A review of stress‐related mucosal disease

Monnig, Andrea A.; Prittie, Jennifer

doi:10.1111/j.1476-4431.2011.00680.x

Cited by 30 publications

(26 citation statements)

References 105 publications

(230 reference statements)

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“…Table 1 Changes of antral and duodenal myoelectric activities after ethylic acid induction (n = 9-16, mean ± SD). blood flow, surface epithelial cells, prostaglandin, gastric motility, and others [29,30] . Acetic acid-induced DU model is similar to human's chronic DU by eroding intestinal wall (defensive factor), and it is beneficial to observe the repairing effect of S. lappa on ulcer.…”

Section: Serum Level Of Motilin Among the Groupsmentioning

confidence: 99%

Saussurea Lappa Modulates Gastrointestinal Motility, Motilin and Cholecystokinin Expression in Ulcer Rats

Zhang

Wang

et al. 2016

Journal of Gastroenterology and Hepatology Research

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cholecystokinin and motilin secretion decrease. Similarity to Omeprazole, S. lappa accelerated the coalescence of ethylic acidinduced duodenal ulcer significantly (p < 0.01, vs model group), but no obvious dose-dependent effect was found. S. lappa also improved gastrointestinal myoelectric activity and accelerated intestinal propulsion. Furthermore, S. lappa could increase the expression levels of cholecystokinin and motilin in duodenum and increase motilin level in serum. CONCLUSION: S. lappa can accelerate the coalescence of chronic duodenal ulcer, and increase gastrointestinal myoelectric activity and the expression of cholecystokinin and motilin in duodenum.

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Section: Serum Level Of Motilin Among the Groupsmentioning

confidence: 99%

Saussurea Lappa Modulates Gastrointestinal Motility, Motilin and Cholecystokinin Expression in Ulcer Rats

Zhang

Wang

et al. 2016

Journal of Gastroenterology and Hepatology Research

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“…Upper gastrointestinal bleeding is usually presented clinically in SU and once bleeding starts to happen, the mortality rate significantly increases. 1 Therefore an SU is a cause of acute non-variceal upper gastrointestinal bleeding (ANVUGIB). Omeprazole is a representative drug of proton pump inhibitors (PPIs), and its therapeutic effect for ANVUGIB has been affirmed.…”

Section: Introductionmentioning

confidence: 99%

The therapeutic effect of high-dose esomeprazole on stress ulcer bleeding in trauma patients

Cui

Wang

et al. 2015

Chinese Journal of Traumatology

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a b s t r a c tPurpose: To compare the therapeutic effects of different doses of intravenous esomeprazole on treating trauma patients with stress ulcer bleeding. Methods: A total of 102 trauma patients with stress ulcer bleeding were randomly divided into 2 groups: 52 patients were assigned to the high-dose group who received 80 mg intravenous esomeprazole, and then 8 mg/h continuous infusion for 3 days; 50 patients were assigned to the conventional dose group who received 40 mg intravenous esomeprazole sodium once every 12 h for 72 h. Results: Compared with the conventional dose group, the total efficiency of the high-dose group and conventional dose group was 98.08% and 86.00%, respectively (p < 0.05), the hemostatic time was 22.10 h ± 5.18 h and 28.27 h ± 5.96 h, respectively (p < 0.05). Conclusion: Both doses of intravenous esomeprazole have good hemostatic effects on stress ulcer bleeding in trauma patients. The high-dose esomeprazole is better for hemostasis.

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“…It is defined as a lesion of the gastric mucosa when elderly patients are exposed to severe emotional or physical stress [1]. Stress describes the sum of reactions to an adverse stimulus [2].…”

Section: Introductionmentioning

confidence: 99%

Stress ulcer prophylaxis, thromboprophylaxis and coagulation management in patients with hip fractures

Thaler

Dovjak²,

Iglseder

et al. 2013

Wien Med Wochenschr

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Hip fracture in older patients is a major health concern. 20-25 % of hip fracture patients will die in the first year after the trauma (Lane, Clin Orthop Relat Res 471(8):2711, 2013). Postoperative venous thrombosis and gastrointestinal stress-ulcer bleeding are frequent complications with a high case-fatality rate particularly in older patients. Thromboprophylaxis and stress ulcer prophylaxis are important and well established measures to decrease postoperative complications and the mortality rate in this high-risk population.The working group on orthogeriatrics of the Austrian Society on Geriatrics and Gerontology (ÖGGG) is composed of geriatricians who work as trauma surgeons, internists, anaestesists and nurses. A thorough literature search was done, using the terms "orthogeriatrics" and "hip fracture" in combination with "stress ulcer", "gastrointestinal bleeding" and "thrombosis", "thromboprophylaxis". The data was collected, discussed and evaluated in several adjustment meetings of the group and summarized in this article.

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A review of stress‐related mucosal disease

Cited by 30 publications

References 105 publications

Saussurea Lappa Modulates Gastrointestinal Motility, Motilin and Cholecystokinin Expression in Ulcer Rats

Saussurea Lappa Modulates Gastrointestinal Motility, Motilin and Cholecystokinin Expression in Ulcer Rats

The therapeutic effect of high-dose esomeprazole on stress ulcer bleeding in trauma patients

Stress ulcer prophylaxis, thromboprophylaxis and coagulation management in patients with hip fractures

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