A real time non-invasive cholesterol monitoring system

Abstract

Hypercholesterolemia causes cardiovascular disease which is a disorder of the heart and blood vessels, one of the most significant causes of death in the world, and this needs to be anticipated by monitoring blood cholesterol levels regularly. The current method of monitoring blood cholesterol levels is using invasive technique by collecting blood samples. A simple device is needed to measure blood cholesterol levels that can be done without collecting blood samples. This study aims to develop a non- invasive technique for monitoring blood cholesterol levels using sensors utilizing infrared light absorption in body tissues, in order to simplify measuring blood cholesterol levels regularly for patients with hypercholesterolemia. The application of a non-invasive technique focused on developing a total blood cholesterol monitoring device using an infrared sensor with IR LED - 940nm wavelength as a transmitter. A photodiode was used as a detector with the wavelength range of 400-1100 nm and a microcontroller as the minimum system for controlling the value of the output voltage in the form of digital data and then converted onto total blood cholesterol. The measurement results using non-invasive technique was compared to the results using invasive technique.

Tear Fluid as a Matrix for Biomonitoring Environmental and Chemical Exposures

“…Further evidence of lipids re ecting internal exposures is provided by researchers from Wearable Electronics Lab at Yonsei University, who have reported a correlation between tear uid and blood cholesterol levels using a wearable contact lens biosensor 115 . High lipid diets, including high cholesterol diets, are associated with atherosclerosis, hypertension, and an increased likelihood of cardiovascular arrest; as such, it is currently important to develop noninvasive and continuous blood-cholesterol monitoring techniques 116 .…”

Perancangan dan Implementasi Alat Pendeteksi Dini Penyakit Jantung Koroner

“…Budi Nur Iman dkk. : Perancangan dan Implementasi Alat Pendeteksi Dini Penyakit Jantung Koroner kadar kolesterol total dan tekanan darah menjadi penyebab terjangkitnya penyakit jantung koroner [4]. Kadar kolesterol total yang baik adalah kurang dari 200mg/dl [5].…”

“…Pada penelitian sebelumnya telah dibuat alat ukur kadar kolesterol secara non-invasif menggunakan sensor DS-100A yang mampu menghasilkan perubahan tegangan terhadap kadar kolesterol pada darah [7]. Selain itu terdapat pula penelitian deteksi kadar kolesterol total menggunakan IR LED dengan panjang gelombang 940nm sebagai transmitter dan photodiode sebagai detektor dengan panjang gelombang antara 400nm hingga 1100nm dengan output tegangan yang akan dikonversi ke dalam nilai kadar kolesterol [4]. Pada perkembangannya memungkinkan dibuat sebuah alat ukur tekanan darah secara otomatis dengan menggunakan sensor tekanan MPX5050GP dengan menggunakan metode osilometri [8].…”

“…Pengukuran kadar kolesterol menggunakan LED dan photodioda. LED berfungsi sebagai trasmitter atau pemancar cahaya, sedangkan photodiode berfungsi sebagai receiver atau penerima cahaya [4]. Cahaya yang diterima oleh photodiode diterima oleh mikrokontroler berupa nilai ADC.…”