A Review on Heavy Metal Contamination in Herbals

Shelar, Maruti; Gawade, Vaibhav; Bhujbal, Santosh S.

doi:10.9734/jpri/2021/v33i29a31561

Cited by 9 publications

(4 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, 75% of the traditional herbal remedies (T2, T3 and T4) exceeded twice those limits. Although Cu is necessary for the body, its excess in the diet is related to irritation of the upper respiratory tract, abdominal pain, dermatitis, vomiting, diarrhea, nausea and liver damage [ 78 ], so it is important that intake is within permissible limits for humans.…”

Section: Discussionmentioning

confidence: 99%

“…This is because it can cause damage to reproductive tissues and contribute to infertility [ 80 ]. It also damages the kidney and lungs, which can result in pulmonary edema and death, and damages bones, leading to osteoporosis and spontaneous fractures, as well as increased blood pressure [ 78 ]. Severe exposure also causes alterations in behavior and learning ability [ 80 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Human Health Risk Assessment of Arsenic and Other Metals in Herbal Products Containing St. John’s Wort in the Metropolitan Area of Mexico City

Rojas,

Ruiz-Sánchez,

Rojas

et al. 2023

Toxics

View full text Add to dashboard Cite

Consumption of St. John’s wort plant is high worldwide due to its various medicinal properties. However, herbal products containing St. John’s wort may be contaminated with toxic metals. This is often related to contamination of both water and the atmosphere, lack of proper cultivation methods, and inadequate plant storage conditions, as well as a lack of stricter sanitary supervision. A safety assessment of copper (Cu), lead (Pb), cadmium (Cd) and arsenic (As) content in 23 products containing St. John’s wort (pharmaceutical herbal products, food supplements and traditional herbal remedies) sold in the metropolitan area of Mexico City was conducted. The analysis of metals was determined using a graphite-furnace atomic absorption spectrometer. All herbal products were contaminated with Cu, Pb, Cd and As. The pharmaceutical herbal items showed less contamination by metals. The daily human intake (DHI) values for Pb exceeded the permissible limits in the group of traditional herbal remedies. The DHI calculation for As exceeded the permitted intake values for all items in the group of traditional herbal remedies, five food supplements and one pharmaceutical herbal product. The hazard indicator calculation of the non-carcinogenic cumulative risk values for traditional herbal remedies was greater than 1, suggesting a risk to human health.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Human Health Risk Assessment of Arsenic and Other Metals in Herbal Products Containing St. John’s Wort in the Metropolitan Area of Mexico City

Rojas,

Ruiz-Sánchez,

Rojas

et al. 2023

Toxics

View full text Add to dashboard Cite

show abstract

“…A foremost way of exposure to heavy metals is the consumption of contaminated food worldwide, and one out of ten individuals becomes affected [ 24 ]. It has been found that heavy metal exposure is increasing the risk of cardiovascular, neurological, renal diseases, digestive infections, cancer, and more than 200 risks of acute and chronic diseases [ 24 , 29 , 30 ]. For instance, in Bangladesh, the cancer-related demise rate was 7.5% in 2005 and will reach up to 13% by 2030, which is almost twice the rate of 2005.…”

Section: Introductionmentioning

confidence: 99%

Lead Exposure of Four Biologically Important Common Branded and Non-branded Spices: Relative Analysis and Health Implication

Alam

Hosen

Ullah

et al. 2023

Biol Trace Elem Res

View full text Add to dashboard Cite

Technological advances and socioeconomic development of Bangladesh are leading to the best choice between branded and non-branded powdered spices. But toxic metal issues can be another factor to elect them. So lead (Pb) exposure and its consequence on the human body for these two categories of four common spices have been ascertained here. A validated laboratory method using hot plate digestion and flame atomic absorption spectrometry (FAAS) has been used for that. The obtained mean concentration of Pb in branded and non-branded spice powders followed the decreasing order of turmeric > coriander > red chili > cumin powder and turmeric > red chili > cumin > coriander powder, respectively, where, in any analysis mode, the non-branded items are potentially ahead of Pb exposure. The market-based mean concentration between these two categories was not a significant difference ( t -test). Approximately 90% of the spice samples have shown within the maximum allowable limit by Bangladesh Standard. The sum of estimated daily intake indicated that most of the city market (67%) for non-branded items and some branded (33%) samples have crossed the maximum tolerable daily intake (> 0.21 mg/kg). So, the human health risk assumption for the inhabitant of studied areas suggests there is no significant level of risk for them due to the consumption of spices regarding non-carcinogenic risk factor (THQ and total THQ) and carcinogenic risk factor (CR). But the development of a quality control process for loose spice powders as well as toxic metal screening from raw materials to finish products urgently needed and continuous monitoring with identifying the source of toxic metal is highly recommended.

show abstract

“…Heavy metals also damage the normal functioning of the nervous systems 19 , cause hearing and speech difficulties 20 , lack of coordination 17 , memory loss, unusual heart rhythm 21 , stunted growth, learning disabilities 22 , cancers 23 and even death 24 . Heavy metals levels above maximum permissible limits have been detected in herbal drugs globally 25 . These metals are harmful and could be detrimental to the health of consumers 26 .…”

mentioning

confidence: 99%

Untitled

2022

IJPSR

View full text Add to dashboard Cite

This study looked at heavy metal levels in selected registered herbal drugs of Asian and unregistered Ghanaian herbal drugs sold in Kumasi. It examined the health risks of the metals. It provided authorities with data to ensure that herbal drugs are strictly monitored and their metal levels evaluated to safeguard patrons' health. Dry ashing method was used on 10g of each of the herbal drug samples. Ashes were digested at 95 ºC with 70% HNO 3 and 70% HClO 4 (2:5v/v), and then metals were analyzed using Atomic Absorption Spectrophotometer (AAS). The Asian drugs recorded 27.42E-01 mg/kg (Fe), 28.17E-0 4 mg/kg (Pb), 27.43E-0 4 mg/kg, 12.06E-06E-0 2 mg/kg (As) and 79.72E-0 2 mg/kg (Cu) whilst the Ghanaian drugs recorded mean levels of 15.43E-01 mg/kg (Fe), 24.99E-02 mg/kg (Pb), 16.04E-03 mg/kg, 47.70E-0 4 mg/kg (AS) and 12.37E-0 4 mg/kg. Metal levels in drugs were below WHO and Pharmacopeia (China) permitted levels. HI and HQ were below 1, indicating that risk linked to the metals were acceptable. INTRODUCTION:Globally, approximately 80% of the population depend on herbal remedies to treat and manage diseases such as diabetes, stroke, and hypertension, among others 1 . Herbal drugs play a vital role in the healthcare delivery schemes of numerous countries and are either selfprescribed or recommended by herbal practitioners QUICK RESPONSE CODE

show abstract

A Review on Heavy Metal Contamination in Herbals

Cited by 9 publications

References 15 publications

Human Health Risk Assessment of Arsenic and Other Metals in Herbal Products Containing St. John’s Wort in the Metropolitan Area of Mexico City

Human Health Risk Assessment of Arsenic and Other Metals in Herbal Products Containing St. John’s Wort in the Metropolitan Area of Mexico City

Lead Exposure of Four Biologically Important Common Branded and Non-branded Spices: Relative Analysis and Health Implication

Untitled

Contact Info

Product

Resources

About