Herein, we report
the design, synthesis, and cyanide-scavenging
behavior of circularly arranged sextuple molecule 4. The six syringaldehyde
units carrying equal number of dimethoxyphenolic moieties projecting
at the periphery make the molecule highly efficient for cleaning up
cyanide from the aqueous solution. The stoichiometric data 1:6 showed
that six units of cyanide interact with one unit of compound 4. The
association constant of the compound for cyanide was 2.5 × 10
4
M
–1
, and its detection limit for cyanide
was 10 nM. The compound was also found to remove cyanide bound to
cytochrome
c
oxidase.