Humans increasingly experience climate change through its influence on water availability, quality, and timing. Droughts threaten the availability of water for drinking, energy, irrigation, and inland navigation, which in turn threaten the food supply, commerce, and industry. Hurricanes and extreme precipitation events threaten homes, infrastructure, fisheries, and local economies. Rising seas compound these threats while encroaching on freshwater aquifers and rendering many long-inhabited areas unlivable. Increased ocean temperatures and acidity threaten seafood availability (the source of 70% of human protein intake), biodiversity, and ecosystem services. Increased humidity magnifies threats from insects and other vectors of disease. This special issue of Climatic Change investigates what, if anything, humans are doing to adapt to a world that at various times and places is both wetter and drier, more hazardous, and less inhabitable. Adaptation is the reduction of the vulnerability of human and natural systems to climate change. It involves changes in business-as-usual practices and policies so that we better protect ourselves. Are humans actually taking such precautions? Of the many water impacts of climate change, those that involve water excess are the focus here: storms, flooding,