A resonance light scattering method for determination of DNA using Ru(bpy)2PIP(V)2+

Detection of DNA hybridization by various spectroscopic methods using the copper tetraphenylporphyrin complex as a probe

“…Tetraphenyl-metalloporphyrins play an important role in natural biology with the coordination effect of polydentate ligand and its big ring structure characteristics, such as cutting DNA, improving the function of nucleic acid enzymatic activity, inhibiting the HIV and influenza virus and so on [13,14]. Recently, the interactions between DNA and tetraphenylmetalloporphyrins have attracted immense interest.…”

Synthesis of polycation with gemini structure and detection of DNA by resonance light scattering

“…As a new spectral analysis technique, RLS, which is noted for its high sensitivity, convenience, and high-through, has found wide applications in the detection of biomolecules, such as DNA [17,18], proteins [19][20][21], and so on. For example, RLS technique has been successfully applied to determine DNA in real and artificial samples with various light scattering probes, such as organic dyes [22,23], cationic porphyrins [24], cationic pyridine [25], metal ion [26], metal ion complex [27,28], nanoparticles [29][30][31][32], and cationic surfactant [33][34][35]. However, these small molecule light scattering probes have disadvantages of high material cost or cellular toxicity more or less, which would affect their application in life science.…”

A highly sensitive resonance Rayleigh scattering method to discriminate a parallel-stranded G-quadruplex from DNA with other topologies and structures

“…The spectral characteristics and scattering intensity are strongly influenced by the molecular size, shape, conformation, and interfacial properties, which further provide favorable new information for the study of the interaction of biological macromolecules and the molecular recognition. Usually, the RRS method is used to study the interaction of DNA with other substances such as some drugs, 18 macromolecules, 19 dyes, 20 metal complexes, 21 surfactants, 22 nanoparticles, 23 etc. and then the determination of DNA.…”