A Review of Binocular Treatment for Amblyopia

Lamprogiannis, Lampros; MacKeith, Daisy; Vivian, Anthony J.

doi:10.17925/eor.2020.14.1.34

Cited by 7 publications

(8 citation statements)

References 28 publications

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“…This is consistent with the approach first recommended by Darwin, 2 Javal 13 Worth 14 and Maddox 15 and detailed in a number of recent reviews. [16][17][18][19] The unphysiological nature of the opaque patching approach Primates, because of their front facing eyes, which affords significant overlap between the left and right visual fields, are endowed with binocular vision. The foundations for binocularity are well established (though not stereopsis) at birth and is supported by a set of elaborate excitatory and inhibitory circuits in the early visual cortex.…”

Section: Why Patching? Historical Perspectivementioning

confidence: 99%

Reasons why we might want to question the use of patching to treat amblyopia as well as the reliance on visual acuity as the primary outcome measure

Hess

2022

BMJ Open Ophth

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Section: Why Patching? Historical Perspectivementioning

confidence: 99%

Reasons why we might want to question the use of patching to treat amblyopia as well as the reliance on visual acuity as the primary outcome measure

Hess

2022

BMJ Open Ophth

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“…It might be unilateral or bilateral 7 . optimal management of amblyopia is one of the primary challenges in pediatric ophthalmology research 8 .…”

Section: Resultsmentioning

confidence: 99%

Evaluation of interactive binocular treatment in amblyopia

El-shayeb

El-Deen

Kasem

et al. 2022

Egyptian Journal of Ophthalmology, (Mansoura Ophthalmic Center)

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Purpose: This study was to evaluate effectiveness of I-BiT system for treatment of amblyopia in comparison with standard patching of dominant eye.Methods: This was a prospective randomized comparative study conducted on cooperative amblyopic patients up to 20 years attending outpatient clinic of Mansoura University, Ophthalmic Center. All cases were exposed to full history taking, ophthalmic history, ocular examination which included assessment of visual acuity, slit lamp biomicroscopy, in addition to, Worth 4 Dot Test and Lang test.Results: there was a statistically significant improvement in the (BCVA) (p <0.001) of both groups after 6 months of treatment. There was a statistically significant improvement of Worth 4 dot test results with increased fusion in the cases of both groups. There was a statistically significant improvement of Lang test and achieving positive results in the cases of group 1(29.4% of cases) and group 2 (10.5% of cases) at 6 months of treatment as compared with the pretreatment data.Conclusion: I-BiT system can give equal results to patching of sound eye in treating cases of moderate amblyopia but in a new, simple and joyful way.

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“…Rapid advancements in technology have generated considerable interest in the use of dichoptic binocular movies and games as a potential treatment for amblyopia 37,46,75 . Poor adherence is a known risk in home‐based studies, 76 and compliance with many earlier binocular treatments was a concern, due to a lack of interest in the dichoptic games, 77–79 with one investigation demonstrating that children had significantly lower gain in VA if their compliance was <50% 80 . However, more recent randomised trials have reported better compliance, and also found a significant improvement in VA in the binocular training group compared with patching cohorts 47,78,81 …”

Section: Discussionmentioning

confidence: 99%

Amblyopia—A novel virtual round table to explore the caregiver perspective

Nowik

Perna

Dahlmann‐Noor

et al. 2023

Ophthalmic Physiologic Optic

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PurposeA survey aimed to capture the caregiver's perspective on the impact of amblyopia and its treatment on the child and family, as well as caregivers' views on the design and feasibility of clinical trials investigating dichoptic binocular therapies for amblyopia.MethodsParents of amblyopic children, patient advocates and healthcare professionals took part in a moderated, structured discussion on a novel virtual advisory‐board platform.ResultsSeven parents of children with amblyopia, two patient organisation representatives, one ophthalmologist and one optometrist participated in the survey. A total of 645 posts were entered on the platform over a 14‐day period in September 2021. There was widespread agreement that the management of amblyopia poses more of a burden on the child and family than the condition itself, with treatment burden accentuated when treatment is unsuccessful. Parents expressed uncertainty and frustration in relation to the duration of patching, success of patching and alternative treatment options, and felt there was inadequate readily available, easy‐to‐understand information on the condition. Parents reported that a new treatment for amblyopia, such as dichoptic binocular therapy using video games, should be safe, non‐invasive and engaging compared with an eye patch. Treating at home, potentially for a shorter treatment duration, and with an entertaining game were the main reasons parents would join a clinical study with this type of novel therapy. However, due to a limited critical period treatment window, parents would feel more comfortable joining a clinical trial if traditional therapies were offered in conjunction with those under investigation.ConclusionPatient perspectives and the role of caregivers in the acceptance of any interventional treatments are increasingly recognised. Understanding how amblyopia and its treatment impacts a child and family should be an important premise to guide therapy and evaluate treatment value, both in clinical trials and in routine medical practice.

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A Review of Binocular Treatment for Amblyopia

Cited by 7 publications

References 28 publications

Reasons why we might want to question the use of patching to treat amblyopia as well as the reliance on visual acuity as the primary outcome measure

Reasons why we might want to question the use of patching to treat amblyopia as well as the reliance on visual acuity as the primary outcome measure

Evaluation of interactive binocular treatment in amblyopia

Amblyopia—A novel virtual round table to explore the caregiver perspective

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