A review of β-glucans as a growth promoter and antibiotic alternative against enteric pathogens in poultry

Anwar, Muhammad İrfan; Muhammad, Faqir; Awais, Mian Muhammad; Akhtar, Masood

doi:10.1017/s0043933917000241

Cited by 40 publications

(37 citation statements)

References 66 publications

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“…Meeting the increasing demand of animal protein and providing safe food for human beings that is free from antibiotics by using herbal feed resources is a great challenge for the animal scientists in the future. The issue considering antibiotic resistance has created an augmented force to reduce antibiotic uses in livestock and poultry production [1,2]. Dietary inclusion of herbs and their extracts has growth-promoting roles in poultry [3].…”

Section: Introductionmentioning

confidence: 99%

Application of Moringa (Moringa oleifera) as Natural Feed Supplement in Poultry Diets

Mahfuz

Piao

2019

Animals

110

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Application of natural herbs with a view to enhancing production performance and health status has created an important demand in poultry production. With the increasing concerns on this issue, greater attention paid to alternatives to antibiotics for organic meat and egg production has led to a great demand. This study was conducted with view to assessing the possible role of M. oleifera as a natural feed supplement in poultry ration. Various scientific findings and published research articles were considered concerning issues including the study background, objectives, major findings, and conclusions of the review. M oleifera is known as a miracle tree because of its wealthy resource of various nutrients with high biological values. M. oleifera has been used as a growth promoter, immune enhancer, antioxidant, and has a hypo-cholesterol effect on chickens. It has both nutritional and therapeutic values. However, there is still much confusion in past published articles involving the major roles of M. oleifera in production performance and health status of chickens. Taking this into account, the present study highlights an outline of the experimental uses of M. oleifera on growth performance, egg production performance, egg quality, and health status in broilers and laying hens justified with the past findings to the present. The knowledge gaps from the past studies are considered, and the feasibility of M. oleifera in poultry ration is suggested. The findings have motivated further study on M. oleifera to find out the most active ingredients and their optimal doses in both broiler and laying hen rations. Finally, the present study highlights that supplementation of M. oleifera may play a role in the immunity, sound health, and production performance in poultry.

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Section: Introductionmentioning

confidence: 99%

Application of Moringa (Moringa oleifera) as Natural Feed Supplement in Poultry Diets

Mahfuz

Piao

2019

Animals

110

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“…In addition, the preparation includes an extract from the yeast strain Saccharomyces cerevisiae , which contains a large amount of peptides, a mannan oligosaccharide and a β-glucan, which binds pathogenic microorganisms, inhibits their attachment to cells,and increases the length of intestinal villi. Moreover, β-glucans increase the gene expression of tight junction proteins, thereby ensuring integrity of the intestinal wall in chickens ( Anwar et al., 2017 ). In mice, dendritic cell uptake of B. amyloliquefaciens SQR9 alone induced the expression of cytokines and secretion of sIgA ( Huang et al., 2016 ).…”

Section: Discussionmentioning

confidence: 99%

“…Likewise, β-glucans modulate the intestinal morphology by increasing the number of mucin-producing goblet cells, as well as cells expressing secretory IgA ( sIgA ) with increased sIgA in the intestinal lumen. At the same time, they reduce bacterial translocation to various other organs ( Anwar et al., 2017 ).…”

Section: Introductionmentioning

confidence: 99%

Influence of Lacto-Immuno-Vital on growth performance and gene expression of IgA, MUC-2, and growth factor IGF-2 in the jejunum of broiler chickens

et al. 2020

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The effects of Lacto-Immuno-Vital synbiotic preparation on gene expression of IgA, MUC-2, and growth factor IGF-2 in the jejunum and on BW gain in broiler chickens were studied. A flock of 64,400 1-day-old Hybrid ROSS 308 chickens was inducted in the 42-day experiment. The chickens were divided into 2 equally size groups in separate halls. The chickens in the experimental ( E ) group received 500 g of Lacto-Immuno-Vital in 1,000 L of drinking water. The preparation was administered daily from the first day (day 1) to day 7 of the experiment. From day 7 to day 22, it was given in pulsed manner (every third day) at a dose of 300 g in 1,000 L of drinking water. The broiler chickens in the E group gained more weight ( P < 0.001) compared with control from day 10 to day 42. Death of animals during feeding period was 1,078 chickens in the E group compared with 1,115 dead chickens in the control group. Feed conversion ratio was 1.61 kg of supplemented diet/kg of BW in the E group compare with 1.67 kg of nonsupplemented diet/kg of BW in control. The relative expression of IgA gene in the jejunum was upregulated on day 22 in the E group compared with control ( P < 0.05), whereas relative expression of MUC-2 gene was upregulated in the E group compared with control on day 8 and day 22 ( P < 0.05; P < 0.001). Similarly, relative expression of IGF-2 gene was upregulated in the E group compared with control on both samplings ( P < 0.01). The composition of Lacto-Immuno-Vital synbiotic preparation showed beneficial effects on growth performance, feed conversion ratio, morbidity, mortality, and selected parameters of mucosal immunity in the chicken jejunum.

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“…β-glucans are composed by polymerization of glucose through 1,3/1,6 β-glycoside linkages [109]. In addition to their occurring in the yeast cell wall, we can find β-glucans in other sources having different structures.…”

Section: β-Glucansmentioning

confidence: 99%

Immunomodulation of Avian Dendritic Cells under the Induction of Prebiotics

Zmrhal

Sláma

2020

Animals

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Although the immunomodulatory properties of prebiotics were demonstrated many years ago in poultry, not all mechanisms of action are yet clear. Dendritic cells (DCs) are the main antigen-presenting cells orchestrating the immune response in the chicken gastrointestinal tract, and they are the first line of defense in the immune response. Despite the crucial role of DCs in prebiotic immunomodulatory properties, information is lacking about interaction between prebiotics and DCs in an avian model. Mannan-oligosaccharides, β-glucans, fructooligosaccharides, and chitosan-oligosaccharides are the main groups of prebiotics having immunomodulatory properties. Because pathogen-associated molecular patterns on these prebiotics are recognized by many receptors of DCs, prebiotics can mimic activation of DCs by pathogens. Short-chain fatty acids are products of prebiotic fermentation by microbiota, and their anti-inflammatory properties have also been demonstrated in DCs. This review summarizes current knowledge about avian DCs in the gastrointestinal tract, and for the first-time, their role in the immunomodulatory properties of prebiotics within an avian model.

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A review of β-glucans as a growth promoter and antibiotic alternative against enteric pathogens in poultry

Cited by 40 publications

References 66 publications

Application of Moringa (Moringa oleifera) as Natural Feed Supplement in Poultry Diets

Application of Moringa (Moringa oleifera) as Natural Feed Supplement in Poultry Diets

Influence of Lacto-Immuno-Vital on growth performance and gene expression of IgA, MUC-2, and growth factor IGF-2 in the jejunum of broiler chickens

Immunomodulation of Avian Dendritic Cells under the Induction of Prebiotics

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