A Reconstruction Algorithm of Magnetoacoustic Tomography With Magnetic Induction for an Acoustically Inhomogeneous Tissue

Zhou, Lian; Zhu, Shanan; He, Bin

doi:10.1109/tbme.2014.2304494

Cited by 19 publications

(3 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Acoustic reflections due to the acoustic impedance heterogeneity will also create extra “noisy” acoustic sources that are not related to the electrical properties of the imaging objects and may provide extra information of the mechanical properties if modeled correctly in the future. Some recent studies have started to tackle this problem, and initial theoretical and computer simulation studies have demonstrated the feasibility to better quantify electrical conductivity in MAT-MI by mapping the inhomogeneous acoustic speed from ultrasound transmission tomography (Zhou et al , 2014). In addition, MAT-MI image reconstruction algorithms that can take into account the conductivity anisotropy need to be developed in the future, as electrical conductivity anisotropy in certain tissue types such as muscles and neural fibers has been suggested to change the MAT-MI signal significantly (Brinker and Roth, 2008; Li et al , 2013).…”

Section: Challenges and Future Directionsmentioning

confidence: 99%

“…Though demonstrated in computer simulation, such simplified approaches can hardly be applied on experimentally collected MAT-MI signal, which is dominated by conductivity gradient sources. As mentioned in some later theoretical studies (Kunyansky 2012, Zhou et al 2014, if it is possible to rotate the static magnetic field B 0 , e.g. setting it to three orthogonal directions, while keeping the magnetically induced eddy current in the conductive tissue sample the same, one may be able to get a good estimation of the curl of the eddy current ∇ × J and further estimate the electrical conductivity.…”

Section: Mapping Conductivity Through Mapping Mat-mi Acoustic Sourcementioning

confidence: 99%

See 1 more Smart Citation

Magnetoacoustic tomography with magnetic induction (MAT-MI) for imaging electrical conductivity of biological tissue: a tutorial review

2016

Phys. Med. Biol.

View full text Add to dashboard Cite

Magnetoacoustic tomography with magnetic induction (MAT-MI) is a noninvasive imaging method developed to map electrical conductivity of biological tissue with millimeter level spatial resolution. In MAT-MI, a time-varying magnetic stimulation is applied to induce eddy current inside the conductive tissue sample. With the existence of a static magnetic field, the Lorentz force acting on the induced eddy current drives mechanical vibrations producing detectable ultrasound signals. These ultrasound signals can then be acquired to reconstruct a map related to the sample’s electrical conductivity contrast. This work reviews fundamental ideas of MAT-MI and major techniques developed in these years. First, the physical mechanisms underlying MAT-MI imaging are described including the magnetic induction and Lorentz force induced acoustic wave propagation. Second, experimental setups and various imaging strategies for MAT-MI are reviewed and compared together with the corresponding experimental results. In addition, as a recently developed reverse mode of MAT-MI, magneto-acousto-electrical tomography with magnetic induction (MAET-MI) is briefly reviewed in terms of its theory and experimental studies. Finally, we give our opinions on existing challenges and future directions for MAT-MI research. With all the reported and future technical advancement, MAT-MI has the potential to become an important noninvasive modality for electrical conductivity imaging of biological tissue.

show abstract

Section: Challenges and Future Directionsmentioning

confidence: 99%

Section: Mapping Conductivity Through Mapping Mat-mi Acoustic Sourcementioning

confidence: 99%

Magnetoacoustic tomography with magnetic induction (MAT-MI) for imaging electrical conductivity of biological tissue: a tutorial review

2016

Phys. Med. Biol.

View full text Add to dashboard Cite

show abstract

“…Also, as compared to traditional ultrasound imaging, the MAT method has lower ultrasound attenuation due to the tissue from the reduced travel path of the acoustic waves from the MNPs embedded in tissue to the sensing transducer leading to improved imaging depth. The MAT method is similar to magneto acoustic tomography with magnetic induction (MAT-MI), which is being explored for high resolution bioimpedance imaging [7][33][34]. With MAT-MI a combination of pulsed and static magnetic fields are used to generate acoustic fields by using Lorentz force; this acoustic field can be used to estimate the high resolution conductivity distribution of the tissue.…”

Section: Introductionmentioning

confidence: 99%

Magneto acoustic tomography with short pulsed magnetic field for in-vivo imaging of magnetic iron oxide nanoparticles

Mariappan

Shao

Jiang

et al. 2016

Nanomedicine: Nanotechnology, Biology and Medicine

View full text Add to dashboard Cite

Nanoparticles are widely used as contrast and therapeutic agents. As such, imaging modalities that can accurately estimate their distribution in-vivo are actively sought. We present here our method Magneto Acoustic Tomography (MAT), which uses magnetomotive force due to a short pulsed magnetic field to induce ultrasound in the magnetic nanoparticle labeled tissue and estimates an image of the distribution of the nanoparticles in-vivo with ultrasound imaging resolution. In this study, we image the distribution of superparamagnetic iron oxide nanoparticles (IONP) using MAT method. In-vivo imaging was performed on live, nude mice with IONP injected into lymph node derived cancer of the prostate tumors induced over the hind limb of the mice. Our experimental results indicate that the MAT method is capable of imaging the distribution of IONPs in-vivo. Therefore, MAT could become an imaging modality for high resolution reconstruction of MNP distribution in the body.

show abstract

Novel reconstruction algorithm of magnetoacoustic tomography based on ring transducer array for acoustic speed inhomogeneous tissues

Wang

Liu

Chen³

et al. 2020

Medical Physics

View full text Add to dashboard Cite

Purpose Magnetoacoustic tomography with magnetic induction (MAT‐MI) is a technique that utilizes the acoustic signals induced by magnetic stimulation to reconstruct the electrical impedance distribution in biological tissues. Most algorithms ignored the fact that acoustic properties in human tissues are heterogeneous, which lead to distortion and blurring of small reconstructed objects. In this study, a novel algorithm is proposed for exact reconstruction of the sound source distribution in acoustic heterogeneous tissues. Methods Based on the ring transducer array, we develop an algorithm which combines algebraic reconstruction technique (ART) and time reversal method. Different to existing reconstruction methods, the ultrasonic transmission tomography (UTT) and the MAT‐MI can be completed in same system, which decreases the system complexity. The sound velocity distribution is reconstructed with the ART so that the propagation time of the magnetoacoustic signals in the heterogeneous tissue is corrected. And then, the sound source image is reconstructed based on the time reversal method from new sound pressure data. Both numerical simulations and phantom experiments are established to validate the proposed method. Results Compared with the results without consideration of the variation on acoustic speed, sound sources reconstructed by our method are more consistent with the model in terms of size and shape. Conclusions The novel algorithm can be used to reconstruct the high‐accuracy image of MAT‐MI sound source in the sound velocity inhomogeneous media. In addition, this method is applicable to scenarios that the prior knowledge of the imaging targets is unknown. The signal acquisition time of MAT‐MI in acoustically heterogeneity media is greatly reduced due to the introduction of ring transducer array into the imaging system. Therefore, our method will promote the application of MAT‐MI in noninvasive early diagnosis of tumor for preclinical study.

show abstract

A Reconstruction Algorithm of Magnetoacoustic Tomography With Magnetic Induction for an Acoustically Inhomogeneous Tissue

Cited by 19 publications

References 41 publications

Magnetoacoustic tomography with magnetic induction (MAT-MI) for imaging electrical conductivity of biological tissue: a tutorial review

Magnetoacoustic tomography with magnetic induction (MAT-MI) for imaging electrical conductivity of biological tissue: a tutorial review

Magneto acoustic tomography with short pulsed magnetic field for in-vivo imaging of magnetic iron oxide nanoparticles

Novel reconstruction algorithm of magnetoacoustic tomography based on ring transducer array for acoustic speed inhomogeneous tissues

Contact Info

Product

Resources

About