A retrospective cohort study of Acticoat™ versus Silvazine™ in a paediatric population

Silver-Impregnated Dressings for Sternotomy Incisions to Prevent Surgical Site Infections in Children

“…12,13,18,19 Silver-containing dressings have been marketed as bactericidal against a large number of gram-positive and gram-negative organisms for infants and children. 13 The results in the reduction of wound infections are mixed. 19 Huckfeldt et al 10 found that use of silver nylon dressings was statistically related to lower mediastinitis rates in adults.…”

“…The silver material was a conformable, nanocrystalline silver-coated, antimicrobial barrier dressing that allows the passage of exudate and can be affixed for up to 3 days. 12,13 Although Acticoat and Acticoat Flex 3 have different substrates, both contain nanocrystalline silver and provide an equivalent antimicrobial barrier with proven efficacy against highly antibiotic-resistant organisms, a broad spectrum of gram-positive and gram-negative bacteria, and fungal wound pathogens. 14 The chief difference between Acticoat and Acticoat Flex 3 is that the latter is more flexible and therefore more comfortable for patients.…”

Inpatient silver sulphadiazine versus outpatient nanocrystalline silver models of care for pediatric scald burns: A value analysis

“…However, there are few publications outlining the treatment costs or the cost effectiveness of these new advances (1,6,8,9,10). Although achieving optimal closure of burn wounds is of primary importance, the need to find and provide models of care that allow fiscal sustainability are also critical (11)(12)(13). To perform an economic evaluation in a limited field such as burns, the resources spent for effective treatment need to be quantified (8,16,18).…”

“…To perform an economic evaluation in a limited field such as burns, the resources spent for effective treatment need to be quantified (8,16,18). In pediatric burn care, the major cost in the acute setting is associated with hospital stay, multiple burn dressing or operative procedures, and the use of skin substitutes (11,12,14). Additional resources may also be incurred during the rehabilitation period or for operative interventions related to scar pathology, but these were beyond the scope of the present study.…”

Application of the Nanocrystalline Silver in Treatment of Burn Wounds in Children

“…The antibacterial effect can be achieved two hours after application and its maximum activity lasts approximately six hours. The majority of the comparative clinical studies, utilizing biological and non-biological dressings, involves silver sulphadiazine, which shows that it is used as a standard agent for treatment in most burn centres (Huang et al, 2007;Cuttle et al, 2007). Creams and solutions containing silver have been used as main agents in burn wound treatment for a long time.…”