presents the clinical and histological data of 42 consecutive caruncular lesions processed at our laboratory and reviews previously reported cases of caruncular lesions.

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Section: Fibrous and Fibrohistiocytic Tumoursmentioning

confidence: 42%

Section: Resultsmentioning

confidence: 99%

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Lesions of the caruncle: a description of 42 cases and a review of the literature

Levy

Ilsar

Deckel

et al. 2008

Eye

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“…In addition to its unique pathologic appearances, most of the deeplysituated orbital SFTs appear to be spaceoccupying le sions presenting with proptosis, while their conjunctival coun terparts have no apparent clinical symptoms in the present case and the previous one. 2 The present case is the second reported case of SFT arising in the conjunctiva. Albeit rare, SFT should be included in the dif ferential diagnosis of conjunctival mass lesions.…”

Section: Discussionmentioning

confidence: 56%

“…To date, about 60 cases of SFT of the eye have been reported with most of them in the orbit, 1 and only one in the conjunctiva. 2 We report here on the second reported case of a SFT arising in the conjunctiva, which clinically and histologically resembles conjunctival nevus, glomangioma, ectopic meningioma, and a hybrid neurogenicmyogenic tumor such as mesectodermal leio myoma.…”

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confidence: 90%

Solitary Fibrous Tumor of the Conjunctiva with Heretofore Undescribed Pathologic Findings

Kim

Ro²,

Shin

et al. 2011

Korean J Pathol

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The specimen consisted of fragmented, darkred, soft hemor rhagic tissue, measuring 0.8×0.4×0.3 cm. The specimen was fixed in 10% formalin. Microscopically, the tumor was well de marcated from the overlying squamous epithelium, with no A 37-year-old female presented with a conjunctival mass discovered 3 years prior. An excisional biopsy revealed a patternless proliferation of round and spindle-shaped cells with an eosinophilic fibrillary cytoplasm and vesicular nuclei with occasional inclusions. Psammoma bodies were arranged around the dilated irregularly-shaped vessels. Differential diagnoses included conjunctival solitary fibrous tumor (SFT), nevus, glomangioma, ectopic meningioma, and mesectodermal leiomyoma. The tumor cells were immunoreactive for CD34, CD99, bcl-2 and vimentin, and were negative for smooth muscle actin, desmin, glial fibrillary acidic protein, S-100 protein, epithelial membrane antigen, and human melanoma black-45. Ultrastructurally, the tumor cells had rough endoplasmic reticulum, free ribosomes, and scattered mitochondria without basal lamina or cellular junctions, which are features of fibroblasts. A diagnosis of SFT was rendered based on the light microscopic, immunohistochemical, and electron microscopic findings. We report here on the second case of a SFT arising in the conjunctiva, which clinically and histologically mimics conjunctival nevus, glomangioma, ectopic meningioma, and a hybrid neurogenic-myogenic tumor such as mesectodermal leiomyoma.

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The Conjunctival Biopsy

Roberts

Thum

2013

Lee's Ophthalmic Histopathology

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Solitary Fibrous Tumor of the Conjunctiva

Cited by 13 publications

References 9 publications

Lesions of the caruncle: a description of 42 cases and a review of the literature

Lesions of the caruncle: a description of 42 cases and a review of the literature

Solitary Fibrous Tumor of the Conjunctiva with Heretofore Undescribed Pathologic Findings

The Conjunctival Biopsy

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