A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics

Hoppe, Alexander; Güldal, Nusret S.; Boccaccını, Aldo R.

doi:10.1016/j.biomaterials.2011.01.004

Cited by 2,263 publications

(1,780 citation statements)

References 224 publications

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“…This formulation has been used in a variety of commercial bone graft materials as it stimulates healing and induces regeneration of bone tissue [28]. Recent research has also demonstrated the potential of bioactive glass as a bone tissue scaffold material [27,29].…”

Section: The Role Of Powder Bedmentioning

confidence: 99%

Powder bed generation in integrated modelling of additive layer manufacturing of orthopaedic implants

Krzyżanowski

Svyetlichnyy

Stevenson

et al. 2016

Int J Adv Manuf Technol

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This paper presents an original model of powder bed generation developed within the frame of an integrated modelling approach for studying the interaction of physical mechanisms in additive layer manufacturing (ALM) of orthopaedic implants. The model is based on cellular automata (CA) approach and describes the relationship between moving particles of different sizes during deposition on a surface in three dimensions. The surface is defined by the horizontal two-dimensional CA on which particles fall and irreversibly stick to a growing deposit. The model allows for consideration of different restructuring cases when particles are allowed to rotate as often as necessary until achievement of a local minimum position. Changes in the packing density of the powder bed have been investigated numerically depending on technological parameters, such as particle size distribution, deposition rate and sequence of powder deposition. The model has been developed with the aim of merging to the finite element (FE)-based integrated model and is applicable to a different ranges of materials including metals and also non-metals.

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Section: The Role Of Powder Bedmentioning

confidence: 99%

Powder bed generation in integrated modelling of additive layer manufacturing of orthopaedic implants

Krzyżanowski

Svyetlichnyy

Stevenson

et al. 2016

Int J Adv Manuf Technol

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“…At these conditions, ion liberation used to be rapid and not maintained over time. A controllable release and optimal degradation kinetics are crucial but difficult to achieve (Hoppe et al, 2011). Dentin infiltration with polymeric nanoparticles as calcium and phosphate sequestering materials (i.e., carboxylate functionalized polymer particles that bind calcium) previous to the bonding procedure has been proposed (Osorio et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

“…Zinc influences signaling pathways and stimulates a metabolic effect in hard tissue mineralization (Hoppe et al, 2011) and remineralization processes (Barcellos et al, 2016;Lynch et al, 2011). Zinc elicits a specific biological response at the interface of the material which results in the formation of a bond between tissue and material (Kokubo et al, 1990).…”

Section: Introductionmentioning

confidence: 99%

Ions-modified nanoparticles affect functional remineralization and energy dissipation through the resin-dentin interface

Toledano

Osorio

et al. 2017

Journal of the Mechanical Behavior of Biomedical Materials

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The aim of this study was to evaluate changes in the mechanical and chemical behavior, and bonding ability at dentin interfaces infiltrated with polymeric nanoparticles (NPs) prior to resin application. Dentin surfaces were treated with 37% phosphoric acid followed by application of an ethanol suspension of NPs, Zn-NPs or Ca-NPs followed by the application of an adhesive, Single Bond (SB). Bonded interfaces were stored for 24 h, submitted to microtensile bond strength test, and evaluated by scanning electron microscopy. After 24 h and 21 d of storage, the whole resin-dentin interface adhesive was evaluated using a Nano-DMA. Complex modulus, storage modulus and tan delta (δ) were assessed. AFM imaging and Raman analysis were performed. Bond strength was not affected by NPs infiltration. After 21 d of storage, tan δ generally decreased at Zn-NPs/resin-dentin interface, and augmented when Ca-NPs or non-doped NPs were used. When both Zn-NPs and Ca-NPs were employed, the storage modulus and complex modulus decreased, though both moduli increased at the adhesive and at peritubular dentin after Zn-NPs infiltration. The phosphate and the carbonate peaks, and carbonate substitution, augmented more at interfaces promoted with Ca-NPs than with Zn-NPs after 21 d of storage, but crystallinity did not differ at created interfaces with both ions-doped NPs. Crosslinking of collagen and the secondary structure of collagen improved with Zn-NPs resin-dentin infiltration. Ca-NPs-resin dentin infiltration produced a favorable dissipation of energy with minimal stress concentration trough the crystalline remineralized resin-dentin interface, causing minor damage at this structure.

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“…Its bioactivity is associated with the formation of a carbonated hydroxyapatite layer (HCA) on its surface, similar to the bone mineral. [29,30] Glass-ceramics with crystalline or semicrystalline structures are produced by the transformation of the glass into a ceramic. [10] The sol-gel glasses offer several advantages compared with the melt-delivered glasses.…”

Section: Introductionmentioning

confidence: 99%

Electrophoretic Deposition, Microstructure, and Corrosion Resistance of Porous Sol–Gel Glass/Polyetheretherketone Coatings on the Ti-13Nb-13Zr Alloy

Moskalewicz

Zych

Łukaszczyk

et al. 2017

Metall Mater Trans A

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In this study, microporous composite sol-gel glass/polyetheretherketone (SGG/PEEK) coatings were produced on the Ti-13Nb-13Zr titanium alloy by electrophoretic deposition. Coatings with different levels of high open porosity were developed by introducing SGG particles of varying diameters into the PEEK matrix. The microstructure of the coatings was characterized by electron microscopy and X-ray diffractometry. The coatings with 40-50 lm thickness were composed of semicrystalline SGG particles consisting of hydroxyapatite, CaSiO 3 , some Ca 2 SiO 4 , and an amorphous phase containing Ca, Si, P, and O, homogeneously embedded in a semicrystalline PEEK matrix. The size of SGG particles present in the coatings strongly influenced the formation of microcracks and their adhesion to the underlying substrate. Microscratch tests showed that the coating containing SGG particles with a diameter smaller than 45 lm and open porosity of 45 pct exhibited good adhesion to the titanium alloy substrate, much better than the coating containing particles with a diameter smaller than 85 lm and total open porosity equal to 48 pct. The corrosion resistance was investigated in Ringer's solution at a temperature of 310 K (37°C) for a pH equal to 7.4 and in deaerated solutions with the use of open-circuit potential, potentiodynamic polarization, and electrochemical impedance spectroscopy. The SGG/PEEK-coated alloy indicated better electrochemical corrosion resistance compared with the uncoated alloy.

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A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics

Cited by 2,263 publications

References 224 publications

Powder bed generation in integrated modelling of additive layer manufacturing of orthopaedic implants

Powder bed generation in integrated modelling of additive layer manufacturing of orthopaedic implants

Ions-modified nanoparticles affect functional remineralization and energy dissipation through the resin-dentin interface

Electrophoretic Deposition, Microstructure, and Corrosion Resistance of Porous Sol–Gel Glass/Polyetheretherketone Coatings on the Ti-13Nb-13Zr Alloy

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