A review of sources, levels, and toxicity of polybrominated diphenyl ethers (PBDEs) and their transformation and transport in various environmental compartments

Akortia, Eric; Okonkwo, Jonathan O.; Lupankwa, Mlindelwa; Osae, S.; Daso, Adegbenro P.; Olukunle, Olubiyi I.; Chaudhary, Abdul J.

doi:10.1139/er-2015-0081

Cited by 84 publications

(31 citation statements)

References 221 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other groups of chemicals, such as persistent organic pollutants (POPs), are of concern due to their persistence, bioconcentration and biomagnification effects [9]. Finally, a growing concern about the relation between pollution, and toxic algal communities has arisen.…”

Section: Introductionmentioning

confidence: 99%

“…One of the challenges to accomplish the required aim was to be able to simultaneously detect and quantify different families of chemical contaminants with minimum or without any sample preparation, at very low concentration levels, on a device able to work autonomously in situ (ocean, aquaculture facilities, etc). In the last years a variety of multiresidue chromatographic methods, usually coupled to tandem mass spectrometry showing high specificity and sensitivity have been reported (LC-MS/MS or GC-MS/MS) [9,[12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fluorescent microarray for multiplexed quantification of environmental contaminants in seawater samples

Sanchís

Salvador

Campbell

et al. 2018

Talanta

View full text Add to dashboard Cite

The development of a fluorescent multiplexed microarray platform able to detect and quantify a wide variety of pollutants in seawater is reported. The microarray platform has been manufactured by spotting 6 different bioconjugate competitors and it uses a cocktail of 6 monoclonal or polyclonal antibodies raised against important families of chemical pollutants such as triazine biocide (i.e. Irgarol 1051®), sulfonamide and chloramphenicol antibiotics, polybrominated diphenyl ether flame-retardant (PBDE, i.e. BDE-47), hormone (17β-estradiol), and algae toxin (domoic acid). These contaminants were selected as model analytes, however, the platform developed has the potential to detect a broader group of compounds based on the cross-reactivity of the immunoreagents used. The microarray chip is able to simultaneously determine these families of contaminants directly in seawater samples reaching limits of detection close to the levels found in contaminated areas (Irgarol 1051®, 0.19 ± 0,06 µg L; sulfapyridine, 0.17 ± 0.07 µg L; chloramphenicol, 0.11 ± 0.03 µg L; BDE-47, 2.71 ± 1.13 µg L; 17β-estradiol, 0.94 ± 0.30 µg L and domoic acid, 1.71 ± 0.30 µg L). Performance of the multiplexed microarray chip was assessed by measuring 38 blind spiked seawater samples containing either one of these contaminants or mixtures of them. The accuracy found was very good and the coefficient of variation was < 20% in all the cases. No sample pre-treatment was necessary, and the results could be obtained in just 1 h 30 min. The microarray shows high sample throughput capabilities, being able to measure simultaneously more than 68 samples and screen them for a significant number of chemical contaminants of interest in environmental screening programs.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fluorescent microarray for multiplexed quantification of environmental contaminants in seawater samples

Sanchís

Salvador

Campbell

et al. 2018

Talanta

View full text Add to dashboard Cite

show abstract

“…Though some highly-toxic PBDEs have been banned in many countries, other PBDEs with relatively lower toxicity, such as BDE-209, are still largely produced and used in the world (Chen et al, 2012;Akortia et al, 2016). Although the concentration of PBDEs in the human blood is generally low in most places, it has been reported that the concentrations of PBDEs in the human blood of workers can reach significantly high levels in many heavily polluted areas (Jin et al, 2009;Makey et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

In vitro cytotoxicity of decabrominated diphenyl ether (PBDE-209) to human red blood cells (hRBCs)

et al. 2017

View full text Add to dashboard Cite

“…(5) E U R A C H E M / C I TA C , 2 0 0 3 , " T r a c e a b i l i t y i n c h e m i c a l measurement: A guide to achieving comparable results in chemical measurement"; (1,4). Senyawa ini digunakan sebagai flame retardant yaitu zat aditif yang ditambahkan dalam material atau bahan agar memenuhi standar legitimasi sifat flammable (mudah terbakar) (7), dengan tujuan untuk membuat suatu material menjadi lebih tahan terhadap api.…”

Section: Daftar Pustakaunclassified

“…Validasi metode pengukuran gas dengan peralatan gas analyzer dilakukan secara perbandingan langsung dengan certified span gas (CSG) yang tertelusur ke sistem satuan internasional melalui rantai perbandingan yang tidak terputus [2][3][4][5]. Adapun lingkup validasi metode pengukuran meliputi gas O 2 , CO, NO, NO 2 , SO 2 , CH 4 dan H 2 S yang ditentukan nilai accuracy, repeatability atau stability, linearity dan calibration and measurement capability (CMC).…”

unclassified

Validasi Metode Kalibrasi Gas Analyzer Untuk Pengukuran O2, Co, No, No2, So2, Ch4, Dan H2s Secara Perbandingan Langsung Dengan Ceritified Span Gas

Hadi¹,

Subarja²,

Firdaus³

2017

Ecolab

View full text Add to dashboard Cite

ABSTRAKSalah satu persyaratan validasi data pengukuran gas adalah dilakukan oleh personel yang kompeten dengan menggunakan gas analyzer yang terkalibrasi dan pengunaan metode tervalidasi. Validasi metode pengukuran gas dengan peralatan gas analyzer dilakukan secara perbandingan langsung dengan certified span gas (CSG) yang tertelusur ke sistem satuan internasional melalui rantai perbandingan yang tidak terputus. Tujuan validasi metode kalibrasi adalah untuk mendapatkan informasi penting dalam menilai kemampuan serta keterbatasan metode kalibrasi. Validasi metode kalibrasi gas analyzer O 2 , CO, NO, NO 2 , SO 2 , CH 4 , dan H 2 S menghasilkan akurasi, presisi dan linieritas memenuhi kriteria batas keberterimaan yang telah ditentukan yaitu % R ≤ 2% relatif, % RSD ≤ 0,5 nilai horwitz dan koefisien determinasi ≥ 0,990. Kemampuan kalibrasi dan pengukuran digunakan sebagai informasi atas kemampuan pengukuran dan kalibrasi serta ketidakpastian yang dicapai yang tersedia bagi pelanggan dalam kondisi normal. Dengan demikian, metode kalibrasi gas analyzer yang telah divalidasi dapat digunakan untuk mengukur sampel gas untuk kebutuhan pelanggan.Kata kunci: validasi metode, certified span gas, zero gas, gas analyzer, calibration and measurement capability ABSTRACT One of the requirements for data validation of gas measurement with gas analyzer is performed by competent personnel using calibrated gas analyzer and validation of method. The validation of calibration method for the gas analyzer is carried out in direct comparison to the certified span gas (CSG) which is traceable to the international unit system through an unbroken chain of comparison. The purpose of calibration method validation is to obtain important information in assessing the capabilities as well as the limitations of the calibration methods. Validation of calibration method for O 2 , CO, NO, NO 2 , SO 2 , CH 4 , and H 2 S analyzer resulted in accuracy, precision and linearity that meets the predetermined acceptance limit criteria are in which % R ≤ 2% relative,% RSD ≤ 0,5 Horwitz value and coefficient of determination ≥ 0.990. The Calibration and Measurement Capability (CMC) obtained is the most precise uncertainty value that the laboratory could achieve in gas analyzer calibration routine services. Calibration and measurement capability (CMC) is used as information on measurement and calibration capability including uncertainty available to customers under normal conditions. Thus, the validated calibration method for gas analyzer can be used for measuring the gas sample for customer needs. menggunakan peralatan ukur yang telah dikalibrasi serta sumber daya laboratorium yang mendukung, penggunaan metode 1) P3KLL-KLHK, ABSTRAKPolybrominated diphenyl ether (PBDEs) merupakan unsur pembentuk material tahan api. PBDEs berpotensi menimbulkan efek negatif terhadap mahluk hidup akibat memiliki sifat persisten, toksisitas, dan bioakumulatif. Pengukuran PBDEs dilakukan dengan pengambilan sampel menggunakan Polyurethane foam-disk (PUF-disk) yang dipasang pada passive...

show abstract

A review of sources, levels, and toxicity of polybrominated diphenyl ethers (PBDEs) and their transformation and transport in various environmental compartments

Cited by 84 publications

References 221 publications

Fluorescent microarray for multiplexed quantification of environmental contaminants in seawater samples

Fluorescent microarray for multiplexed quantification of environmental contaminants in seawater samples

In vitro cytotoxicity of decabrominated diphenyl ether (PBDE-209) to human red blood cells (hRBCs)

Validasi Metode Kalibrasi Gas Analyzer Untuk Pengukuran O2, Co, No, No2, So2, Ch4, Dan H2s Secara Perbandingan Langsung Dengan Ceritified Span Gas

Contact Info

Product

Resources

About