A review of methanol poisoning: a crisis beyond ocular toxicology

Abstract

At first blush, methanol poisoning may be seen as an arcane problem generally associated with rapid ocular neuropathy. The emerging clinical reality is that methanol poisoning around the globe has claimed increasingly large numbers of deaths largely due to the press of poverty and the delay in suspecting and diagnosing methanol toxicity. With the onset of the COVID-19 pandemic, false beliefs about methanol's preventive potential vs viral infection of have arisen. In March of this year, more than 300 Iranians died and 1000 became ill after consuming methanol in the hope that it would protect them against the novel coronavirus. We review the context and magnitude of methanol toxicity, pathophysiology, principal medical issues, and human variability in metabolism. While toxicologists and clinicians may need to be especially attentive to this problem, it is becoming clear that the social and economic underpinnings of the methanol poisoning crisis must be actively and urgently explored and managed as vigorously as its toxicologic and pathophysiologic components. ARTICLE HISTORY

COVID-19 Among People Living with HIV: A Systematic Review

“…Following the Systematic Reviews and Meta-Analyses (PRISMA) checklist (see the Supplementary File S1) and the Peer Review of Electronic Search Strategies [9] guideline [10,11], we searched PubMed, Scopus, Web of Science, Embase, preprint databases (medRxiv, bioRxiv, Preprints), the references of publications found, and the "cited by" feature of Google Scholar from December 1, 2019, to June 1, 2020, for studies published in English. Search terms were combined using appropriate Boolean operators and included subject heading terms/keywords relevant to COVID-19 (e.g., SARS-CoV-2 OR Coronavirus Disease 2019 OR COVID-19 OR severe acute respiratory syndrome coronavirus 2 OR coronavirus infection) and HIV (e.g., HIV OR human immunodeficiency virus OR AIDS OR Acquired Immunodeficiency Syndrome).…”

Characterization of a Spirit Beverage Produced with Strawberry Tree (Arbutus unedo L.) Fruit and Aged with Oak Wood at Laboratorial Scale

“…Methanol is an undesirable compound in all spirits, given its toxicity [39], and its restrictive control is mandatory, but it does not directly affect the flavour of the distillate. All the values found in this work were lower than the legal limit.…”

COVID-19 among people living with HIV: A systematic review

“…Following the Systematic Reviews and Meta-Analyses (PRISMA) checklist (see supplementary file S1) and the Peer Review of Electronic Search Strategies (9) guideline (10, 11), we searched PubMed, Scopus, Web of Science, Embase, preprint databases (medRxiv, bioRxiv, Preprints), the references of publications found, and the “cited by” feature of Google Scholar from December 1, 2019 to June 1, 2020 for studies published in English. Search terms were combined using appropriate Boolean operators and included subject heading terms/keywords relevant to COVID-19 (e.g., SARS-CoV-2 OR Coronavirus Disease 2019 OR COVID-19 OR severe acute respiratory syndrome coronavirus 2 OR coronavirus infection) and HIV (e.g., HIV OR human immunodeficiency virus OR AIDS OR Acquired Immunodeficiency Syndrome).…”