A retrospective study of the prevalence and incidence of recurrent aphthous ulcers in a professional population, 1958–1971

Miller, Michael; Ship, Irwin I.; Ram, Carol

doi:10.1016/0030-4220(77)90105-0

Cited by 75 publications

(52 citation statements)

References 6 publications

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“…It is one of the most painful oral inflammatory ulcerative conditions which cause pain during eating, swallowing and speaking (Miller and Ship, 1977;Sircus et al, 1967). Recurrent aphthous stomatitis is the most common oral condition diagnosed by dentists and physicians (Rogers, III, 1977;Woo and Sonis, 1996).…”

Section: Introductionmentioning

confidence: 98%

The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis

Moghadamnia

Mina

Khanian

2008

Phytotherapy Research

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This study evaluated the efficacy of licorice bioadhesive hydrogel patches to control the pain and reduce the healing time of recurrent aphthous ulcer.This study was carried out in three episodes of ulcers: in the first episode of ulcer, all 15 patients were asked to record their baseline individual pain level by a visual analog scale. In the second and third episodes, comparative and consecutive subjective and objective evaluations of the bioadhesive were done. The effects of the following variables were investigated: (1) VAS pain score for 5 consecutive days, (2) profile of aphthous ulcers on days 3 and 5, (3) time to complete relief of pain and healing of the ulcers, (4) diameter of the lesions and necrotic zone.A significant reduction in VAS was recorded following application of the licorice patches on days 2, 3, 4 and 5 compared with the no-treatment group (p < 0.001). Licorice patches caused a significant reduction in the diameter of the inflammatory halo and necrotic center compared with the placebo group (p = 0.03).According to the results of this study, licorice bioadhesive can be effective in the reduction of pain and of the inflammatory halo and necrotic center of aphthous ulcers.

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Section: Introductionmentioning

confidence: 98%

The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis

Moghadamnia

Mina

Khanian

2008

Phytotherapy Research

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“…Psychological illness has been proposed to initiate some episodes of RAS (Ship et al, 1961b;Miller et al, 1977a), and there are sparse data to suggest that some patients may benefit from antidepressant therapy (Yaacob and Hamid, 1985). Nevertheless, no significant objective neurosis has been observed in two further studies (Pedersen, 1989;Buajeeb et al, 1990).…”

Section: Clinical Featuresmentioning

confidence: 99%

Recurrent Aphthous Stomatitis

Porter

Scully

Pedersen

1998

Critical Reviews in Oral Biology & Medicine

252

143

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“…Ayrıca orta gelirli ve düşük eğitim düzeyi olanlarda lezyon sayısının daha fazla; yüksek eğitim ve yüksek gelir düzeyi olanlarda daha az olduğu gözlendi. Literatürde RAS'ın yüksek sosyoekonomik düzeydeki bireylerde daha sık görüldüğü bildirilmiş, bu durum bu popülasyonda karşılaşılan stres faktörleri ile ilişkilendirilmiştir [15][16][17] . Bölgemizin sosyoekonomik özellikleri göz önünde bulundurulduğunda bulgularımızdaki bu farklılık şaşırtıcı değildir.…”

Section: Discussionunclassified

Sociodemographic and clinical characteristics of patients with recurrent aphthous stomatitis

Bahalı¹,

Köktürk²,

Güvenç³

2014

TURKDERM

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Background and Design:The purpose of this study was to obtain data that may provide an insight into the etiopathogenesis of recurrent aphtous stomatitis (RAS) by the way of analysing the sociodemographic and clinical characteristics of patients who had been diagnosed with RAS. Materials and Metods: The patients, who were diagnosed with RAS in the dermatology outpatient clinic, between May 2007 and May 2010, were evaluated retrospectively. The data including sociodemografic and clinical characteristics, and treatment options were recorded. Results: A hundred patients (68 women, 32 men) were included in this study. The average age was 40±13.6 years. RAS was more common in patients with middle-income and low education. The most common type of RAS was minor aphtous ulcers (88%). The lesions were most frequently seen on the lateral side of the tongue (34%) and cheek (34%). Sixty percent of patients had a positive family history. Some factors such as biting (12%), tooth brushing (18%), dental disease presence (82%), food (39%), menstruation (10.3%), stress (76%), iron deficiency (16.7%), vitamin B12 deficiency (22.4%), low serum ferritin levels (18%), and seasonal variability (32%) showed positive correlation with RAS. A negative correlation was found between RAS and smoking. Forty-nine percent of patients had used alternative therapies in addition to drug therapy. The most frequently used alternative method was consumption of sumac (26.5%). Conlucions: In contrast to the literature, our study found that RAS is started in the third decade of life and, approximately 50% of patients prefered alternative treatment methods, particularly sumac. Nowadays, discussions about the etiopathogenesis of RAS continue. In this study, we found that different sociodemographic and clinical factors may be associated with the etiopathogenesis of the disease. Our study will be followed by further studies using prospective design to identify the the etiopathogenesis of RAS. (Turkderm 2014; 48: 242-8)

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A retrospective study of the prevalence and incidence of recurrent aphthous ulcers in a professional population, 1958–1971

Cited by 75 publications

References 6 publications

The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis

The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis

Recurrent Aphthous Stomatitis

Sociodemographic and clinical characteristics of patients with recurrent aphthous stomatitis

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