A Review on Medicinal Properties of Orientin

Abstract

Medicinal plants continue to play an important role in modern medications and healthcare as consumers generally believe that most of them cause fewer or milder adverse effects than the conventional modern medicines. In order to use the plants as a source of medicinal agents, the bioactive compounds are usually extracted from plants. Therefore, the extraction of bioactive compounds from medicinal plants is a crucial step in producing plant-derived drugs. One of the bioactive compounds isolable from medicinal plants, orientin, is often used in various bioactivity studies due to its extensive beneficial properties. The extraction of orientin in different medicinal plants and its medicinal properties, which include antioxidant, antiaging, antiviral, antibacterial, anti-inflammation, vasodilatation and cardioprotective, radiation protective, neuroprotective, antidepressant-like, antiadipogenesis, and antinociceptive effects, are discussed in detail in this review.

Resistance associated metabolite profiling of Aspergillus leaf spot in cotton through non-targeted metabolomics

“…Different flavonoids like phlorizin, orientin, quercetin, kaempferol and isoflavanoids were also induced abundantly after pathogen inoculation in resistant cultivar. These have been proposed to be involved in disease resistance against various pathogens [42,43,44,45,46,47].…”

Antifungal, Antitumoral and Antioxidant Potential of the Danube Delta Nymphaea alba Extracts

“…Epicatechin anticancer activity [60,88] 25 Apigenin anticancer effect by arresting cell development at the G0/G1 phase; the inhibition of phosphorylation of mitogen-activated protein kinase (MAPK) [60] 26 Orientin antioxidant, antiviral and antibacterial activities, anti-inflammatory neuroprotective or antidepressant-like effects [89] 3. Materials and Methods…”

Orientin Protects Podocytes from High Glucose Induced Apoptosis through Mitophagy

“…Trigonella foenum‐graecum (fenugreek) seed is a well‐known traditional medicinal herb and possesses antidiabetic, hepatoprotective, antihyperlipidemic, antiobesity, anticancer, anti‐inflammatory, antioxidant, and miscellaneous pharmacological effects. Orientin, one of the isolable bioactive compounds of Fenugreek, is often used in various bioactivity studies due to its extensive beneficial properties, such as antioxidant, anti‐inflammation, cardioprotective, neuroprotective, antidepressant‐like, anti‐adipogenesis, and antinociceptive effects . In a word, orientin is one of the important bioactive components of fenugreek, and the fenugreek has been proved to have a therapeutic effect on diabetes and DN, and orientin itself also has many functions such as anti‐inflammatory and antioxidation .…”

“…[29] In a word, orientin is one of the important bioactive components of fenugreek, and the fenugreek has been proved to have a therapeutic effect on diabetes and DN, [30,31] and orientin itself also has many functions such as anti-inflammatory and antioxidation. [29] Meanwhile, the oxidative stress pathway in the pathogenesis of diabetes and DN is very important. To our knowledge, there are few studies on orientin in DN and podocytes.…”