A reappraisal of vascular anatomy of the parathyroid gland based on fluorescence techniques

Sadowski, Samira M.; Fortuny, Jordi Vidal; Triponez, Frédéric

doi:10.21037/gs.2017.07.10

Cited by 45 publications

(35 citation statements)

References 48 publications

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“…In addition, ICG has most recently emerged as a technique for assessing the vascularization of the parathyroid glands, which seems to be closely correlated with parathyroid function, after thyroid resection [22,[32][33][34][35][36]. From a technical point of view, the protocols and doses of dye used for ICG angiography differ from center to center, with the best dosage still under debate.…”

Section: Discussionmentioning

confidence: 99%

“…Lastly, although ICG angiography is still "passive" because it only allows for the evaluation of parathyroid glands after surgical resection, nonetheless research that focuses on making these new imaging tools "active" in order to reduce the extent of thyroid resection, and thereby decreasing (ideally to zero) the rates of post thyroidectomy hypoparathyroidism, is very promising [36].…”

Section: Icg Scorementioning

confidence: 99%

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Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands

Demarchi

Karenovicŝ

Bédat

et al. 2020

JCM

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Fluorescence imaging is a well-known method for both the in vivo and in vitro identification of specific cells or tissues. This imaging tool is gaining importance in the intraoperative detection and preservation of parathyroid glands during endocrine surgery owing to the intrinsic properties of parathyroid tissue. The aim of this paper is to provide an overview of the basics of the technology, its history, and the recent surgical intraoperative applications of near-infrared imaging methods. Moreover, a literature review of the utilization of fluorescence devices in thyroid surgery suggests that the use of near-infrared imaging seems to be beneficial in reducing postoperative hypoparathyroidism, which is one of the most frequent complications of thyroid surgery.

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Section: Discussionmentioning

confidence: 99%

Section: Icg Scorementioning

confidence: 99%

Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands

Demarchi

Karenovicŝ

Bédat

et al. 2020

JCM

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“…These two properties make ICG ideal for angiography as it remains entirely in the blood circulation with a short lifetime. ICG has been widely used in fluorescence-guided surgery applications, such as for macular degeneration, fluorescence cholangiography, perfusion assessment of gastrointestinal anastomoses, real-in vivo 34: 23-32 (2020) time lymph node mapping, adrenalectomy, coronary artery bypass graft, and tissue flap reconstructions (3,9). ICG fluoresces at about 800 nm with a maximum absorption spectrum of 805 nm and reemission at 835 nm when excited by a light/laser at a wavelength in the NIR spectrum.…”

Section: Discussionmentioning

confidence: 99%

“…However, there are significant differences in study design, inclusions, definitions and management protocol between reported studies (6)(7)(8). Additionally, there is no consensus regarding the standardization of technical details, while a universal objective scoring system is missing, thus, the correlation between intraoperative findings and postoperative outcomes remains unclear (9). Taking all this into account, we performed a pooled analysis of the available literature on this important yet controversial topic and review the utility of this clinically promising technique in PG detection and viability during total or near-total thyroidectomy (T-NT) or PTX.…”

Section: Angiography For the Identification Of The Parathyroid Glandsmentioning

confidence: 99%

Intraoperative Indocyanine Green (ICG) Angiography for the Identification of the Parathyroid Glands: Current Evidence and Future Perspectives

Spartalis¹,

Ntokos²,

Γεωργίου³

et al. 2019

In Vivo

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Background/Aim: Recently, indocyanine green (ICG) fluorescence imaging has been used for the identification of the parathyroid glands (PG) during thyroid and parathyroid surgery. However, an overall consensus on the optimal technique, the dosage, the timing of the ICG administration and finally its interpretation and clinical usefulness is still lacking evidence. The aim of this review is to investigate the use of ICG angiography during thyroidectomy and/or parathyroidectomy for identification as well as for the perfusion integrity of the parathyroid glands. Materials and Methods: The PubMed database was systematically searched for publications regarding intraoperative ICG imaging in patients that undergo thyroidectomy or parathyroidectomy. Results: Eighteen publications reporting on 612 patients, namely 71 parathyroidectomy and 541 thyroidectomy patients met the inclusion criteria. Eleven publications reported the use of ICG 23 This article is freely accessible online.

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“…CND is recommended for patients with PTC according to most of the current guidelines on the management of thyroid cancers(3, 4). Anatomically, the location of parathyroid glands (PGs), particularly the lower two, are variable, which results in high risk of accidentally removal during thyroidectomy, particularly when a CND is combined(40). Removal of PGs often leads to transient or permanent hypoparathyroidism and hypocalcemia, which has an adverse impact on the quality of life of the patients.…”

Section: Discussionmentioning

confidence: 99%

The Role of Carbon Nanoparticle in Lymph Node Detection and Parathyroid Gland Protection during Thyroidectomy- a Meta Analysis

et al. 2019

Preprint

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10Objective: To assess the efficiency of the carbon nanoparticles (CNs) in lymph node identification 11 and parathyroid gland protection during thyroidectomy. 12 Methods: A systematic literature search for relevant literatures published up to December 2018 in 13 PubMed, Embase, Web of Science and Cochrane Library was performed. Both English and Chinese 14 literatures were retrieved and analyzed. Randomized controlled trials or nonrandomized controlled 15 trials on the use of CNs during thyroidectomy were enrolled in this study. The primary outcomes 16 included the number of lymph nodes harvesed, rate of lymph nodes involvement, and the rates of 17 accidental parathyroidectomy, hypoparathyroidism, and hypocalcemia. Weighted mean differences 18 (WMDs), odds ratios (ORs) and risk differences (RDs) were calculated for the dichotomous 19 outcome variables. Between-study heterogeneity was tested using the Q tests and the I 2 statistics. 20All analyses were performed using Review Manager (version 5.3.5). 21Results: 25 studies comprising 3266 patients were included in this analysis. The total number of 22 lymph nodes harvested in the groups of carbon nanoparticles was significant higher than that in the 32 Conclusions:The application of CNs for thyroidectomy results in higher number of lymph node 33 harvested and better parathyroid gland protection during initial surgery and reoperation for thyroid 34 cancer. 35

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A reappraisal of vascular anatomy of the parathyroid gland based on fluorescence techniques

Cited by 45 publications

References 48 publications

Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands

Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands

Intraoperative Indocyanine Green (ICG) Angiography for the Identification of the Parathyroid Glands: Current Evidence and Future Perspectives

The Role of Carbon Nanoparticle in Lymph Node Detection and Parathyroid Gland Protection during Thyroidectomy- a Meta Analysis

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