2013
DOI: 10.1002/cnm.2559
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A reduced computational and geometrical framework for inverse problems in hemodynamics

Abstract: SUMMARYThe solution of inverse problems in cardiovascular mathematics is computationally expensive. In this paper we apply a domain parametrization technique to reduce both the geometrical and computational complexity of the forward problem, and replace the finite element solution of the incompressible NavierStokes equations by a computationally less expensive reduced basis approximation. This greatly reduces the cost of simulating the forward problem. We then consider the solution of inverse problems in both … Show more

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Cited by 104 publications
(112 citation statements)
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“…• In [147], the authors use the reduced basis method (section 4.3) to create a reduced model of nonlinear viscous flows with varying Young's modulus and varying geometrical parameters, representing arterial wall shape in a fluidstructure interaction problem with a stenosis and a shape optimization process of an arterial bypass. They achieve a reduction from a full model of state dimension 35,000 to a reduced model of state dimension 20 while maintaining accuracy levels of O(10 −2 ) in the vorticity estimates for the shape optimization process, and a reduction from a full model of state dimension 16,000 to a reduced model of state dimension 8 while maintaining accuracy levels of O(10 −2 ) in the viscous energy dissipation estimates for the fluid-structure interaction simulation in presence of a stenosis in the arterial branch.…”
Section: Parametric Model Reduction In Actionmentioning
confidence: 99%
“…• In [147], the authors use the reduced basis method (section 4.3) to create a reduced model of nonlinear viscous flows with varying Young's modulus and varying geometrical parameters, representing arterial wall shape in a fluidstructure interaction problem with a stenosis and a shape optimization process of an arterial bypass. They achieve a reduction from a full model of state dimension 35,000 to a reduced model of state dimension 20 while maintaining accuracy levels of O(10 −2 ) in the vorticity estimates for the shape optimization process, and a reduction from a full model of state dimension 16,000 to a reduced model of state dimension 8 while maintaining accuracy levels of O(10 −2 ) in the viscous energy dissipation estimates for the fluid-structure interaction simulation in presence of a stenosis in the arterial branch.…”
Section: Parametric Model Reduction In Actionmentioning
confidence: 99%
“…Ad hoc reduced order modelling techniques have recently been proposed for optimal flow control problems [104,108,121], optimal shape design of devices related with fluid flows [6,58,23,88], and the treatment of fluid-structure interaction problems [76,78].…”
Section: Discussionmentioning
confidence: 99%
“…We do not provide any detail about the evaluation of these quantities; the interested reader can refer, for instance, to [76,87,94,124].…”
Section: Certification Of Roms For the Steady Navier-stokes Equationsmentioning
confidence: 99%
“…The integration of the RBF parametrization technique within the reduced basis framework, as well as its application to blood flow simulation on geometries reconstructed from patient data, looks promising in its flexibility and ability to express a variety of shape deformations. Further elements that may be explored deal with the uncertainty quantification [5] and/or robust optimization and control problems [6] for patient-specific scenarios. …”
Section: Discussionmentioning
confidence: 99%
“…In the end, at the outer level a suitable iterative procedure for the optimization is performed. A brief presentation of the whole framework can be found in [8], while a more detailed analysis has been recently addressed in [5,6].…”
Section: A General Strategy For Reduction In Shape Dependent Flowsmentioning
confidence: 99%