A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection

Luo, Meiju; Wang, Qi

doi:10.1016/j.aej.2020.12.041

Cited by 17 publications

(6 citation statements)

References 33 publications

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“…Luo et al reported a new method for sensing dissolved oxygen with good sensitivity and linearity [ 82 ]. Commonly, optical-fibre sensing of dissolved oxygen is achieved by the fluorescence quenching effect of oxygen molecules with embedded fluorescent molecules in a gel or polymer matrix [ 83 ].…”

Section: Advances In Optical-fibre-based Biomedical Photonic Sensorsmentioning

confidence: 99%

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Ochoa

Algorri

Roldán-Varona

et al. 2021

Sensors

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In this invited review, we provide an overview of the recent advances in biomedical photonic sensors within the last five years. This review is focused on works using optical-fibre technology, employing diverse optical fibres, sensing techniques, and configurations applied in several medical fields. We identified technical innovations and advancements with increased implementations of optical-fibre sensors, multiparameter sensors, and control systems in real applications. Examples of outstanding optical-fibre sensor performances for physical and biochemical parameters are covered, including diverse sensing strategies and fibre-optical probes for integration into medical instruments such as catheters, needles, or endoscopes.

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Section: Advances In Optical-fibre-based Biomedical Photonic Sensorsmentioning

confidence: 99%

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Ochoa

Algorri

Roldán-Varona

et al. 2021

Sensors

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“…The basic principle of fiber-optic SPR sensor is based on the SPR [32], which usually occurs at the dielectric and metal interface having opposite signs of real parts of their dielectric constants. A schematic diagram of the sensing structure of fiber-optic SPR probe is depicted in the inset of figure 1.…”

Section: Principle Of Operationmentioning

confidence: 99%

“…The other two ports of Y-type fiber coupler were connected to the spectrometer and the light source, respectively. The input light firstly propagate through the Y-typed fiber and then enters into the SPR sensor, the evanescent wave generated around the sensing region, when wave vector of evanescent wave matches that of plasmon on metal film surface, resulting in SPR phenomenon [32]. Once the light is coupled into the SPW, to generate energy transfer, it will decay immediately and generate a dip at resonant wavelength.…”

Section: H 2 S Gas Measurement Experimentsmentioning

confidence: 99%

Highly sensitive fiber-optic SPR sensor with surface coated TiO₂/MWCNT composite film for hydrogen sulfide gas detection

Chen¹,

Lan²,

Wang³

et al. 2021

J. Phys. D: Appl. Phys.

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Hydrogen sulfide (H2S) gas poses a severe effect on the respiratory system of the human body and ambient environment, necessitating development of on-line H2S gas sensors with high performance for safety and health concerns. Here, we proposed a fiber-optic surface plasmon resonance (SPR) sensor for H2S detection employing TiO2nanoparticles and multilayer carbon nanotubes composite (TiO2/MWCNT) as sensing film, featuring desirable advantages of highly sensitivity, selectivity, and real-time detection. Benefiting from special structure and large specific surface area of MWCNTs, the adsorption capacity of sensing surface to gas molecules can be significantly enhanced. Moreover, the high carrier mobility of MWCNTs can further promote the charge transfer between TiO2 and H2S. These unique features of TiO2/MWCNT composite film result in an obvious improvement of sensitivity for H2S detection. Experimental results show that the maximum sensitivity of 21.76 pm/ppm and detection limit of 0.2 ppm can be obtained by appropriately optimizing the componential constitutions of TiO2/MWCNT composite. Such detection limit is strikingly lower than the threshold concentrations in workplace set by Federal Institute for Occupational Safety (10 ppm). In addition, the favorable selectivity, response/recovery times, repeatability and stability were demonstrated as well. This facile and cost-effective work provides a novel strategy for constructing high performance H2S gas sensor with fast response and real-time detection, which has prospective application in the fields of human health and environmental conservation.

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“…4,5 Notably, several optical techniques have been developed recently to detect oxygen in Hb. [6][7][8] Optical science contains a wide array of technologies, including telecommunications, 9-11 solar cells, 12,13 astronomy devices, 14,15 and surface plasmon-based devices [16][17][18] that among them, sensing applications, including biosensors, are of great importance. Sensing technologies are crucial as diagnostic tools by translating signals from biological systems into electrochemical, electrical, magnetic, or optical indicators.…”

Section: Introductionmentioning

confidence: 99%

Theoretical study of biophotonics sensor based on one-dimensional photonics crystal for the detection of dissolved oxygen in hemoglobin

Pourhassan,

Abdol,

SaeidNahaei

et al. 2024

Opt. Eng.

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The vital gases carry through the hemoglobin; hence, the detection and analysis of hemoglobin concentration are crucial in the physiology processes. In this context, we introduce a biosensor based on a one-dimensional photonic crystal with a defect layer for oxygen sensing in hemoglobin. In this innovative approach, hemoglobin is the defect layer and its refractive index changes with oxygen dissolution. The variation of the refractive index leads to a shift in the transmission spectrum, which can be utilized to distinguish between oxygenated and deoxygenated hemoglobin. The theoretical investigation of transmission spectra using the transfer matrix method reveals that both hemoglobin states can be effectively distinguished. The proposed sensor exhibits remarkable sensitivity, particularly with the optimum structure featuring a defect layer thickness of 12 μm, seven layers, and an incident angle (θ) of 81 deg, providing a sensitivity of 1510.5 nm/RIU. These findings underscore the high-performance potential of our sensor in the region of oxygen sensing in biology, particularly in medical applications.

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A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection

Cited by 17 publications

References 33 publications

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Highly sensitive fiber-optic SPR sensor with surface coated TiO₂/MWCNT composite film for hydrogen sulfide gas detection

Theoretical study of biophotonics sensor based on one-dimensional photonics crystal for the detection of dissolved oxygen in hemoglobin

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A reflective optical fiber SPR sensor with surface modified hemoglobin for dissolved oxygen detection

Cited by 17 publications

References 33 publications

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Highly sensitive fiber-optic SPR sensor with surface coated TiO2/MWCNT composite film for hydrogen sulfide gas detection

Theoretical study of biophotonics sensor based on one-dimensional photonics crystal for the detection of dissolved oxygen in hemoglobin

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Highly sensitive fiber-optic SPR sensor with surface coated TiO₂/MWCNT composite film for hydrogen sulfide gas detection