Background: Inequities in stillbirth rate according to ethnicity persist
in high income nations. Objectives: To investigate whether causes of
stillbirth differ by ethnicity in high-income nations. Search strategy:
Medline, Embase, Scopus, CINAHL, Cochrane Library, and Global Health
databases since their inception to 1 February 2021. Selection criteria:
Cohort, cross-sectional, and retrospective studies investigating the
causes of stillbirth in various ethnic groups. Data collection and
analysis: Systems of classification and causes of stillbirth were
aligned to the International Classification of Disease 10 for Perinatal
Mortality (ICD10-PM) and pooled estimates were derived by meta-analysis.
Main results: Fifteen reports from 3 countries (72,555 stillbirths) were
included. Seven ethnic groups – “Caucasian” (n = 11 studies, n =
37,578 stillbirths), “African” (n = 11 studies, n = 17,883
stillbirths), “Hispanic” (n = 7 studies, n = 12,810 stillbirths),
“Indigenous Australian” (n = 4 studies, n = 1,117 stillbirths),
“Asian” (n = 2 studies, n = 15 stillbirths), “South Asian” (n = 2
studies, n = 55 stillbirths), and “American Indian” (n = 1 study, n =
27 stillbirths) – were identified. There was an overall paucity of
recent, high-quality data for many ethnicities. For those with the
greatest amount of data – Caucasian, African, and Hispanic – no major
differences in the causes of stillbirth were identified. Conclusion:
There is a paucity of high-quality information on causes of stillbirth
for many ethnicities. Improving investigation and standardising
classification of stillbirths is needed to assess whether causes of
stillbirth differ across more diverse ethnic groups.