A retrospective study of hydatid cysts in patients undergoing liver and lung surgery in Tehran, Iran

Abstract

Hydatid cyst, caused by larval stages of Echinococcus granulosus, is a zoonotic parasitic disease with public health importance. The disease is cosmopolitan and endemic in Iran. We conducted a retrospective study of the records of Milad Hospital, Tehran, Iran to establish the proportion of lung and liver surgical procedures that were performed for removal of hydatid cyst and to investigate the demography of the population undergoing lung and liver hydatid cyst surgery in this hospital. A retrospective cross-sectional study was conducted of records of 682 patients who underwent liver (n = 404) or lung (n = 278) surgery from April 2009 to March 2013. In 404 liver surgeries, 111 (27.5%) diagnoses of hydatid cyst were verified. Liver hydatid infection demonstrated a significant age-related difference (p < 0.05). Cysts were found in 64 of 217 females (29.5%) and 47 of 187 males (25.1%). While in both sexes, more cysts were found in liver, the liver/lung ratio in females was significantly higher than in males (p < 0.001). Hydatid cyst was verified in 59 (21.2%) of 278 lung surgeries: 27 of 105 females (25.7%) and 32 of 173 males (18.5%). There was a significant relationship between sex and organ site (p < 0.001) with the proportion of hydatid cysts in males occurring in lung higher than seen in females. In the five investigated years, approximately 25% of liver and lung surgeries conducted at Milad Hospital were related to hydatidosis. Increasing public awareness of principles of avoiding infection could reduce the risk of nearly a quarter of liver and lung surgeries and costs associated with the treatment of hydatid cysts.

Laparoscopic Treatment of Hydatid Cyst of Liver: Outcome at Tertiary Care Hospital

“…However inconsistently Rooh-ul-Muqim KK et al [16] reported that females were commonest 62.79% and males were 37.20%. Others also observed female predominance [16,17]. In this study mean size of the cyst was 8.6 cm.…”

Detection and genetic characterization of Echinococcus granulosus mitochondrial DNA in serum and formalin-fixed paraffin embedded cyst tissue samples of cystic echinococcosis patients

“…This zoonotic disease has worldwide distribution and is endemic in many countries, including Iran [5]. Human CE is reported in all parts of Iran and is the basis for nearly 1% of all surgical procedures [6] and 25% of liver and lung surgeries [7]. The condition becomes symptomatic as the cyst grows, with highly variable clinical manifestations depending on location and size [8].…”

Hydatid Disease in the Western Region of Saudi Arabia, A University Medical Center Experience

“…The mean age of patients included in our study was 40 ± 17 years, and the peak age group was 25-50 years. While some reports from other countries like Turkey, Iran and India showed relatively similar peak age, the incidence was higher in females than males [6,[13][14][15][16]. Rao et al, have postulated that women are involved more than men in farming and herding livestock in their country; therefore women have more risk to get the disease [16].…”