A review of current trends in HIV epidemiology, surveillance, and control in Nigeria

Bassey, Archibong Edem; Miteu, Goshen David

doi:10.1097/ms9.0000000000000604

Cited by 3 publications

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The top three are Ghana (8.43%), Cape Verde (8.29%), and Burkina Faso (7.60%) . There are various limitations, including insufficient laboratories and infrastructure, supposed lack of skilled human resources, ethical issues, and potentially overwhelming growth in human population size Aborode et al, 2021;Bassey and Miteu, 2023). However, unique surveillance challenges exist for HIV-2 patients due to its lower global profile compared to that of HIV-1 patients.…”

Section: Surveillance Challengesmentioning

confidence: 99%

HIV-2 Incidence Decline in West Africa - A Perspective on the Need for Vigilance

Lauya,

Okeke,

Cosmas

et al. 2024

View full text Add to dashboard Cite

In the context of the epidemiology of HIV/AIDS in West Africa, the declining incidence of HIV-2 elicits mixed feelings of victory and doubt. Previously, we published a systematic literature review which identified factors contributing to this declining trend but also raised concerns about its sustainability. The aim of this article is to caution against interpreting this trend as a triumph against HIV/AIDS in the region. This caution is deserved due to serious challenges in West Africa that require liberal attention. These include; inadequate diagnostic methods and algorithms for monitoring HIV-2, the possibility of dangerous genetic mutations and resurgence of super-strains, cross-reactivity of HIV types that interfere with accurate reporting of HIV-2 cases, and suboptimal/neglected treatment and care (S/NTC) for HIV-2 individuals. Additionally, gaps in surveillance infrastructure, health inequality in classifying HIV burdens based on HIV type, and deprived HIV-2 research and policy enforcement could create obscurity in HIV-2 data. Considering the existing circumstances, this article highlights the importance of vigilance, re-evaluation of assumptions, and advocacy for unified efforts to address the multidimensional problems associated with HIV-2 to guarantee the sustained integrity of public health.

show abstract

Section: Surveillance Challengesmentioning

confidence: 99%

HIV-2 Incidence Decline in West Africa - A Perspective on the Need for Vigilance

Lauya,

Okeke,

Cosmas

et al. 2024

View full text Add to dashboard Cite

show abstract

Antiretroviral therapy retention, adherence, and clinical outcomes among postpartum women with HIV in Nigeria

Young,

Chang,

Sagay

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

While research involving pregnant women with HIV has largely focused on the antepartum and intrapartum periods, few studies in Nigeria have examined the clinical outcomes of these women postpartum. This study aimed to evaluate antiretroviral therapy retention, adherence, and viral suppression among postpartum women in Nigeria. This retrospective clinical data analysis included women with a delivery record at the antenatal HIV clinic at Jos University Teaching Hospital between 2013 and 2017. Descriptive statistics quantified proportions retained, adherent (≥95% medication possession ratio), and virally suppressed up to 24 months postpartum. Among 1535 included women, 1497 met the triple antiretroviral therapy eligibility criteria. At 24 months, 1342 (89.6%) women remained in care, 51 (3.4%) reported transferring, and 104 (7.0%) were lost to follow-up. The proportion of patients with ≥95% medication possession ratio decreased from 79.0% to 69.1% over the 24 months. Viral suppression among those with results was 88.7% at 24 months, but <62% of those retained had viral load results at each time point. In multiple logistic regression, predictors of loss to follow-up included having a more recent HIV diagnosis, higher gravidity, fewer antenatal care visits, and a non-hospital delivery. Predictors of viral non-suppression included poorer adherence, unsuppressed/missing baseline viral load, lower baseline CD4+ T-cell count, and higher gravidity. Loss to follow-up rates were lower and antiretroviral therapy adherence rates similar among postpartum women at our study hospital compared with other sub-Saharan countries. Longer follow-up time and inclusion of multiple facilities for a nationally representative sample would be beneficial in future studies.

show abstract

A mathematical and sensitivity analysis of an HIV/AIDS infection model

Ahmed,

Tariboon,

Muhammad

et al. 2024

International Journal of Mathematics and Computer in Engineering

View full text Add to dashboard Cite

Over the past decade, Human Immunodeficiency Virus infection and Acquired Immunodeficiency Syndrome (HIV/AIDS) have become deadly infectious diseases, particularly in developing countries. This challenge has led to the development of some important HIV/AIDS treatment strategies, such as antiretroviral therapy (ART), among many others. This study presents a mathematical model to investigate the dynamics of HIV/AIDS transmission. Employing mathematical analysis, non-negativity, boundedness, the basic reproduction number ℛ 0, and the stability of both the disease-free and endemic equilibrium of the proposed model were derived. Normalized forward sensitivity techniques are used to determine the significance and importance of sensitive parameters associated with ℛ 0. To gain insights into the dynamical behavior of each compartment, an effective numerical scheme was utilized, and the results obtained suggest that there is a need, even if individuals are infected with the virus, to use non-pharmaceutical interventions as control strategies.

show abstract

A review of current trends in HIV epidemiology, surveillance, and control in Nigeria

Cited by 3 publications

References 23 publications

HIV-2 Incidence Decline in West Africa - A Perspective on the Need for Vigilance

HIV-2 Incidence Decline in West Africa - A Perspective on the Need for Vigilance

Antiretroviral therapy retention, adherence, and clinical outcomes among postpartum women with HIV in Nigeria

A mathematical and sensitivity analysis of an HIV/AIDS infection model

Contact Info

Product

Resources

About