Application of the Nanocrystalline Silver in Treatment of Burn Wounds in Children

Argirova, Maya; Hadjiiski, O.

doi:10.5772/24646

Cited by 3 publications

(2 citation statements)

References 30 publications

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“…Currently, nanosilver containing wound dressings with antibacterial properties are used in treatment of burns [7, 12, 13]. These nanosilver dressings have superior features compared to the silver sulfadiazine (SSD) dressings in terms of antibacterial properties, wound healing, shortened time of wound clearing and epithelization, and painless dressing change [7].…”

Section: Discussionmentioning

confidence: 99%

“…These nanosilver dressings have superior features compared to the silver sulfadiazine (SSD) dressings in terms of antibacterial properties, wound healing, shortened time of wound clearing and epithelization, and painless dressing change [7]. These studies noted that nanosilver-containing wound dressings are used safely and highly efficiently for burn patients and they do not show any toxicological side effects.…”

Section: Discussionmentioning

confidence: 99%

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Biocompatibility of nanosilver-coated orthodontic brackets: an in vivo study

2016

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BackgroundNanosilver particles of which antibacterial and antifungal properties have been shown in various in vitro and in vivo studies are used in many medical and dental fields for the prevention of infection. In this study, it is intended to evaluate the biocompatibility of nanosilver-coated brackets.MethodsNanosilver coating process was applied to the standard orthodontic brackets by a physical vapor deposition system. Brackets were coated with nanosilver particles of 1 μ thickness. A total of 12 Wistar Albino rats were included in the study (six) and control (six) groups. For the study and control groups, four nanosilver-coated and four standard brackets were aseptically implanted subcutaneously in the dorsal region of each rat. The brackets were removed with the surrounding tissues on days 7, 14, 30, and 60. The specimens were evaluated for inflammatory response.ResultsNo significant difference was found in terms of tissue reaction between the study and control groups. On day 7, randomly distributed brown-black granules were seen in the granulation tissue adjacent to the bracket in the study group. These foreign particles continued along the bracket cavity in a few samples, but the inflammatory response was insignificant between the groups. Mast cell count was found to be significantly smaller only on day 7 in the study group than in the control group.ConclusionsNanosilver-coated orthodontic brackets were found to be similar with the standard type concerning inflammation. Further researches are needed with regard to the assessment of the brown-black granules, especially on the deposition of the vessel walls.

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