A response to the letter to the editor on “Management of hepatitis B reactivation in lymphoma patients on rituximab with past hepatitis B exposure: An observational study”

Hepatitis B virus (HBV) is an important public health problem that poses a serious threat to human health. HBV reactivation generally occurs in overt or occult HBV infection patients who suffered DDAs, chemotherapy, or immunosuppressive therapy, especially when some solid tumors and leukemia patients are using hormones such as prednisolone and imatinib. The approximate incidence of HBV reactivation ranged from about 10% to 40%. Scientists often explore the molecular mechanisms from both the virus and the host. But some studies have reported that some drugs (cisplatin, rituximab, imatinib, and glucocorticoid) could induce HBV reactivation directly. However, the specific molecular mechanisms were unclear. With the emergence of new antiviral drugs and molecular targeted drugs, the risk of HBV reactivation will increase significantly. Therefore this review was expected to be used to provide recommendations for future research in HBV reactivation.

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Recent Advances in HBV Reactivation Research

Guo

Wang

Ouyang

et al. 2018

BioMed Research International

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A response to the letter to the editor on “Management of hepatitis B reactivation in lymphoma patients on rituximab with past hepatitis B exposure: An observational study”

Cited by 1 publication

References 8 publications

Recent Advances in HBV Reactivation Research

Recent Advances in HBV Reactivation Research

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