Nanosilver coated orthodontic brackets:<i>in vivo</i>antibacterial properties and ion release

Metin-Gürsoy, Gamze; Taner, Levent; Akca, Gülçin

doi:10.1093/ejo/cjv097

Cited by 70 publications

(73 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other study evaluated, through an in vivo experimental design, the antimicrobial activity on S. mutans bacteria and the ion release capacity of nanosilver-coated orthodontic brackets; these authors concluded that AgNP-coated brackets could significantly help to decrease the presence of spot lesions during fixed orthodontic treatments, even may have a potential solution for systemic compromised patients such as immune deficiency, diabetics, and subacute bacterial endocarditis. [21]. Our results agree with these results indicating that both sizes of AgNP samples have significant ability to inhibit the adherence capacity of S. mutans bacteria on surfaces of elastomeric modules and orthodontic brackets, even for these orthodontic brackets and elastomeric modules crisscrossed (p < 0 05).…”

Section: Discussionsupporting

confidence: 91%

“…Recently, silver nanoparticles (AgNPs) have been shown to be materials with excellent antimicrobial properties in a wide variety of microorganisms [6,[16][17][18][19]. In the orthodontic field, studies have incorporated AgNPs (17 nm) into orthodontic elastomeric modules, orthodontic brackets and wires, and others, against a wide variety of bacterial species concluding that these orthodontic appliances with AgNPs could potentially combat the dental biofilm decreasing the incidence of dental enamel demineralization during and after the orthodontic treatments [20][21][22][23]. However, there is no information that has evaluated the antimicrobial effect and antiadherence activity of AgNPs against S. mutans bacteria on orthodontic bracket surfaces and its relationship with the presence of the elastomeric modules as well as different types of metallic orthodontic wires and the involved factors in the adherence of these bacteria.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Antiadherence and Antimicrobial Properties of Silver Nanoparticles against Streptococcus mutans on Brackets and Wires Used for Orthodontic Treatments

Espinosa-Cristóbal

López-Ruiz

Cabada-Tarín

et al. 2018

Journal of Nanomaterials

View full text Add to dashboard Cite

White spot lesions (WSLs) are very frequent alterations during orthodontic treatments causing demineralization of the dental enamel. Various dental treatments have been developed to prevent WSLs; the prevalence and incidence of these lesions remain significantly high. Although silver nanoparticles (AgNPs) have demonstrated good inhibitory effects against several microorganisms, more studies about antiadherence activity on different orthodontic appliance surfaces are necessary. To determine the inhibitory effect and antiadherence activity of AgNPs on the adhesion of S. mutans on surfaces of brackets and wires for orthodontic therapies, two sizes of AgNPs were prepared and characterized. The evaluation of S. mutans adhesion was performed with microbiological assays on surfaces of brackets and orthodontic modules in triplicate. Topographic characteristics of orthodontic brackets and wires were made by scanning electron and atomic force microscopies. All AgNP samples inhibited S. mutans adhesion; however, the smaller AgNPs had better inhibition than the larger ones. The presence of the module influenced the adhesion of S. mutans but not in the activity of AgNPs. The AgNPs used in this study showed to have good antimicrobial and antiadherence properties against S. mutans bacteria determining its high potential use for the control of WSLs in orthodontic treatments.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Antiadherence and Antimicrobial Properties of Silver Nanoparticles against Streptococcus mutans on Brackets and Wires Used for Orthodontic Treatments

Espinosa-Cristóbal

López-Ruiz

Cabada-Tarín

et al. 2018

Journal of Nanomaterials

View full text Add to dashboard Cite

show abstract

“…As a result of our clinical observations, differences considered to be symptoms of argyria were observed in none of the animals. A previous study showed that nanosilver-coated orthodontic brackets prevent caries formation via its antibacterial properties [16]. The present study suggests, with the support of other previous studies, that nanosilver-coated orthodontic brackets have no disadvantage in terms of biocompatibility, and also it can be useful during fixed orthodontic treatment.…”

Section: Discussionsupporting

confidence: 87%

“…The nanoparticles show efficient antimicrobial properties due to their extremely large surface area, which provides better contact with microorganisms. Researchers reported that orthodontic brackets coated with nanoparticles or combining dental material with nanoparticles show antibacterial and anti-adhesive properties against normal oral pathogenic bacteria [15, 16]. …”

Section: Introductionmentioning

confidence: 99%

Biocompatibility of nanosilver-coated orthodontic brackets: an in vivo study

2016

Self Cite

View full text Add to dashboard Cite

BackgroundNanosilver particles of which antibacterial and antifungal properties have been shown in various in vitro and in vivo studies are used in many medical and dental fields for the prevention of infection. In this study, it is intended to evaluate the biocompatibility of nanosilver-coated brackets.MethodsNanosilver coating process was applied to the standard orthodontic brackets by a physical vapor deposition system. Brackets were coated with nanosilver particles of 1 μ thickness. A total of 12 Wistar Albino rats were included in the study (six) and control (six) groups. For the study and control groups, four nanosilver-coated and four standard brackets were aseptically implanted subcutaneously in the dorsal region of each rat. The brackets were removed with the surrounding tissues on days 7, 14, 30, and 60. The specimens were evaluated for inflammatory response.ResultsNo significant difference was found in terms of tissue reaction between the study and control groups. On day 7, randomly distributed brown-black granules were seen in the granulation tissue adjacent to the bracket in the study group. These foreign particles continued along the bracket cavity in a few samples, but the inflammatory response was insignificant between the groups. Mast cell count was found to be significantly smaller only on day 7 in the study group than in the control group.ConclusionsNanosilver-coated orthodontic brackets were found to be similar with the standard type concerning inflammation. Further researches are needed with regard to the assessment of the brown-black granules, especially on the deposition of the vessel walls.

show abstract

“…These are including certain NPs, such as nanofillers, silver, TiO 2 , SiO 2 , hydroxyapatite, fluorapatite, fluorohydroxyapatite, into orthodontic bonding materials or acrylic resins and coating surfaces of brackets and bands. Information of using nanotechnology is lacking; thus, further investigation to assess possible toxicity related to the NP sizes is required [106][107][108].…”

Section: Increasing Tooth Resistancementioning

confidence: 99%

The Relationship between Orthodontic Treatment and Dental Caries

Metin-Gürsoy¹,

Uzuner²

2018

Dental Caries - Diagnosis, Prevention and Management

Self Cite

View full text Add to dashboard Cite

Orthodontic treatment is the main treatment procedure to achieve a well-aligned dental arch and an esthetic smile. For this purpose, various types of removable or fixed orthodontic appliances are designed. However, each has their specific disadvantages. The most important one is that orthodontic appliances especially the brackets and the ligation mode create new retention areas in addition to blocking plaque-removing shear forces arising from fluid flow and masticatory loads with a resultant undesired effect of accumulation of dental plaque. Increased amount of dental plaque containing cariogenic bacteria is the main etiologic factor in decalcification of enamel during orthodontic treatment. This demineralization of the tooth surfaces results in appearance of white spots or even caries. However, in the literature, there are conflicting results in the relationship between orthodontic treatment and development of dental caries. Many preventive methods such as topical fluoride application, using bonding materials releasing fluoride, using mouth rinse with sodium fluoride, applying chlorhexidine, and so on were defined. The general comment of the authors is that supplying an adequate oral hygiene has the main role in prevention of demineralization-caries during orthodontic treatment. In the light of the previous studies' results, it can be concluded that professional application like a varnish can be provided for patients who have high caries incidence.

show abstract

Nanosilver coated orthodontic brackets:in vivoantibacterial properties and ion release

Abstract: It is suggested that nanosilver coated orthodontic brackets, as an antibacterial agent without patient compliance, could be helpful for the prevention of white spot lesions during fixed orthodontic treatment.

Cited by 70 publications

References 46 publications

Antiadherence and Antimicrobial Properties of Silver Nanoparticles against Streptococcus mutans on Brackets and Wires Used for Orthodontic Treatments

Antiadherence and Antimicrobial Properties of Silver Nanoparticles against Streptococcus mutans on Brackets and Wires Used for Orthodontic Treatments

Biocompatibility of nanosilver-coated orthodontic brackets: an in vivo study

The Relationship between Orthodontic Treatment and Dental Caries

Contact Info

Product

Resources

About