2021
DOI: 10.1038/s41598-021-81694-7
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A retrospective clinical analysis of pediatric paragonimiasis in a Chinese children’s hospital from 2011 to 2019

Abstract: Diagnosis of pediatric paragonimiasis is difficult because of its non-specific clinical manifestations. We retrospectively reviewed the records of pediatric paragonimiasis in Children’s Hospital of Fudan University from January 2011 to May 2019. The confirmed diagnosis of paragonimiasis was based on positive anti-parasite serological tests from the local Center for Disease Control (CDC). A total of 11 patients (mean age: 7.7 ± 3.1, male–female ratio: 7:4) diagnosed as paragonimiasis were included. 81.8% were f… Show more

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Cited by 9 publications
(21 citation statements)
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“…Immunodiagnostic methods, increasingly preferred because of the difficulties in parasitological diagnosis, can yield positive results in a remarkably high proportion of a tested population (e.g. Qian et al, 2019), which might reflect current or past infection or be due to cross-reactions with other parasites, or to use of inappropriate cut-off values.…”
Section: Is the Prevalence Of Paragonimiasis Decreasing?mentioning
confidence: 99%
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“…Immunodiagnostic methods, increasingly preferred because of the difficulties in parasitological diagnosis, can yield positive results in a remarkably high proportion of a tested population (e.g. Qian et al, 2019), which might reflect current or past infection or be due to cross-reactions with other parasites, or to use of inappropriate cut-off values.…”
Section: Is the Prevalence Of Paragonimiasis Decreasing?mentioning
confidence: 99%
“…Prevalence in China has dropped considerably. Qian et al (2019) have cited results from two national surveys 10 years apart. The first of these (2001)(2002)(2003)(2004)) used serological methods and showed an overall prevalence of 1.7%.…”
Section: Is the Prevalence Of Paragonimiasis Decreasing?mentioning
confidence: 99%
See 1 more Smart Citation
“…P . skrjabini does not mature into an adult in the human body, but the juvenile can migrate to the CNS and cause CP [ 9 , 22 , 23 ]. Whether specific antibodies against P .…”
Section: Discussionmentioning
confidence: 99%
“…Following approaches may provide diagnostic clues; i) history of freshwater crustacean consumption, ii) clinical manifestations, iii) imaging features, iv) laboratory results, and v) serological tests. However, clinical diagnosis is often challenging as non-specific symptoms and signs, and medical information obtained from patients are generally of minimal diagnostic value [ 8 , 9 ]. More than half of paragonimiasis patients did not recall eating freshwater crustaceans, when they are diagnosed years after the onset of clinical symptoms [ 5 ].…”
Section: Introductionmentioning
confidence: 99%