A review of optical methods for ultrasensitive detection and characterization of nanoparticles in liquid media with a focus on the wide field surface plasmon microscopy

Nizamov, Shavkat; Sazdovska, Simona Dimchevska; Mirsky, Vladimir M.

doi:10.1016/j.aca.2022.339633

Cited by 33 publications

(26 citation statements)

References 208 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It enables the observation of any type of nanoobject deposited on or near a thin plasmonic Au electrode in the surface plasmon resonance microscopy (SPRM) configuration. 325,337,338 At nonplasmonic (transparent) electrodes, TIR illumination allows tracking the growth of nanodendrites with nm spatial resolution. 339,340 It has particularly been used to image the formation of EDL at individual NPs.…”

Section: Methodologies For Quantitative Image Analysismentioning

confidence: 99%

The new era of high throughput nanoelectrochemistry

Valavanis

Ciocci

et al. 2022

Preprint

View full text Add to dashboard Cite

Scanning electrochemical probe microscopies (SEPMs) have played a key role in advancing small-scale electrochemistry. SEPMs use an electrochemical probe (micro/nanoelectrode or pipet) to quantify and map local interfacial fluxes of electroactive species and have found increasingly wide applications. Our contribution to the Fundamental and Applied Reviews in Analytical Chemistry 2019 discussed how advances in SEPMs converged towards nanoscale electrochemical mapping. This inflection in experimental capability has opened up myriad opportunities for SEPMs in many types of systems, from material and energy sciences to the life sciences. The enhancement in the spatial resolution of imaging techniques, and instrumental developments, have resulted in significant increases in the size of electrochemical datasets from a typical experiment and served to speed up measurement throughput. Next generation nanoelectrochemistry will thus see an emphasis on “big data”, its analysis, storage and curation, high throughput analysis and parallelization, “intelligent” instruments and experiments, active control of nanoscale systems, and the integration of nanoelectrochemistry and nanoscale micro(spectro)scopy. For this review article, we focus on recent advances in frontier nanoscale electrochemistry, analysis and imaging techniques that are already addressing some of these key targets, and are well-placed to embrace other aspects in the near future. Our goal is to provide an overview of the present state-of-the-art in high throughput nanoelectrochemistry and imaging, and signpost promising new avenues for nanoscale electrochemical methods.

show abstract

Section: Methodologies For Quantitative Image Analysismentioning

confidence: 99%

The new era of high throughput nanoelectrochemistry

Valavanis

Ciocci

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…TIR illumination is also used with label-free microscopies. It enables the observation of any type of nanoobject deposited on or near a thin plasmonic Au electrode in the surface plasmon resonance microscopy (SPRM) configuration. ,, At nonplasmonic (transparent) electrodes, TIR illumination allows tracking the growth of nanodendrites with nanometer spatial resolution. , It has particularly been used to image the formation of EDL at individual NPs …”

Section: Optical Microscopies In Electrochemistrymentioning

confidence: 99%

The New Era of High-Throughput Nanoelectrochemistry

Valavanis

Ciocci

et al. 2023

Anal. Chem.

View full text Add to dashboard Cite

“…Optical spectroscopic techniques that exploit material light absorption, scattering, and photoluminescence properties have been used extensively in chemical, biological, and environmental measurements for applications such as fundamental material characterization, − phototcatalysis, , industrial process control, , and quality assurance. − Fundamental theories have been developed for correlating the optical spectroscopic signals with the materials’ photophysical properties and analyte concentrations. The most well-known example is Beer’s law that correlates the UV–vis spectral intensity with the analyte concentrations and molar extinction coefficient.…”

Section: Introductionmentioning

confidence: 99%

Effects of Cascading Optical Processes: Part I: Impacts on Quantification of Sample Scattering Extinction, Intensity, and Depolarization

et al. 2023

View full text Add to dashboard Cite

Light scattering is a universal matter property that is especially prominent in nanoscale or larger materials. However, the effects of scattering-based cascading optical processes on experimental quantification of sample absorption, scattering, and emission intensities, as well as scattering and emission depolarization, have not been adequately addressed. Using a series of polystyrene nanoparticles (PSNPs) of different sizes as model analytes, we present a computational and experimental study on the effects of cascading light scattering on experimental quantification of NP scattering activities (scattering cross-section or molar coefficient), intensity, and depolarization. Part II and Part III of this series of companion articles explore the effects of cascading optical processes on sample absorption and fluorescence measurements, respectively. A general theoretical model is developed on how forward scattered light complicates the general applicability of Beer's law to the experimental UV−vis spectrum of scattering samples. The correlation between the scattering intensity and PSNP concentration is highly complicated with no robust linearity even when the scatterers' concentration is very low. Such complexity arises from the combination of concentration-dependence of light scattering depolarization and the scattering inner filter effects (IFEs). Scattering depolarization increases with the PSNP scattering extinction (thereby, its concentration) but can never reach unity (isotropic) due to the polarization dependence of the scattering IFE. The insights from this study are important for understanding the strengths and limitations of various scattering-based techniques for material characterization including nanoparticle quantification. They are also foundational for quantitative mechanistic understanding on the effects of light scattering on sample absorption and fluorescence measurements.

show abstract

A review of optical methods for ultrasensitive detection and characterization of nanoparticles in liquid media with a focus on the wide field surface plasmon microscopy

Cited by 33 publications

References 208 publications

The new era of high throughput nanoelectrochemistry

The new era of high throughput nanoelectrochemistry

The New Era of High-Throughput Nanoelectrochemistry

Effects of Cascading Optical Processes: Part I: Impacts on Quantification of Sample Scattering Extinction, Intensity, and Depolarization

Contact Info

Product

Resources

About