A review of natural remedies commonly used by Ethiopian immigrants in the USA

Hailemeskel, Bisrat; Fullas, Fekadu; Habte, Anteneh; Al-matari, Ranyia Ali; Brewer, D.T.

doi:10.4172/2529-797x.1000024

Cited by 3 publications

(6 citation statements)

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“…Local communities use M. stenopetala for unspecified stomach problems such as abdominal cramps, diarrhea, and diarrhea-associated conditions [ 15 , 16 ]. In southern Ethiopia, M. stenopetala is also used to treat indigestion and a form of diarrhea like dysentery [ 13 , 17 ]. From the same family, Moringa oleifera demonstrated significant protection against experimentally induced diarrhea [ 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract of Moringa stenopetala Baker f. in Mice

Woldeyohannes

Eshete

Abiye

et al. 2022

Biochemistry Research International

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Introduction. In Ethiopia, different medicinal plants have been claimed and used to treat diarrheal diseases. However, these claimed effects for most medicinal plants have not been scientifically verified. One of such plants in Ethiopian folkloric medicine is Moringa stenopetala, which is usually consumed as a vegetable in southern Ethiopia. Thus, this study aimed to evaluate the antidiarrheal and antisecretory effects of 80% methanolic leaf extract of Moringa stenopetala in different mice models. Method. Using Swiss albino mice, castor oil-induced diarrhea, charcoal meal-based gastrointestinal motility, and castor oil-induced secretion models were employed to assess antidiarrheal activity. In all of the test models, animals were randomly assigned into five groups consisting of six animals in each group. Group I received 0.5 ml of the vehicle (2% tween-80), while group II was treated with standard drug (3 mg/kg loperamide) in the respective models, whereas groups III to V received 150, 300, and 450 mg/kg of the methanolic leaf extracts of Moringa stenopetala. Onset, frequency, consistency, and weight of stool (diarrhea) were recorded, and different parameters and percentage proportions were calculated. Data were analyzed using one-way ANOVA followed by Tukey’s test, and p < 0.05 was considered statistically significant at 95% confidence of interval. Result. In the castor oil-induced diarrheal model, the percentage inhibition of diarrhea was 48.5, 58.6, and 60% for the respective doses of 150, 300, and 450 mg/kg of the extract. And, the extract showed a 36.8, 54.4, and 55.9% reduction of peristalsis in charcoal meal-based gastrointestinal motility test compared to the negative control group. Moreover, in the antisecretory assay, the 150, 300, and 450 mg/kg doses of MEMS inhibited fluid contents of the stool by 11.5, 54.54, and 61.82%, respectively, relative to the vehicle-treated group. Conclusion. The findings revealed that the 80% methanolic leaf extract of Moringa stenopetala extract has shown antidiarrheal activity.

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Section: Introductionmentioning

confidence: 99%

Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract of Moringa stenopetala Baker f. in Mice

Woldeyohannes

Eshete

Abiye

et al. 2022

Biochemistry Research International

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“…Ocimum lamiifolium has a long history of use for the treatment of various diseases. In many areas, the leaves of the plant are harvested and manually hand rubbed to extract the juice, which is then used as a rinse for the eyes to treat eye infections and inhaled to alleviate symptoms of the common cold and cough [1,18,19]. According to these authors, damakase juice has been used to treat various ailments such as cough, influenza, common cold, headache, eye infection, hematuria, and mich (fever with headache), by either drinking the juice with coffee or tea, or by boiling its leaves in an iron pan and inhaling the vapor.…”

Section: Methods Of Traditional Damakase Preparation and Usesmentioning

confidence: 99%

“…In certain areas, mothers or daughters apply the extracted juice. Additionally, crushed damakase leaves have been directly inserted into the nose and massaged on the face to treat influenza, cold, and fever with headaches [1,2,18,19]. According to Gedif and Hahn's [20] study report, fresh leaf water extract is drunk to treat diarrhea, amoeba (diarrhea with blood), and cough/cold.…”

Section: Methods Of Traditional Damakase Preparation and Usesmentioning

confidence: 99%

“…has been one of the most important and widely used raw forms for treating different diseases in traditional medicine by Ethiopians for a long period [1,15]. It is commonly used to treat gastrointestinal disorders (diarrhea, stomach cramps, and diarrhea), inflammation, fever, malaria, respiratory problems (coughs, colds, and bronchitis), skin infections (wounds, burns, and fungal infections), and pain and inflammation (headaches, burns, and joint pain) [17,18]. It is also widely used in societies to treat inflammatory and infectious diseases known locally as 'mitch,' which are characterized by headaches, fever, inflammation, joint pain, back pain, chills, sweets, loss of appetite, and, in severe cases, diarrhea.…”

Section: Traditional Medicinal Uses Of Damakasementioning

confidence: 99%

“…Moreover, the broad-spectrum bactericidal and fungicidal potential of the oil, as well as its free radical scavenging activity, support its traditionally claimed medicinal value [1]. Damakase is a specialty shop and Internet-ordered item in the United States, and it is not widely used among the population [18].…”

Section: Traditional Medicinal Uses Of Damakasementioning

confidence: 99%

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Damakase (<i>Ocimum lamiifolum</i> Hochest ex Benth): A Medicinal Plant Used in Ethiopian Traditional Medicine: A Critical Review

Megersa

2024

JPS

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Damakase (<i>Ocimum lamiifolum </i>Hochest ex Benth) is a traditional medicinal plant belonging to the Lamiaceae family and a popular home remedy in Ethiopia. It is a well-known and widely used ancient therapeutic herb in various regions of the nation. The utilization of plant leaves for medicinal purposes is primarily due to their rich content of bioactive compounds with therapeutic properties. Consequently, this plant is employed in the management of a condition referred to as 'Mich' in Ethiopia. Additionally, it is frequently used to address diverse health conditions, including gastrointestinal disorders, inflammatory conditions, pyrexia, and respiratory ailments. Moreover, the essential oil derived from Ocimum lamiifolium consists of specific chemical constituents, such as alkaloids, sterols, carbohydrates, glycosides, tannins, flavonoids, bornyl acetate, p-cymene, camphene, α-pinene, and sabinene. Bioactive constituents, such as phenolics, flavonoids, and terpenoids, exhibit antibacterial, antioxidant, and anti-inflammatory properties. Furthermore, the potential applications of damakase essential oils as natural preservatives in the food and cosmetic sectors have been recognized. The essential oil is deemed safe and non-hazardous, displaying no mutagenic or cytotoxic effects. Despite the extensive historical use of this traditional medicinal plant in Ethiopia, the limited scientific investigations on its genetic improvement, cultivation practices, and integration into modern healthcare pose a notable challenge. This review aims to furnish a comprehensive discourse on the historical and contemporary applications of traditional damakase in Ethiopian traditional medicine.

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Herbal Medicine Use During Pregnancy: A Review of the Literature With a Special Focus on Sub-Saharan Africa

Hajj

Holst

2020

Front. Pharmacol.

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Herbal medicine use has grown considerably worldwide among pregnant women, and is particularly widespread in sub-Saharan Africa. However, herbal medicines used across sub-Saharan Africa are associated with important research gaps and a lack of regulatory framework. This is particularly problematic, as herbal medicine use during pregnancy raises several concerns attributed to the herbal ingredient itself, conventional drug-herbal medicine interactions, and contamination or adulteration of herbal remedies. Moreover, several local herbal remedies used by sub-Saharan African pregnant women have never been botanically identified. In this review, an overview of the practice of herbal medicine, including the regulations, challenges and overall safety, is provided. Then, we discuss the prevalence of herbal medicine use during pregnancy across different sub-Saharan African countries, as well as the indications, adverse outcomes, and effectiveness of the most commonly used herbal medicines during pregnancy in that region.

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A review of natural remedies commonly used by Ethiopian immigrants in the USA

Cited by 3 publications

References 8 publications

Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract of Moringa stenopetala Baker f. in Mice

Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract of Moringa stenopetala Baker f. in Mice

Damakase (<i>Ocimum lamiifolum</i> Hochest ex Benth): A Medicinal Plant Used in Ethiopian Traditional Medicine: A Critical Review

Herbal Medicine Use During Pregnancy: A Review of the Literature With a Special Focus on Sub-Saharan Africa

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A review of natural remedies commonly used by Ethiopian immigrants in the USA

Cited by 3 publications

References 8 publications

Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract of Moringa stenopetala Baker f. in Mice

Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract of Moringa stenopetala Baker f. in Mice

Damakase (&lt;i&gt;Ocimum lamiifolum&lt;/i&gt; Hochest ex Benth): A Medicinal Plant Used in Ethiopian Traditional Medicine: A Critical Review

Herbal Medicine Use During Pregnancy: A Review of the Literature With a Special Focus on Sub-Saharan Africa

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Damakase (<i>Ocimum lamiifolum</i> Hochest ex Benth): A Medicinal Plant Used in Ethiopian Traditional Medicine: A Critical Review